Combining cholesterol-lowering statins with existing cancer drug shows potent effect against breast cancer subtype

by Katie Brace,Beth Israel Deaconess Medical CenterTN/ER-low PDOs are sensitive to combination AZD5363 and pitavastatin. A panel of breast cancer PDOs were treated with DMSO, 1 µM AZD5363, 5 µM

Updated on: August 26,2024

Combining cholesterol-lowering statins with existing cancer drug shows potent effect against breast cancer subtype

by Katie Brace,Beth Israel Deaconess Medical CenterTN/ER-low PDOs are sensitive to combination AZD5363 and pitavastatin. A panel of breast cancer PDOs were treated with DMSO, 1 µM AZD5363, 5 µM

Updated on:August 26,2024

Longer wait for some forms of cancer diagnosis for Black and Asian patients

byUniversity of ExeterSite-specific box and Whisker plots showing ethnic differences in the number of days to diagnosis (lower adjacent value, 25th, 50th, and 75th centiles, and upper adjacent v

Updated on: December 24,2023

Longer wait for some forms of cancer diagnosis for Black and Asian patients

byUniversity of ExeterSite-specific box and Whisker plots showing ethnic differences in the number of days to diagnosis (lower adjacent value, 25th, 50th, and 75th centiles, and upper adjacent v

Updated on:December 24,2023

New tool combines evolution and AI to predict prostate cancer recurrence more than a decade ahead

New tool combines evolution and AI to predict prostate cancer recurrence more than a decade aheadbyInstitute of Cancer ResearchStudy design. Credit:Nature Cancer(2024). DOI: 10.1038/

Updated on: July 17,2024

New tool combines evolution and AI to predict prostate cancer recurrence more than a decade ahead

New tool combines evolution and AI to predict prostate cancer recurrence more than a decade aheadbyInstitute of Cancer ResearchStudy design. Credit:Nature Cancer(2024). DOI: 10.1038/

Updated on:July 17,2024

Machine learning-triggered reminders improve end-of-life care for patients with cancer

byPerelman School of Medicine at the University of PennsylvaniaCredit: Pixabay/CC0 Public DomainElectronic nudges delivered to health care clinicians based on a machine learning algorithm that p

Updated on: December 25,2023

Machine learning-triggered reminders improve end-of-life care for patients with cancer

byPerelman School of Medicine at the University of PennsylvaniaCredit: Pixabay/CC0 Public DomainElectronic nudges delivered to health care clinicians based on a machine learning algorithm that p

Updated on:December 25,2023

FDA approves new treatment for advanced melanoma

by Robin FosterThe U.S. Food and Drug Administration has approved a novel treatment for advanced melanoma, the most deadly form of skin cancer.Amtagvi, made by Iovance Biotherapeutics Inc., becomes th

Updated on: March 22,2024

FDA approves new treatment for advanced melanoma

by Robin FosterThe U.S. Food and Drug Administration has approved a novel treatment for advanced melanoma, the most deadly form of skin cancer.Amtagvi, made by Iovance Biotherapeutics Inc., becomes th

Updated on:March 22,2024

Assessing clinical implementation of past standards for interpretation and reporting of sequence variants in cancer

by Association for Molecular PathologyAMP/ASCO/CAP Somatic Variants Guideline Implementation Survey—Selected Results. Panel A: Q1: Have you implemented the AMP/ASCO/CAP somatic variant classification

Updated on: January 02,2024

Assessing clinical implementation of past standards for interpretation and reporting of sequence variants in cancer

by Association for Molecular PathologyAMP/ASCO/CAP Somatic Variants Guideline Implementation Survey—Selected Results. Panel A: Q1: Have you implemented the AMP/ASCO/CAP somatic variant classification

Updated on:January 02,2024

A solid vaccine for liquid tumors

byHarvard UniversityCredit: CC0 Public DomainAcute myeloid leukemia (AML) is a deadly blood cancer that originates in the bone marrow and kills most of its victims within five years. Chemotherap

Updated on: December 20,2023

A solid vaccine for liquid tumors

byHarvard UniversityCredit: CC0 Public DomainAcute myeloid leukemia (AML) is a deadly blood cancer that originates in the bone marrow and kills most of its victims within five years. Chemotherap

Updated on:December 20,2023

Measuring tumor infiltrating lymphocytes predicts long term outcomes for type of early breast cancer

byQueen Mary, University of LondonBenefit of radiotherapy in preventing IBE by CPath TIL categories. Credit:The Lancet Digital Health(2024). DOI: 10.1016/S2589-7500(24)00116-XResearc

Updated on: July 11,2024

Measuring tumor infiltrating lymphocytes predicts long term outcomes for type of early breast cancer

byQueen Mary, University of LondonBenefit of radiotherapy in preventing IBE by CPath TIL categories. Credit:The Lancet Digital Health(2024). DOI: 10.1016/S2589-7500(24)00116-XResearc

Updated on:July 11,2024

Scientists to improve cancer treatment effectiveness

byNational Research Nuclear UniversityCredit: CC0 Public DomainTogether with researchers from the University of Nantes and the University of Reims Champagne-Ardenne in France, experts from the N

Updated on: December 18,2023

Scientists to improve cancer treatment effectiveness

byNational Research Nuclear UniversityCredit: CC0 Public DomainTogether with researchers from the University of Nantes and the University of Reims Champagne-Ardenne in France, experts from the N

Updated on:December 18,2023

Gut microbes implicated in bladder cancer

byEuropean Molecular Biology LaboratoryA science illustrator depicts how the carcinogen BBN (left) is affected by gut bacteria and then metabolized to BCPN (right) and distributed in the body, l

Updated on: August 27,2024

Gut microbes implicated in bladder cancer

byEuropean Molecular Biology LaboratoryA science illustrator depicts how the carcinogen BBN (left) is affected by gut bacteria and then metabolized to BCPN (right) and distributed in the body, l

Updated on:August 27,2024

Entering the golden age for antibody-drug conjugates in gynecologic cancer

by Impact Journals LLCCredit: Pixabay/CC0 Public DomainIn an editorial, published inOncosciencetitled, "Entering the golden age for antibody-drug conjugates in gynecologic cancer,&quo

Updated on: July 17,2024

Entering the golden age for antibody-drug conjugates in gynecologic cancer

by Impact Journals LLCCredit: Pixabay/CC0 Public DomainIn an editorial, published inOncosciencetitled, "Entering the golden age for antibody-drug conjugates in gynecologic cancer,&quo

Updated on:July 17,2024

Discovery could improve MDS cancer treatment

by Cold Spring Harbor LaboratoryImmature blood cells (stained purple) do not divide into enough functioning red blood cells when defective. Researchers have discovered how to stop the protein sig

Updated on: April 14,2024

Discovery could improve MDS cancer treatment

by Cold Spring Harbor LaboratoryImmature blood cells (stained purple) do not divide into enough functioning red blood cells when defective. Researchers have discovered how to stop the protein sig

Updated on:April 14,2024