Researchers identify the 'broken gate' causing unstoppable brain signals in severe childhood epilepsy

by Florey Institute of Neuroscience and Mental Health2D transmembrane topology of the wild-type (WT) Nav1.2 channel showing 27 domains DI−DIV and amino acid residues N1662 (cytosolic side of S5DIV) an

Updated on: August 03,2024

Researchers identify the 'broken gate' causing unstoppable brain signals in severe childhood epilepsy

by Florey Institute of Neuroscience and Mental Health2D transmembrane topology of the wild-type (WT) Nav1.2 channel showing 27 domains DI−DIV and amino acid residues N1662 (cytosolic side of S5DIV) an

Updated on:August 03,2024

The path to Parkinson's disease: All roads lead to the nigrosome

by Tiziano Balzano , Medical XpressThe nigrosome has an intricate and dense network of highways and streets, representing its rich vascularization. This dense network makes the nigrosome a major inter

Updated on: July 05,2024

The path to Parkinson's disease: All roads lead to the nigrosome

by Tiziano Balzano , Medical XpressThe nigrosome has an intricate and dense network of highways and streets, representing its rich vascularization. This dense network makes the nigrosome a major inter

Updated on:July 05,2024

New discovery could help treat a rare and severe form of amyloidosis

byWileyPET scan of a human brain with Alzheimer's disease. Credit: public domainIn people with a rare condition called light chain amyloidosis, light chain proteins—which are a component of

Updated on: July 11,2024

New discovery could help treat a rare and severe form of amyloidosis

byWileyPET scan of a human brain with Alzheimer's disease. Credit: public domainIn people with a rare condition called light chain amyloidosis, light chain proteins—which are a component of

Updated on:July 11,2024

A new biomarker makes it easier to distinguish between Alzheimer's and primary tauopathy

byLudwig Maximilian University of MunichDiscriminatory power of tau binding and p-tau between pairs of groups. Credit:Alzheimer's & Dementia(2024). DOI:10.1002/alz.14185. htt

Updated on: September 23,2024

A new biomarker makes it easier to distinguish between Alzheimer's and primary tauopathy

byLudwig Maximilian University of MunichDiscriminatory power of tau binding and p-tau between pairs of groups. Credit:Alzheimer's & Dementia(2024). DOI:10.1002/alz.14185. htt

Updated on:September 23,2024

Key mechanisms in asymptomatic Alzheimer's disease brains offer potential protection against cognitive decline

byIndiana UniversityMicroglia and astrocytic coverage around compact, intermediate, and filamentous amyloid plaques between AD and AsymAD cases. Credit:Acta Neuropathologica(2024). D

Updated on: October 21,2024

Key mechanisms in asymptomatic Alzheimer's disease brains offer potential protection against cognitive decline

byIndiana UniversityMicroglia and astrocytic coverage around compact, intermediate, and filamentous amyloid plaques between AD and AsymAD cases. Credit:Acta Neuropathologica(2024). D

Updated on:October 21,2024

Mild traumatic brain injury causes long-term damage in mice

by WileyA newAnnals of Clinical and Translational Neurologystudy in mice found that mild traumatic brain injury (TBI) can precipitate not only acute damage but also a lifelong degener

Updated on: March 07,2024

Mild traumatic brain injury causes long-term damage in mice

by WileyA newAnnals of Clinical and Translational Neurologystudy in mice found that mild traumatic brain injury (TBI) can precipitate not only acute damage but also a lifelong degener

Updated on:March 07,2024

Scientists identify possible way to block muscle fatigue in long COVID, other diseases

byWashington University School of MedicineResearch from Washington University School of Medicine in St. Louis reveals how brain inflammation triggers extreme muscle weakness across several disea

Updated on: July 17,2024

Scientists identify possible way to block muscle fatigue in long COVID, other diseases

byWashington University School of MedicineResearch from Washington University School of Medicine in St. Louis reveals how brain inflammation triggers extreme muscle weakness across several disea

Updated on:July 17,2024

Breathing coordinates brain rhythms for memory consolidation during sleep

Breathing coordinates brain rhythms for memory consolidation during sleepbyNorthwestern UniversityCorresponding author Andrew Sheriff looks at a computer monitor in a lab. Credit: Northwestern U

Updated on: January 15,2025

Breathing coordinates brain rhythms for memory consolidation during sleep

Breathing coordinates brain rhythms for memory consolidation during sleepbyNorthwestern UniversityCorresponding author Andrew Sheriff looks at a computer monitor in a lab. Credit: Northwestern U

Updated on:January 15,2025

Proteomic profile study reveals signatures for distinguishing different forms of Alzheimer's disease

by Justin Jackson , Medical XpressCredit: Pixabay/CC0 Public DomainResearchers at Washington University School of Medicine in St. Louis have identified proteomic changes associated with forms of Alzhe

Updated on: May 20,2024

Proteomic profile study reveals signatures for distinguishing different forms of Alzheimer's disease

by Justin Jackson , Medical XpressCredit: Pixabay/CC0 Public DomainResearchers at Washington University School of Medicine in St. Louis have identified proteomic changes associated with forms of Alzhe

Updated on:May 20,2024

Mouse study finds sex-based differences in how brains handle threats

Mouse study finds sex-based differences in how brains handle threatsby Claire Loewen,McGill UniversityMales and females similarly acquire threat discrimination. Credit:Nature Neuroscience&

Updated on: September 23,2024

Mouse study finds sex-based differences in how brains handle threats

Mouse study finds sex-based differences in how brains handle threatsby Claire Loewen,McGill UniversityMales and females similarly acquire threat discrimination. Credit:Nature Neuroscience&

Updated on:September 23,2024

Highly awaited Alzheimer's drug hit by delays

Credit: Unsplash/CC0 Public DomainEli Lilly's highly anticipated Alzheimer's drug has been held back for further review by regulators, the US pharmaceutical giant said Friday, in a blow for pa

Updated on: March 19,2024

Highly awaited Alzheimer's drug hit by delays

Credit: Unsplash/CC0 Public DomainEli Lilly's highly anticipated Alzheimer's drug has been held back for further review by regulators, the US pharmaceutical giant said Friday, in a blow for pa

Updated on:March 19,2024

Dementia diagnosis linked to unnecessary medication use

by University of SydneyCredit: CC0 Public DomainA new international study led by University of Sydney has found that medication use increases in newly diagnosed dementia patients, particularly un

Updated on: May 11,2024

Dementia diagnosis linked to unnecessary medication use

by University of SydneyCredit: CC0 Public DomainA new international study led by University of Sydney has found that medication use increases in newly diagnosed dementia patients, particularly un

Updated on:May 11,2024