Improving CAR T-cell and monoclonal antibody treatment through epitope editing

by Justin Jackson , Medical XpressCredit: CC0 Public DomainIn a paper, "Epitope editing enables targeted immunotherapy of acute myeloid leukaemia," published inNature, researchers at t

Updated on: January 07,2024

Improving CAR T-cell and monoclonal antibody treatment through epitope editing

by Justin Jackson , Medical XpressCredit: CC0 Public DomainIn a paper, "Epitope editing enables targeted immunotherapy of acute myeloid leukaemia," published inNature, researchers at t

Updated on:January 07,2024

Researchers advance role of circulating tumor DNA to detect early melanoma growth

by Johns Hopkins University School of MedicineEvidence of disease activity detected in circulating tumor DNA (ctDNA) predicts radiographic melanoma progression. Credit: Johns Hopkins Kimmel Cance

Updated on: June 04,2024

Researchers advance role of circulating tumor DNA to detect early melanoma growth

by Johns Hopkins University School of MedicineEvidence of disease activity detected in circulating tumor DNA (ctDNA) predicts radiographic melanoma progression. Credit: Johns Hopkins Kimmel Cance

Updated on:June 04,2024

Researchers key to advance care planning with cancer clinical trial patients

by University of Pennsylvania School of NursingConnie M. Ulrich, PhD, RN, FAAN, the Lillian S. Brunner Chair in Medical and Surgical Nursing at the University of Pennsylvania School of Nursing (P

Updated on: June 15,2024

Researchers key to advance care planning with cancer clinical trial patients

by University of Pennsylvania School of NursingConnie M. Ulrich, PhD, RN, FAAN, the Lillian S. Brunner Chair in Medical and Surgical Nursing at the University of Pennsylvania School of Nursing (P

Updated on:June 15,2024

Unlocking the body's hidden weapon against cancer: The role of broken chromosomes

by Zhejiang UniversityCredit: Pixabay/CC0 Public DomainScientists have unraveled the mechanisms of the cyclic guanosine monophosphate-adenosine monophosphate synthase-stimulator of interferon genes (c

Updated on: April 28,2024

Unlocking the body's hidden weapon against cancer: The role of broken chromosomes

by Zhejiang UniversityCredit: Pixabay/CC0 Public DomainScientists have unraveled the mechanisms of the cyclic guanosine monophosphate-adenosine monophosphate synthase-stimulator of interferon genes (c

Updated on:April 28,2024

Treatment beneficial for nonagenarians with lung cancer

(HealthDay)—Receiving treatment is associated with better survival for nonagenarians with non-small cell lung cancer (NSCLC), with the greatest survival benefit for stage I patients, according to a st

Updated on: April 10,2024

Treatment beneficial for nonagenarians with lung cancer

(HealthDay)—Receiving treatment is associated with better survival for nonagenarians with non-small cell lung cancer (NSCLC), with the greatest survival benefit for stage I patients, according to a st

Updated on:April 10,2024

Long exposure to protein inhibitor may be key to more effective chemotherapy for cancer

by Southern Methodist UniversityLong exposure to P-gp inhibitor and chemotherapy decreased cancer cell survival, as assessed by colony formation. Credit: SMUResearchers at SMU's Center for Dr

Updated on: April 18,2024

Long exposure to protein inhibitor may be key to more effective chemotherapy for cancer

by Southern Methodist UniversityLong exposure to P-gp inhibitor and chemotherapy decreased cancer cell survival, as assessed by colony formation. Credit: SMUResearchers at SMU's Center for Dr

Updated on:April 18,2024

Bolstering fat cells offers potential new leukemia treatment

by McMaster UniversityFat cells (white circles) in healthy human bone marrow, left, compared to bone marrow in a patient with leukemia, right. Credit: McMaster UniversityKilling cancer cells indi

Updated on: April 14,2024

Bolstering fat cells offers potential new leukemia treatment

by McMaster UniversityFat cells (white circles) in healthy human bone marrow, left, compared to bone marrow in a patient with leukemia, right. Credit: McMaster UniversityKilling cancer cells indi

Updated on:April 14,2024

Researchers propose biomarkers to select breast cancer patients who could benefit from denosumab treatment

by The Spanish National Cancer Research CentreGraphical abstract. Credit:EMBO Molecular Medicine(2023). DOI: 10.15252/emmm.202216715The drug denosumab is currently used to treat osteo

Updated on: January 30,2024

Researchers propose biomarkers to select breast cancer patients who could benefit from denosumab treatment

by The Spanish National Cancer Research CentreGraphical abstract. Credit:EMBO Molecular Medicine(2023). DOI: 10.15252/emmm.202216715The drug denosumab is currently used to treat osteo

Updated on:January 30,2024

Study uncovers how B cells react to skin cancer

by King's College LondonSpatial transcriptomic coupled with high throughput intratumoral antibody repertoire analyses suggest an active but aberrant B cell response.aRepresentativ

Updated on: February 23,2024

Study uncovers how B cells react to skin cancer

by King's College LondonSpatial transcriptomic coupled with high throughput intratumoral antibody repertoire analyses suggest an active but aberrant B cell response.aRepresentativ

Updated on:February 23,2024

Researchers discover 40 genes involved in early development of myeloma

by Sarah Wells, The Institute of Cancer ResearchMicrograph of a plasmacytoma, the histologic correlate of multiple myeloma. H&E stain. Credit: Wikipedia/CC BY-SA 3.0Researchers have revealed 40 ge

Updated on: June 24,2024

Researchers discover 40 genes involved in early development of myeloma

by Sarah Wells, The Institute of Cancer ResearchMicrograph of a plasmacytoma, the histologic correlate of multiple myeloma. H&E stain. Credit: Wikipedia/CC BY-SA 3.0Researchers have revealed 40 ge

Updated on:June 24,2024

Link between sphingolipids and complement signaling may be key to stopping cancer metastasis

by Caroline Wallace,Medical University of South CarolinaGraphical Abstract. Credit:Cell Reports(2022). DOI: 10.1016/j.celrep.2022.111742MUSC Hollings Cancer Center researchers have i

Updated on: January 02,2024

Link between sphingolipids and complement signaling may be key to stopping cancer metastasis

by Caroline Wallace,Medical University of South CarolinaGraphical Abstract. Credit:Cell Reports(2022). DOI: 10.1016/j.celrep.2022.111742MUSC Hollings Cancer Center researchers have i

Updated on:January 02,2024

Origins of glioma brain cancer found to be in the epigenome

byDana-Farber Cancer InstituteCredit: Unsplash/CC0 Public DomainWhile cancers often originate from mutations and other alterations of cells' DNA, researchers in the Bernstein Laboratory at D

Updated on: January 04,2024

Origins of glioma brain cancer found to be in the epigenome

byDana-Farber Cancer InstituteCredit: Unsplash/CC0 Public DomainWhile cancers often originate from mutations and other alterations of cells' DNA, researchers in the Bernstein Laboratory at D

Updated on:January 04,2024