Development and application of competing risks and multi-state models in cancer epidemiology

byKarolinska InstitutetCredit: Unsplash/CC0 Public DomainCompeting risks and multi-state models allow us to study complex disease settings and answer composite research questions and should be u

Updated on: December 18,2023

Development and application of competing risks and multi-state models in cancer epidemiology

byKarolinska InstitutetCredit: Unsplash/CC0 Public DomainCompeting risks and multi-state models allow us to study complex disease settings and answer composite research questions and should be u

Updated on:December 18,2023

Two genes slow down the development of intestinal tumors

byThe Francis Crick InstituteImage of two intestinaltumours, one a control (top) and one with the genes NEDD4 and NEDD4L deleted (bottom). Credit: The Francis Crick InstituteBenign i

Updated on: December 22,2023

Two genes slow down the development of intestinal tumors

byThe Francis Crick InstituteImage of two intestinaltumours, one a control (top) and one with the genes NEDD4 and NEDD4L deleted (bottom). Credit: The Francis Crick InstituteBenign i

Updated on:December 22,2023

Novel treatment regimen for FLT3-mutated acute myeloid leukemia shows promise in new study

by Roswell Park Comprehensive Cancer CenterAcute myelocytic leukemia (AML). Credit: Unsplash/CC0 Public DomainUp to 30% of patients newly diagnosed with acute myeloid leukemia (AML) have an FLT3 gene

Updated on: March 22,2024

Novel treatment regimen for FLT3-mutated acute myeloid leukemia shows promise in new study

by Roswell Park Comprehensive Cancer CenterAcute myelocytic leukemia (AML). Credit: Unsplash/CC0 Public DomainUp to 30% of patients newly diagnosed with acute myeloid leukemia (AML) have an FLT3 gene

Updated on:March 22,2024

A top-down study of isogenic human non-metastatic and metastatic colorectal cancer cell lines

by Bob Yirka , Medical XpressSchematic of the experimental design. (A) Schematic design of the TDP study of metastatic (SW620) and nonmetastatic (SW480) CRC cells using CZE-ESI-MS/MS and LC-CZE-ESI-MS

Updated on: December 20,2023

A top-down study of isogenic human non-metastatic and metastatic colorectal cancer cell lines

by Bob Yirka , Medical XpressSchematic of the experimental design. (A) Schematic design of the TDP study of metastatic (SW620) and nonmetastatic (SW480) CRC cells using CZE-ESI-MS/MS and LC-CZE-ESI-MS

Updated on:December 20,2023

Rituximab Maintenance Effective for Autoimmune Cytopenias

August 2023Thomas R. CollinsPatients with autoimmune cytopenias had longer durations of response after induction treatment with rituximab when rituximab was continued as maintenance therapy compared w

Updated on: February 18,2024

Rituximab Maintenance Effective for Autoimmune Cytopenias

August 2023Thomas R. CollinsPatients with autoimmune cytopenias had longer durations of response after induction treatment with rituximab when rituximab was continued as maintenance therapy compared w

Updated on:February 18,2024

Novel treatment shows promise against rare cancer in kids

by Carla K. JohnsonThis December 1993 microscope photo provided by the National Cancer Institute shows a typical neuroblastoma with rosette formation. In a study published Wednesday, April 5, 2023, in

Updated on: March 25,2024

Novel treatment shows promise against rare cancer in kids

by Carla K. JohnsonThis December 1993 microscope photo provided by the National Cancer Institute shows a typical neuroblastoma with rosette formation. In a study published Wednesday, April 5, 2023, in

Updated on:March 25,2024

Free tool simplifies cancer research

byKarolinska InstitutetCredit: CC0 Public DomainEvery cell contains a vast number of proteins, each of which has a specific function, for example, as a receptor for another molecule or an enzyme

Updated on: December 22,2023

Free tool simplifies cancer research

byKarolinska InstitutetCredit: CC0 Public DomainEvery cell contains a vast number of proteins, each of which has a specific function, for example, as a receptor for another molecule or an enzyme

Updated on:December 22,2023

FDA approves new treatment for advanced melanoma

by Robin FosterThe U.S. Food and Drug Administration has approved a novel treatment for advanced melanoma, the most deadly form of skin cancer.Amtagvi, made by Iovance Biotherapeutics Inc., becomes th

Updated on: March 22,2024

FDA approves new treatment for advanced melanoma

by Robin FosterThe U.S. Food and Drug Administration has approved a novel treatment for advanced melanoma, the most deadly form of skin cancer.Amtagvi, made by Iovance Biotherapeutics Inc., becomes th

Updated on:March 22,2024

New model explains how our immune system sometimes helps cancer spread

by Katie Willis,University of AlbertaCredit: CC0 Public DomainMathematicians at the University of Alberta have developed a model that explains how the immune system interacts with cancer—and in

Updated on: December 22,2023

New model explains how our immune system sometimes helps cancer spread

by Katie Willis,University of AlbertaCredit: CC0 Public DomainMathematicians at the University of Alberta have developed a model that explains how the immune system interacts with cancer—and in

Updated on:December 22,2023

Energy stress triggers PFKL-dependent lipid droplet-mitochondria tethering and β-oxidation to support tumor growth

Updated on: September 15,2024

Energy stress triggers PFKL-dependent lipid droplet-mitochondria tethering and β-oxidation to support tumor growth

Updated on:September 15,2024

Combining cholesterol-lowering statins with existing cancer drug shows potent effect against breast cancer subtype

by Katie Brace,Beth Israel Deaconess Medical CenterTN/ER-low PDOs are sensitive to combination AZD5363 and pitavastatin. A panel of breast cancer PDOs were treated with DMSO, 1 µM AZD5363, 5 µM

Updated on: August 26,2024

Combining cholesterol-lowering statins with existing cancer drug shows potent effect against breast cancer subtype

by Katie Brace,Beth Israel Deaconess Medical CenterTN/ER-low PDOs are sensitive to combination AZD5363 and pitavastatin. A panel of breast cancer PDOs were treated with DMSO, 1 µM AZD5363, 5 µM

Updated on:August 26,2024

New Study Uncovers Mechanisms Behind LKB1 Mutation-Driven Resistance to Immunotherapy in Lung Cancer

Updated on: July 17,2024

New Study Uncovers Mechanisms Behind LKB1 Mutation-Driven Resistance to Immunotherapy in Lung Cancer

Updated on:July 17,2024