Novel combination therapy has similar response rates to chemotherapy for high-risk luminal B breast cancer

byAmerican Association for Cancer ResearchNeoadjuvant treatment with the CDK4/6 inhibitor ribociclib (Kisqali) and the aromatase inhibitor letrozole (Femara) produced response rates similar to m

Updated on: December 22,2023

Novel combination therapy has similar response rates to chemotherapy for high-risk luminal B breast cancer

byAmerican Association for Cancer ResearchNeoadjuvant treatment with the CDK4/6 inhibitor ribociclib (Kisqali) and the aromatase inhibitor letrozole (Femara) produced response rates similar to m

Updated on:December 22,2023

Cigarette smoke and HPV have synergistic effects on cells, heightening the risk of head and neck cancer

by Julia Moióli,FAPESPHPV16 E6/E7 induces SOD2 expression in oral cells. (A) HPV16 E6/E7 transcripts were evaluated by RT-PCR in SCC143V and SCC143E6/E7 cells; β-actin was used as the control. (

Updated on: January 10,2024

Cigarette smoke and HPV have synergistic effects on cells, heightening the risk of head and neck cancer

by Julia Moióli,FAPESPHPV16 E6/E7 induces SOD2 expression in oral cells. (A) HPV16 E6/E7 transcripts were evaluated by RT-PCR in SCC143V and SCC143E6/E7 cells; β-actin was used as the control. (

Updated on:January 10,2024

Shutting down backup genes leads to cancer remission in mice

by Jim Lynch,University of MichiganAbhinav Achreja, PhD, Research Fellow at the University of Michigan Biomedical Engineering and Deepak Nagrath, Ph.D. Associate Professor of Biomedical Engineer

Updated on: December 22,2023

Shutting down backup genes leads to cancer remission in mice

by Jim Lynch,University of MichiganAbhinav Achreja, PhD, Research Fellow at the University of Michigan Biomedical Engineering and Deepak Nagrath, Ph.D. Associate Professor of Biomedical Engineer

Updated on:December 22,2023

Scientists reveal how different cancer cells 'team up' to help incurable childhood brain tumor spread

byInstitute of Cancer ResearchSimulating cellular invasion (A) Illustration of simulation flow. (B) Summary statistics used to measure invasion: (i)traveling-wave solution to reaction-diff

Updated on: December 27,2023

Scientists reveal how different cancer cells 'team up' to help incurable childhood brain tumor spread

byInstitute of Cancer ResearchSimulating cellular invasion (A) Illustration of simulation flow. (B) Summary statistics used to measure invasion: (i)traveling-wave solution to reaction-diff

Updated on:December 27,2023

MRD Could Play Role in Predicting Post-ASCT Outcomes in Myeloma

September 9, 2021Darlene Dobkowski, MAFor patients with myeloma have undergone an autologous stem cell transplant and are currently on maintenance therapy with lenalidomide, minimal residual disease m

Updated on: October 24,2023

MRD Could Play Role in Predicting Post-ASCT Outcomes in Myeloma

September 9, 2021Darlene Dobkowski, MAFor patients with myeloma have undergone an autologous stem cell transplant and are currently on maintenance therapy with lenalidomide, minimal residual disease m

Updated on:October 24,2023

Conversation tool to help cancer patients with treatment choices

byLeiden UniversityCredit: Pixabay/CC0 Public DomainResearchers at the Leiden Institute of Advanced Computer Science (LIACS) are collaborating on the development of a conversation tool for patie

Updated on: December 21,2023

Conversation tool to help cancer patients with treatment choices

byLeiden UniversityCredit: Pixabay/CC0 Public DomainResearchers at the Leiden Institute of Advanced Computer Science (LIACS) are collaborating on the development of a conversation tool for patie

Updated on:December 21,2023

Stage and receptor status can indicate a breast cancer survivor's risk of recurrence

Updated on: December 22,2023

Stage and receptor status can indicate a breast cancer survivor's risk of recurrence

Updated on:December 22,2023

Treatment of aggressive breast cancer improved by immunotherapy-chemotherapy combination

byUniversity of Pittsburgh Schools of the Health SciencesLeisha Emens, M.D., Ph.D., co-leader of the UPMC Hillman Cancer Immunology and Immunotherapy Program. Credit: UPMCPatients with an aggres

Updated on: December 18,2023

Treatment of aggressive breast cancer improved by immunotherapy-chemotherapy combination

byUniversity of Pittsburgh Schools of the Health SciencesLeisha Emens, M.D., Ph.D., co-leader of the UPMC Hillman Cancer Immunology and Immunotherapy Program. Credit: UPMCPatients with an aggres

Updated on:December 18,2023

Viewpoint: FDA needs to ensure that information on dense breast notifications are clear and understandable to all

byBoston University School of MedicineCredit: Pixabay/CC0 Public DomainYou are among the women who dutifully gets an annual mammogram. Year after year, the results are "normal." But af

Updated on: December 23,2023

Viewpoint: FDA needs to ensure that information on dense breast notifications are clear and understandable to all

byBoston University School of MedicineCredit: Pixabay/CC0 Public DomainYou are among the women who dutifully gets an annual mammogram. Year after year, the results are "normal." But af

Updated on:December 23,2023

Entrectinib effective, well-tolerated against ROS1 and NTRK lung cancers, especially with brain metastases

by Garth Sundem,CU Anschutz Medical CampusRobert C. Doebele, MD, PhD. Credit: CU Anschutz Medical CampusPooled analysis of three phase 1 and 2 clinical trials published online ahead of print in

Updated on: December 22,2023

Entrectinib effective, well-tolerated against ROS1 and NTRK lung cancers, especially with brain metastases

by Garth Sundem,CU Anschutz Medical CampusRobert C. Doebele, MD, PhD. Credit: CU Anschutz Medical CampusPooled analysis of three phase 1 and 2 clinical trials published online ahead of print in

Updated on:December 22,2023

A promising treatment for ovarian cancer

by Erin Matthews,Canadian Light SourceOvary. Credit: Public DomainOver 20,000 women across the U.S. and Canada are diagnosed with ovarian cancer annually. The symptoms of this disease are often

Updated on: March 12,2024

A promising treatment for ovarian cancer

by Erin Matthews,Canadian Light SourceOvary. Credit: Public DomainOver 20,000 women across the U.S. and Canada are diagnosed with ovarian cancer annually. The symptoms of this disease are often

Updated on:March 12,2024

COVID-19 antiviral treatment should be taken for longer, says study

by University College LondonViral and spike antibody dynamics in molnupiravir (purple) and Usual Care (gray) arms. a) Median viral load ±95%CI with time, below limit of quantification (BLOQ) meas

Updated on: May 11,2024

COVID-19 antiviral treatment should be taken for longer, says study

by University College LondonViral and spike antibody dynamics in molnupiravir (purple) and Usual Care (gray) arms. a) Median viral load ±95%CI with time, below limit of quantification (BLOQ) meas

Updated on:May 11,2024