How two 1990s discoveries have led to (some) cured cancers, and a Nobel Prize

by Craig Gedye,The ConversationCredit: CC0 Public DomainThis year's award of theNobel Prize for Physiology and Medicineto James P. Allison and Tasuku Honjo, for their work in the

Updated on: March 14,2024

How two 1990s discoveries have led to (some) cured cancers, and a Nobel Prize

by Craig Gedye,The ConversationCredit: CC0 Public DomainThis year's award of theNobel Prize for Physiology and Medicineto James P. Allison and Tasuku Honjo, for their work in the

Updated on:March 14,2024

Pancreatic cancer cells secrete signal that sabotages immune attack on tumors

byNYU Langone HealthMouse pancreatic tumor cells (red) produce the signaling protein IL-1β (green) to support cancer growth by suppressing the immune system. Credit: NYU Grossman School of Medic

Updated on: December 22,2023

Pancreatic cancer cells secrete signal that sabotages immune attack on tumors

byNYU Langone HealthMouse pancreatic tumor cells (red) produce the signaling protein IL-1β (green) to support cancer growth by suppressing the immune system. Credit: NYU Grossman School of Medic

Updated on:December 22,2023

Obesity is a risk factor for cardiotoxicity in chemotherapy-treated patients with breast cancer

byPublic Library of ScienceObesity is associated with a three-fold increased risk of cardiotoxicity in chemotherapy-treated patients with early-stage breast cancer, regardless of other predictor

Updated on: December 22,2023

Obesity is a risk factor for cardiotoxicity in chemotherapy-treated patients with breast cancer

byPublic Library of ScienceObesity is associated with a three-fold increased risk of cardiotoxicity in chemotherapy-treated patients with early-stage breast cancer, regardless of other predictor

Updated on:December 22,2023

Response to neoadjuvant chemo for breast cancer varies by sex

Both proportions and odds of pathologic complete response (pCR) to neoadjuvant chemotherapy (NAC) are numerically lower in men with breast cancer (BC) versus women with BC for each tumor subtype, acco

Updated on: December 20,2023

Response to neoadjuvant chemo for breast cancer varies by sex

Both proportions and odds of pathologic complete response (pCR) to neoadjuvant chemotherapy (NAC) are numerically lower in men with breast cancer (BC) versus women with BC for each tumor subtype, acco

Updated on:December 20,2023

NELSON trial protocol more sensitive than NLST and may increase the benefits of lung cancer screening

by International Association for the Study of Lung CancerCredit: Pixabay/CC0 Public DomainThe protocol used to screen and detect lung cancer in the NELSON Trial is more sensitive than the protocol use

Updated on: December 18,2023

NELSON trial protocol more sensitive than NLST and may increase the benefits of lung cancer screening

by International Association for the Study of Lung CancerCredit: Pixabay/CC0 Public DomainThe protocol used to screen and detect lung cancer in the NELSON Trial is more sensitive than the protocol use

Updated on:December 18,2023

Unraveling predisposition in bilateral Wilms tumor

bySt. Jude Children's Research HospitalSummary of Proposed Mechanisms for Bilateral Wilms tumor development. Credit:Nature Communications(2023). DOI: 10.1038/s41467-023-43730-0Ch

Updated on: December 30,2023

Unraveling predisposition in bilateral Wilms tumor

bySt. Jude Children's Research HospitalSummary of Proposed Mechanisms for Bilateral Wilms tumor development. Credit:Nature Communications(2023). DOI: 10.1038/s41467-023-43730-0Ch

Updated on:December 30,2023

Physical exercise prevents nerve damage during chemotherapy, sports scientist shows

byUniversity of BaselSports therapy to combat side effects: Fiona Streckmann with a patient during a neurological examination. A tuning fork is used to test vibration sensation, which can be alt

Updated on: July 08,2024

Physical exercise prevents nerve damage during chemotherapy, sports scientist shows

byUniversity of BaselSports therapy to combat side effects: Fiona Streckmann with a patient during a neurological examination. A tuning fork is used to test vibration sensation, which can be alt

Updated on:July 08,2024

How cancer cells die: Scientists explore new pathways of pyroptosis, killer kin of apoptosis

by Delthia Ricks , Medical XpressLymphoid BLaER1 cells undergo PANX1-dominant lysis. (A to C) BLaER1 cells were treated with topoisomerase poisons doxorubicin (2 μM) or etoposide (50 μM) for 24 hours.

Updated on: December 18,2023

How cancer cells die: Scientists explore new pathways of pyroptosis, killer kin of apoptosis

by Delthia Ricks , Medical XpressLymphoid BLaER1 cells undergo PANX1-dominant lysis. (A to C) BLaER1 cells were treated with topoisomerase poisons doxorubicin (2 μM) or etoposide (50 μM) for 24 hours.

Updated on:December 18,2023

How dangerous is it for lung cancer patients to skip radiation treatments?

by Cara MurezAs doctors work toward developing more personalized cancer care, a new study looks at whether lung cancer patients can miss a few days of radiation treatment and make them up with a highe

Updated on: December 22,2023

How dangerous is it for lung cancer patients to skip radiation treatments?

by Cara MurezAs doctors work toward developing more personalized cancer care, a new study looks at whether lung cancer patients can miss a few days of radiation treatment and make them up with a highe

Updated on:December 22,2023

Olaparib maintenance extends PFS by estimated three years in advanced ovarian cancer

byEuropean Society for Medical OncologyTwo-year maintenance therapy with olaparib, a PARP (poly ADP ribose polymerase) inhibitor, olaparib, led to a substantial, unprecedented improvement in pro

Updated on: December 18,2023

Olaparib maintenance extends PFS by estimated three years in advanced ovarian cancer

byEuropean Society for Medical OncologyTwo-year maintenance therapy with olaparib, a PARP (poly ADP ribose polymerase) inhibitor, olaparib, led to a substantial, unprecedented improvement in pro

Updated on:December 18,2023

GZ17-6.02 with bexarotene kills mycosis fungoides cells: Study

by Impact Journals LLCCombined macroautophagy and CD95 death receptor signaling facilitate additional tumor cell killing by GZ17-6.02. Credit: 2024 Booth et al.A new research paper titled "GZ17-6

Updated on: May 26,2024

GZ17-6.02 with bexarotene kills mycosis fungoides cells: Study

by Impact Journals LLCCombined macroautophagy and CD95 death receptor signaling facilitate additional tumor cell killing by GZ17-6.02. Credit: 2024 Booth et al.A new research paper titled "GZ17-6

Updated on:May 26,2024

Prozac fights deadly childhood brain cancer

by Hayley Jarvis,Brunel UniversityKiller T cells surround a cancer cell. Credit: NIHThe anti-depressant drug Prozac could be used to tackle one of the deadliest childhood tumours and possibly ot

Updated on: December 22,2023

Prozac fights deadly childhood brain cancer

by Hayley Jarvis,Brunel UniversityKiller T cells surround a cancer cell. Credit: NIHThe anti-depressant drug Prozac could be used to tackle one of the deadliest childhood tumours and possibly ot

Updated on:December 22,2023