Exercise-induced hormone irisin may reduce Alzheimer's disease plaque and tangle pathology in the brain

by Massachusetts General HospitalCredit: Rice UniversityResearchers who previously developed the first 3D human cell culture models of Alzheimer's disease (AD) that displays two major hallmar

Updated on: March 02,2024

Exercise-induced hormone irisin may reduce Alzheimer's disease plaque and tangle pathology in the brain

by Massachusetts General HospitalCredit: Rice UniversityResearchers who previously developed the first 3D human cell culture models of Alzheimer's disease (AD) that displays two major hallmar

Updated on:March 02,2024

Overwhelmed? Your astrocytes can help with that

by University of California, San FranciscoDissection of astrocyte Ca2+and behavioral state. (a) Representative 2P mean projection image from one ten-minute recording of in vivo astrocyte Gc

Updated on: February 05,2024

Overwhelmed? Your astrocytes can help with that

by University of California, San FranciscoDissection of astrocyte Ca2+and behavioral state. (a) Representative 2P mean projection image from one ten-minute recording of in vivo astrocyte Gc

Updated on:February 05,2024

Biogen reanalyzes studies, presses ahead on Alzheimer's drug

by Marilynn MarchioneIn this Aug. 14, 2018 file photo, Dr. William Burke goes over a PET brain scan at Banner Alzheimers Institute in Phoenix. The drug company Biogen Inc. says it will seek federal ap

Updated on: April 25,2024

Biogen reanalyzes studies, presses ahead on Alzheimer's drug

by Marilynn MarchioneIn this Aug. 14, 2018 file photo, Dr. William Burke goes over a PET brain scan at Banner Alzheimers Institute in Phoenix. The drug company Biogen Inc. says it will seek federal ap

Updated on:April 25,2024

Alzheimer's research—intracellular calcium store malfunction leads to brain hyperactivity

by Universitaet TübingenAmyloid proteins (plaques, blue) in the cerebral cortex of a mouse model of Alzheimer’s disease, surrounded by cortical immune cells (microglia, green). Activated microgli

Updated on: April 16,2024

Alzheimer's research—intracellular calcium store malfunction leads to brain hyperactivity

by Universitaet TübingenAmyloid proteins (plaques, blue) in the cerebral cortex of a mouse model of Alzheimer’s disease, surrounded by cortical immune cells (microglia, green). Activated microgli

Updated on:April 16,2024

Researchers determine how the hippocampus generates and sustains oscillations

byRIKENA fluorescence micrograph of a CA1 in a mouse’s hippocampus. RIKEN researchers silenced the pyramidal cells in this region. Credit: Adapted fromNature Communications(2024). DO

Updated on: August 08,2024

Researchers determine how the hippocampus generates and sustains oscillations

byRIKENA fluorescence micrograph of a CA1 in a mouse’s hippocampus. RIKEN researchers silenced the pyramidal cells in this region. Credit: Adapted fromNature Communications(2024). DO

Updated on:August 08,2024

Cognitive behavioral therapy found to ease how fibromyalgia pain is experienced by the brain

by Mass General BrighamCredit: CC0 Public DomainPatients living with fibromyalgia (FM)—a disease that predominantly affects women and is characterized by chronic pain, fatigue and brain fog—often

Updated on: March 02,2024

Cognitive behavioral therapy found to ease how fibromyalgia pain is experienced by the brain

by Mass General BrighamCredit: CC0 Public DomainPatients living with fibromyalgia (FM)—a disease that predominantly affects women and is characterized by chronic pain, fatigue and brain fog—often

Updated on:March 02,2024

Physicians debate best screening tools and practices for patients with potential dementia and cognitive impairment

by American College of PhysiciansCredit: Pixabay/CC0 Public DomainIn a new Annals 'Beyond the Guideline's feature, two experts review the available evidence about cognitive impairment to

Updated on: March 02,2024

Physicians debate best screening tools and practices for patients with potential dementia and cognitive impairment

by American College of PhysiciansCredit: Pixabay/CC0 Public DomainIn a new Annals 'Beyond the Guideline's feature, two experts review the available evidence about cognitive impairment to

Updated on:March 02,2024

Prediction of conversion to Alzheimer's disease with longitudinal measures and time-to-event data

by IOS PressPredicting the timing of Alzheimer's disease (AD) conversion for individuals with mild cognitive impairment (MCI) can be significantly improved by incorporating longitudinal chang

Updated on: March 07,2024

Prediction of conversion to Alzheimer's disease with longitudinal measures and time-to-event data

by IOS PressPredicting the timing of Alzheimer's disease (AD) conversion for individuals with mild cognitive impairment (MCI) can be significantly improved by incorporating longitudinal chang

Updated on:March 07,2024

Constant tinnitus is linked to altered brain activity

by Karolinska InstitutetGraphical absract. Credit: DOI: 10.1172/JCI155094There has to date been no reliable objective method of diagnosing tinnitus. Researchers from Karolinska Institutet now sho

Updated on: February 05,2024

Constant tinnitus is linked to altered brain activity

by Karolinska InstitutetGraphical absract. Credit: DOI: 10.1172/JCI155094There has to date been no reliable objective method of diagnosing tinnitus. Researchers from Karolinska Institutet now sho

Updated on:February 05,2024

Strategies to generate neuronal diversity

by Zhang Nannan,Chinese Academy of SciencesStrategies for generating neuronal diversity in cerebral cortex, retina and hypothalamus. Credit: IGDBThe complexity and function of the nervous system

Updated on: February 05,2024

Strategies to generate neuronal diversity

by Zhang Nannan,Chinese Academy of SciencesStrategies for generating neuronal diversity in cerebral cortex, retina and hypothalamus. Credit: IGDBThe complexity and function of the nervous system

Updated on:February 05,2024

Klotho-VS heterozygosity genotype linked to reduced alzheimer disease risk

(HealthDay)—Klotho-VS heterozygosity (KL-VSHET+status) is associated with a reduced risk for Alzheimer disease (AD) and β-amyloid (Aβ) burden in cognitively normal individuals aged older than 60

Updated on: March 30,2024

Klotho-VS heterozygosity genotype linked to reduced alzheimer disease risk

(HealthDay)—Klotho-VS heterozygosity (KL-VSHET+status) is associated with a reduced risk for Alzheimer disease (AD) and β-amyloid (Aβ) burden in cognitively normal individuals aged older than 60

Updated on:March 30,2024

Study investigates how effective multiple sclerosis medications are across racial and ethnic groups

byAmerican Academy of NeurologyCredit: Unsplash/CC0 Public DomainFor people with relapsing-remitting multiple sclerosis (MS), a new study has found that the drug ofatumumab is more effective tha

Updated on: July 31,2024

Study investigates how effective multiple sclerosis medications are across racial and ethnic groups

byAmerican Academy of NeurologyCredit: Unsplash/CC0 Public DomainFor people with relapsing-remitting multiple sclerosis (MS), a new study has found that the drug ofatumumab is more effective tha

Updated on:July 31,2024