Genes activated in metastasis also drive the first stages of tumour growth

by Institute for Research in Biomedicine (IRB Barcelona)The overexpression of the gene Serpent in the Drosophila wing causes permanent overgrowth and it is sufficient to promote tumour developmen

Updated on: March 01,2024 19

Genes activated in metastasis also drive the first stages of tumour growth

by Institute for Research in Biomedicine (IRB Barcelona)The overexpression of the gene Serpent in the Drosophila wing causes permanent overgrowth and it is sufficient to promote tumour developmen

Updated on:March 01,2024 19

Genetic breast cancer study alters guidelines in Sweden

by Lund UniversityCredit: Pixabay/CC0 Public DomainBRCA1 and BRCA2 are well-known breast cancer genes associated with a significantly increased risk of hereditary breast and ovarian cancer. Howev

Updated on: February 01,2024 14

Genetic breast cancer study alters guidelines in Sweden

by Lund UniversityCredit: Pixabay/CC0 Public DomainBRCA1 and BRCA2 are well-known breast cancer genes associated with a significantly increased risk of hereditary breast and ovarian cancer. Howev

Updated on:February 01,2024 14

BMI's relation to cancer therapy mortality risks not so straightforward, study finds

byOsaka Metropolitan UniversityFor non-small cell lung cancer treatment, immunotherapy seems to pose less risk for persons under a certain BMI, while conventional chemotherapy appears optimal fo

Updated on: September 27,2024 0

BMI's relation to cancer therapy mortality risks not so straightforward, study finds

byOsaka Metropolitan UniversityFor non-small cell lung cancer treatment, immunotherapy seems to pose less risk for persons under a certain BMI, while conventional chemotherapy appears optimal fo

Updated on:September 27,2024 0

'Synthetic immune niche' approach enhances T-cell proliferation without compromising cancer-killing ability

byWeizmann Institute of ScienceComparison of the significant differences in gene expression profiles between DC-activated cells (orange dots) and bead-activated cells (black dots) on their '

Updated on: September 28,2024 0

'Synthetic immune niche' approach enhances T-cell proliferation without compromising cancer-killing ability

byWeizmann Institute of ScienceComparison of the significant differences in gene expression profiles between DC-activated cells (orange dots) and bead-activated cells (black dots) on their '

Updated on:September 28,2024 0

Immunotherapy was meant to defeat cancer—what happened to the great promise?

by Jonathan Fisher,The ConversationCredit: Ivan Samkov from PexelsIn 1893, theAmerican Journal of the Medical Sciencesreported on 10 patients whose large and hitherto incurable cance

Updated on: November 10,2024 0

Immunotherapy was meant to defeat cancer—what happened to the great promise?

by Jonathan Fisher,The ConversationCredit: Ivan Samkov from PexelsIn 1893, theAmerican Journal of the Medical Sciencesreported on 10 patients whose large and hitherto incurable cance

Updated on:November 10,2024 0

Depression linked to deadly inflammation in lung cancer patients

by Jeff Grabmeier,The Ohio State UniversityKaplan Meier survival curve for NSCLC patients stratified by NLR systemic inflammation, NLR < 5 and NLR ≥ 5 (n = 184), showing worse survival probab

Updated on: January 30,2024 11

Depression linked to deadly inflammation in lung cancer patients

by Jeff Grabmeier,The Ohio State UniversityKaplan Meier survival curve for NSCLC patients stratified by NLR systemic inflammation, NLR < 5 and NLR ≥ 5 (n = 184), showing worse survival probab

Updated on:January 30,2024 11

Boosting the effects of a particular microRNA may benefit patients with cervical cancer

by WileyHigh grade dysplasia (carcinoma in situ) in the uterine cervix. The abnormal epithelium is extending into a mucus gland to the left of centre. This disease can progress to invasive cancer

Updated on: February 18,2024 19

Boosting the effects of a particular microRNA may benefit patients with cervical cancer

by WileyHigh grade dysplasia (carcinoma in situ) in the uterine cervix. The abnormal epithelium is extending into a mucus gland to the left of centre. This disease can progress to invasive cancer

Updated on:February 18,2024 19

Drug suppresses spread of breast cancer caused by stem-like cells

by University of California - San DiegoA rare-stem like tumor cell, which plays a critical role in the spread of breast cancer, is identified with immunostaining for the β3 integrin subunit (blue

Updated on: March 12,2024 17

Drug suppresses spread of breast cancer caused by stem-like cells

by University of California - San DiegoA rare-stem like tumor cell, which plays a critical role in the spread of breast cancer, is identified with immunostaining for the β3 integrin subunit (blue

Updated on:March 12,2024 17

New bioinformatics tool to identify chromosomal alterations in tumor cells

by University of BarcelonaRepresentative output image generated by QATS in which two toroidal nuclei (in magenta) and four micronuclei (in green) were identified. Credit:Bioinformatics&nbsp

Updated on: March 30,2024 0

New bioinformatics tool to identify chromosomal alterations in tumor cells

by University of BarcelonaRepresentative output image generated by QATS in which two toroidal nuclei (in magenta) and four micronuclei (in green) were identified. Credit:Bioinformatics&nbsp

Updated on:March 30,2024 0

New review on p53 biology and reactivation in blood cancers

byKarolinska InstitutetA simplified scheme of p53 regulation in cells upon stress and the drugs currently evaluated in clinical trials for p53 reactivation for improved therapy in MDS and AML. C

Updated on: March 30,2024 0

New review on p53 biology and reactivation in blood cancers

byKarolinska InstitutetA simplified scheme of p53 regulation in cells upon stress and the drugs currently evaluated in clinical trials for p53 reactivation for improved therapy in MDS and AML. C

Updated on:March 30,2024 0

Drug makes tumors more susceptible to chemo

by Massachusetts Institute of TechnologyStructure of the complex containing Rev1 and JH-RE-06. The two copies of the Rev1 protein are shown in dark and light blue, while the small molecule JH-RE-

Updated on: May 25,2024 3

Drug makes tumors more susceptible to chemo

by Massachusetts Institute of TechnologyStructure of the complex containing Rev1 and JH-RE-06. The two copies of the Rev1 protein are shown in dark and light blue, while the small molecule JH-RE-

Updated on:May 25,2024 3

Pathway tied to cancer-driving genome alterations identified

byUTSouthwestern Medical CenterThese images show examples of mitotic chromosome spreads from human cancer cells containing a shattered chromosome (left panel) or extrachromosomal DNA (midd

Updated on: September 27,2024 0

Pathway tied to cancer-driving genome alterations identified

byUTSouthwestern Medical CenterThese images show examples of mitotic chromosome spreads from human cancer cells containing a shattered chromosome (left panel) or extrachromosomal DNA (midd

Updated on:September 27,2024 0