99

Breakthroughs
Sub Categories on Breakthroughs
Latest Articles
Team develops a single-nucleus resolution atlas of white adipose tissue in different depots

Team develops a single-nucleus resolution atlas of white adipose tissue in different depots

FEBRUARY 5, 2024by Higher Education PressWorkflow to perform snRNA-seq of different WAT depots. The nuclei were derived from subcutaneous (S), epididymal (E), mesenteric (M), peri-nephritic (N), and p

Team develops a single-nucleus resolution atlas of white adipose tissue in different depots

FEBRUARY 5, 2024by Higher Education PressWorkflow to perform snRNA-seq of different WAT depots. The nuclei were derived from subcutaneous (S), epididymal (E), mesenteric (M), peri-nephritic (N), and p
Extra fingers and hearts: Pinpointing changes to our genetic instructions that disrupt development

Extra fingers and hearts: Pinpointing changes to our genetic instructions that disrupt development

by Mario Aguilera,University of California - San DiegoChanging the instructions for development: Single-letter changes to genomes led to the formation of an extra digit (right). Credit: Fabian L

Extra fingers and hearts: Pinpointing changes to our genetic instructions that disrupt development

by Mario Aguilera,University of California - San DiegoChanging the instructions for development: Single-letter changes to genomes led to the formation of an extra digit (right). Credit: Fabian L
Blended antioxidant supplement found to improve cognition and memory in aged mice

Blended antioxidant supplement found to improve cognition and memory in aged mice

by Shibaura Institute of TechnologyAdministration of Twendee X (TwX) improves spatial learning ability in aged mice. The spatial cognition test's average goal time (escape latency) is shown i

Blended antioxidant supplement found to improve cognition and memory in aged mice

by Shibaura Institute of TechnologyAdministration of Twendee X (TwX) improves spatial learning ability in aged mice. The spatial cognition test's average goal time (escape latency) is shown i
New study shows a role for cholesterol in pain perception

New study shows a role for cholesterol in pain perception

FEBRUARY 27, 2024byUniversity of FloridaA cell membrane is illustrated to show the surface in red. Blue objects are proteins, including ion channels, which can send electrical impulses into cell

New study shows a role for cholesterol in pain perception

FEBRUARY 27, 2024byUniversity of FloridaA cell membrane is illustrated to show the surface in red. Blue objects are proteins, including ion channels, which can send electrical impulses into cell
Disruption of mitochondrial unfolded protein response yields shortening of telomeres in mouse oocytes, somatic cells

Disruption of mitochondrial unfolded protein response yields shortening of telomeres in mouse oocytes, somatic cells

FEBRUARY 21, 2024by Impact Journals LLCRepresentative confocal images of TRF1 expression and TRF/H2AX co-localization in cumulus oophorus isolated from 6-month-old wild-type and Clpp−/−mice. Cre

Disruption of mitochondrial unfolded protein response yields shortening of telomeres in mouse oocytes, somatic cells

FEBRUARY 21, 2024by Impact Journals LLCRepresentative confocal images of TRF1 expression and TRF/H2AX co-localization in cumulus oophorus isolated from 6-month-old wild-type and Clpp−/−mice. Cre
Analysis of research grants pipeline illustrates systematic disadvantages

Analysis of research grants pipeline illustrates systematic disadvantages

FEBRUARY 21, 2024by Roger Anderson,Northwestern UniversityRate of K99 and R00 awards and conversion by year. Credit:eLife(2024). DOI: 10.7554/eLife.88984.4Of the more than 3,000 extr

Analysis of research grants pipeline illustrates systematic disadvantages

FEBRUARY 21, 2024by Roger Anderson,Northwestern UniversityRate of K99 and R00 awards and conversion by year. Credit:eLife(2024). DOI: 10.7554/eLife.88984.4Of the more than 3,000 extr
Scientists explore the coupling between health span and lifespan in Caenorhabditis

Scientists explore the coupling between health span and lifespan in Caenorhabditis

by Impact Journals LLCPotential effects of compounds on lifespan and health. Credit: 2024 Banse et al.A new research paper waspublishedinAgingtitled, "The coupling between

Scientists explore the coupling between health span and lifespan in Caenorhabditis

by Impact Journals LLCPotential effects of compounds on lifespan and health. Credit: 2024 Banse et al.A new research paper waspublishedinAgingtitled, "The coupling between
Team assesses biological functions, diseases and therapeutic targets of heat shock protein 90

Team assesses biological functions, diseases and therapeutic targets of heat shock protein 90

by Sichuan International Medical Exchange and Promotion AssociationHSP90 chaperone undergoes dynamic cycling process: HSP90 transits between open and closed states to promote maturation of polypeptide

Team assesses biological functions, diseases and therapeutic targets of heat shock protein 90

by Sichuan International Medical Exchange and Promotion AssociationHSP90 chaperone undergoes dynamic cycling process: HSP90 transits between open and closed states to promote maturation of polypeptide
Combining genomics and metabolism identifies long-sought mitochondrial choline transporter

Combining genomics and metabolism identifies long-sought mitochondrial choline transporter

byVanderbilt University Medical CenterCredit: Unsplash/CC0 Public DomainA multidisciplinary research team has developed a discovery platform to probe the function of genes involved in metabolism

Combining genomics and metabolism identifies long-sought mitochondrial choline transporter

byVanderbilt University Medical CenterCredit: Unsplash/CC0 Public DomainA multidisciplinary research team has developed a discovery platform to probe the function of genes involved in metabolism
Researchers find genetic variant coding for tubulin protein that may be partially responsible for left-handedness

Researchers find genetic variant coding for tubulin protein that may be partially responsible for left-handedness

by Bob Yirka , Medical XpressExome-wide, gene-based association testing in 38,043 left-handed and 313,271 right-handed individuals, based on rare protein-altering variants. Top: the strict variant set

Researchers find genetic variant coding for tubulin protein that may be partially responsible for left-handedness

by Bob Yirka , Medical XpressExome-wide, gene-based association testing in 38,043 left-handed and 313,271 right-handed individuals, based on rare protein-altering variants. Top: the strict variant set
Study finds online doctors do not prescribe more antibiotics than other providers

Study finds online doctors do not prescribe more antibiotics than other providers

by Ola Nilsson,Umea UniversityCredit: Pixabay/CC0 Public DomainDoctors in virtual online health care contacts are no more likely to prescribe antibiotics for infections than doctors in regular h

Study finds online doctors do not prescribe more antibiotics than other providers

by Ola Nilsson,Umea UniversityCredit: Pixabay/CC0 Public DomainDoctors in virtual online health care contacts are no more likely to prescribe antibiotics for infections than doctors in regular h