A small T cell switch with a big impact

by Julius-Maximilians-Universität WürzburgCredit: CC0 Public DomainT cells play a key role in the human immune system. They are capable of distinguishing diseased or foreign tissue from the body&

Updated on: May 07,2024

A small T cell switch with a big impact

by Julius-Maximilians-Universität WürzburgCredit: CC0 Public DomainT cells play a key role in the human immune system. They are capable of distinguishing diseased or foreign tissue from the body&

Updated on:May 07,2024

ATP from sensory neuron-interneuron crosstalk is key to spreading inflammation in rheumatoid arthritis

by Hokkaido UniversityThe inflammation signal (IL-6 amplifier) in the affected joint (L) causes the secretion of ATP that transmits a signal through the spinal cord (DRG, L5), which in turn trigg

Updated on: June 06,2024

ATP from sensory neuron-interneuron crosstalk is key to spreading inflammation in rheumatoid arthritis

by Hokkaido UniversityThe inflammation signal (IL-6 amplifier) in the affected joint (L) causes the secretion of ATP that transmits a signal through the spinal cord (DRG, L5), which in turn trigg

Updated on:June 06,2024

Phosphorylation of Regnase-1 lets IL-17 run amok

by Osaka UniversityCredit: CC0 Public DomainWhen considering the role of the key immune molecule interleukin (IL)-17, the phrase "too much of a good thing" springs to mind. Because unli

Updated on: April 22,2024

Phosphorylation of Regnase-1 lets IL-17 run amok

by Osaka UniversityCredit: CC0 Public DomainWhen considering the role of the key immune molecule interleukin (IL)-17, the phrase "too much of a good thing" springs to mind. Because unli

Updated on:April 22,2024

Are low blood urate levels linked to a higher risk of premature death?

by WileyCredit: Unsplash/CC0 Public DomainNew research published inArthritis & Rheumatologysuggests that adults with low blood levels of urate, a breakdown product of metabolism,

Updated on: May 23,2024

Are low blood urate levels linked to a higher risk of premature death?

by WileyCredit: Unsplash/CC0 Public DomainNew research published inArthritis & Rheumatologysuggests that adults with low blood levels of urate, a breakdown product of metabolism,

Updated on:May 23,2024

Consensus statement issued on management of foot, ankle gout

(HealthDay)—The American College of Foot and Ankle Surgeons and the American Association of Nurse Practitioners-Orthopedics Specialty Practice Group have issued a new joint clinical consensus statemen

Updated on: April 20,2024

Consensus statement issued on management of foot, ankle gout

(HealthDay)—The American College of Foot and Ankle Surgeons and the American Association of Nurse Practitioners-Orthopedics Specialty Practice Group have issued a new joint clinical consensus statemen

Updated on:April 20,2024

World's first CAR-T cell therapy for a child with lupus

byFriedrich–Alexander University Erlangen–NurnbergThe medical team and their patient (left to right): Dr. Tobias Krickau, Dr. Nora Naumann-Bartsch, Patientin Uresa A., Prof. Dr. Markus Metzler,

Updated on: July 09,2024

World's first CAR-T cell therapy for a child with lupus

byFriedrich–Alexander University Erlangen–NurnbergThe medical team and their patient (left to right): Dr. Tobias Krickau, Dr. Nora Naumann-Bartsch, Patientin Uresa A., Prof. Dr. Markus Metzler,

Updated on:July 09,2024

Improving uniformity and quality of care for people undergoing intra-articular injection

by EULARCredit: CC0 Public DomainIntra-articular therapies (IAT) are frequently used to treat joint conditions such as gout, rheumatoid arthritis, or osteoarthritis. The procedure involves inserting a

Updated on: May 29,2024

Improving uniformity and quality of care for people undergoing intra-articular injection

by EULARCredit: CC0 Public DomainIntra-articular therapies (IAT) are frequently used to treat joint conditions such as gout, rheumatoid arthritis, or osteoarthritis. The procedure involves inserting a

Updated on:May 29,2024

Joint cell finding gives clues for improved treatment of rheumatoid arthritis

by University of GlasgowThe key to swift treatments to cure the pain of rheumatoid arthritis has been found in the joints of people with the condition who are in long-term remission.The study—pub

Updated on: May 13,2024

Joint cell finding gives clues for improved treatment of rheumatoid arthritis

by University of GlasgowThe key to swift treatments to cure the pain of rheumatoid arthritis has been found in the joints of people with the condition who are in long-term remission.The study—pub

Updated on:May 13,2024

40 percent of adolescents with food allergies experience frequent anaphylactic episodes

by Murdoch Childrens Research InstituteCredit: Murdoch Childrens Research InstituteA new study by researchers from the Murdoch Children's Research Institute (MCRI) has shown that 40 percent o

Updated on: April 02,2024

40 percent of adolescents with food allergies experience frequent anaphylactic episodes

by Murdoch Childrens Research InstituteCredit: Murdoch Childrens Research InstituteA new study by researchers from the Murdoch Children's Research Institute (MCRI) has shown that 40 percent o

Updated on:April 02,2024

Study dispels myth of exercise damage in the treatment of osteoarthritis of the knee

by Alison Ramsay,University of AberdeenCredit: CC0 Public DomainA study by scientists has discovered that therapeutic exercise does not harm articular cartilage of the knee in people with osteoa

Updated on: May 23,2024

Study dispels myth of exercise damage in the treatment of osteoarthritis of the knee

by Alison Ramsay,University of AberdeenCredit: CC0 Public DomainA study by scientists has discovered that therapeutic exercise does not harm articular cartilage of the knee in people with osteoa

Updated on:May 23,2024

STIM-mediated calcium influx regulates maintenance and selection of germinal center B cells: Study

by Osaka UniversityCredit:Journal of Experimental Medicine(2023). DOI: 10.1084/jem.20222178Germinal centers (GCs) are specialized microenvironments where antigen (Ag)-specific B cells

Updated on: April 22,2024

STIM-mediated calcium influx regulates maintenance and selection of germinal center B cells: Study

by Osaka UniversityCredit:Journal of Experimental Medicine(2023). DOI: 10.1084/jem.20222178Germinal centers (GCs) are specialized microenvironments where antigen (Ag)-specific B cells

Updated on:April 22,2024

Early and intensive treatment of rheumatoid arthritis reduces fatigue

by European League Against RheumatismCredit: CC0 Public DomainDisease-related, profound fatigue impairs the quality of life of many people with rheumatic and musculoskeletal diseases. A Belgian s

Updated on: June 26,2024

Early and intensive treatment of rheumatoid arthritis reduces fatigue

by European League Against RheumatismCredit: CC0 Public DomainDisease-related, profound fatigue impairs the quality of life of many people with rheumatic and musculoskeletal diseases. A Belgian s

Updated on:June 26,2024