Loosening chimeric antigen receptor's grip on T-regulatory cells improves function, researchers find

by Leslie Cantu,Medical University of South CarolinaCAR and endogenous TCR/CD28 activation result in phenotypically similar Tregs. Credit:Molecular Therapy—Methods & Clinical Developme

Updated on: January 11,2025

Loosening chimeric antigen receptor's grip on T-regulatory cells improves function, researchers find

by Leslie Cantu,Medical University of South CarolinaCAR and endogenous TCR/CD28 activation result in phenotypically similar Tregs. Credit:Molecular Therapy—Methods & Clinical Developme

Updated on:January 11,2025

Gut microbiome: Meet Roseburia intestinalis—the energy-producing bacterium that helps us fight against disease

by Conor Meehan,The ConversationCredit: Pixabay/CC0 Public DomainThe hundreds of species of microorganisms that comprise the microbiome all have different, unique roles.One of the important func

Updated on: March 27,2024

Gut microbiome: Meet Roseburia intestinalis—the energy-producing bacterium that helps us fight against disease

by Conor Meehan,The ConversationCredit: Pixabay/CC0 Public DomainThe hundreds of species of microorganisms that comprise the microbiome all have different, unique roles.One of the important func

Updated on:March 27,2024

Teens with chronic conditions face challenges and risks when they age out of pediatric rheumatology care

by Michelle Batthish and Stephanie Garner,The ConversationCredit: AI-generated imageLiving with severeinflammatory arthritisor any other serious condition of the joints, bones and mu

Updated on: May 19,2024

Teens with chronic conditions face challenges and risks when they age out of pediatric rheumatology care

by Michelle Batthish and Stephanie Garner,The ConversationCredit: AI-generated imageLiving with severeinflammatory arthritisor any other serious condition of the joints, bones and mu

Updated on:May 19,2024

A small T cell switch with a big impact

by Julius-Maximilians-Universität WürzburgCredit: CC0 Public DomainT cells play a key role in the human immune system. They are capable of distinguishing diseased or foreign tissue from the body&

Updated on: May 07,2024

A small T cell switch with a big impact

by Julius-Maximilians-Universität WürzburgCredit: CC0 Public DomainT cells play a key role in the human immune system. They are capable of distinguishing diseased or foreign tissue from the body&

Updated on:May 07,2024

New analysis finds belimumab improves cutaneous lupus erythematosus in patients with or without SLE

by American College of RheumatologyForest plot of clinical response in CLE with or without SLE in belimumab users vs. non-users at week 52. Credit: Significant Improvement in Cutaneous Lupus Eryt

Updated on: May 29,2024

New analysis finds belimumab improves cutaneous lupus erythematosus in patients with or without SLE

by American College of RheumatologyForest plot of clinical response in CLE with or without SLE in belimumab users vs. non-users at week 52. Credit: Significant Improvement in Cutaneous Lupus Eryt

Updated on:May 29,2024

AI tool could dramatically decrease diagnostic times for psoriatic arthritis patients

by European Academy of Dermatology and VenereologyCredit: Unsplash/CC0 Public DomainResearchers in Israel have shown that a new machine-learning tool can speed up the diagnosis of psoriatic arthritis

Updated on: July 03,2024

AI tool could dramatically decrease diagnostic times for psoriatic arthritis patients

by European Academy of Dermatology and VenereologyCredit: Unsplash/CC0 Public DomainResearchers in Israel have shown that a new machine-learning tool can speed up the diagnosis of psoriatic arthritis

Updated on:July 03,2024

Fetal heart rate monitoring can help manage high-risk pregnancies

by American College of RheumatologyCredit: CC0 Public DomainNew research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, shows that heart rate m

Updated on: May 08,2024

Fetal heart rate monitoring can help manage high-risk pregnancies

by American College of RheumatologyCredit: CC0 Public DomainNew research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, shows that heart rate m

Updated on:May 08,2024

Scientists use blood test to track gene expression in the brain

by Kayt Sukel,Rice UniversityScan of mouse hippocampus and cortex, where the red signal derives from immunostaining for the synthetic marker developed by the Szablowski lab and the blue from the

Updated on: April 23,2024

Scientists use blood test to track gene expression in the brain

by Kayt Sukel,Rice UniversityScan of mouse hippocampus and cortex, where the red signal derives from immunostaining for the synthetic marker developed by the Szablowski lab and the blue from the

Updated on:April 23,2024

COVID-19 virus rapidly evolves to higher infectivity during in vitro growth, which may be a step toward lower virulence

by Jeff Hansen,University of Alabama at BirminghamCredit: Pixabay/CC0 Public DomainViruses accumulate mutations as they replicate in infected cells. Repeated replication can lead to viral strain

Updated on: April 10,2024

COVID-19 virus rapidly evolves to higher infectivity during in vitro growth, which may be a step toward lower virulence

by Jeff Hansen,University of Alabama at BirminghamCredit: Pixabay/CC0 Public DomainViruses accumulate mutations as they replicate in infected cells. Repeated replication can lead to viral strain

Updated on:April 10,2024

Discovery unveils immune system's guardian: Ikaros

byMonash UniversityCredit: Pixabay/CC0 Public DomainIn a scientific breakthrough that aids our understanding of the internal wiring of immune cells, researchers at Monash University in Australia

Updated on: January 26,2024

Discovery unveils immune system's guardian: Ikaros

byMonash UniversityCredit: Pixabay/CC0 Public DomainIn a scientific breakthrough that aids our understanding of the internal wiring of immune cells, researchers at Monash University in Australia

Updated on:January 26,2024

Early and intensive treatment of rheumatoid arthritis reduces fatigue

by European League Against RheumatismCredit: CC0 Public DomainDisease-related, profound fatigue impairs the quality of life of many people with rheumatic and musculoskeletal diseases. A Belgian s

Updated on: June 26,2024

Early and intensive treatment of rheumatoid arthritis reduces fatigue

by European League Against RheumatismCredit: CC0 Public DomainDisease-related, profound fatigue impairs the quality of life of many people with rheumatic and musculoskeletal diseases. A Belgian s

Updated on:June 26,2024

Study finds opioids double risk of venous thromboembolism in rheumatoid arthritis patients

by American College of RheumatologyRisk of outcomes (HR, 95% CI) with opioid initiation compared to NSAID initiation after adjustment for propensity score weights and imbalanced covariables (CVD

Updated on: May 13,2024

Study finds opioids double risk of venous thromboembolism in rheumatoid arthritis patients

by American College of RheumatologyRisk of outcomes (HR, 95% CI) with opioid initiation compared to NSAID initiation after adjustment for propensity score weights and imbalanced covariables (CVD

Updated on:May 13,2024