Insights into epigenetics: The humanized FKBP5 mouse as a model organism

by Anke Schlee,Max Planck SocietySummary of study design and cohorts. Credit:Molecular Psychiatry(2024). DOI: 10.1038/s41380-024-02430-xThe candidate gene FKBP5 is involved in the de

Updated on: March 14,2024

Insights into epigenetics: The humanized FKBP5 mouse as a model organism

by Anke Schlee,Max Planck SocietySummary of study design and cohorts. Credit:Molecular Psychiatry(2024). DOI: 10.1038/s41380-024-02430-xThe candidate gene FKBP5 is involved in the de

Updated on:March 14,2024

Research harnesses machine learning and imaging to give insight into stem cell behavior

by Greta Harrison,University of Southern CaliforniaSingle hematopoietic stem cells dividing metabolically (m) symmetrically and asymmetrically, measured by the research team’s imaging technique.

Updated on: July 05,2024

Research harnesses machine learning and imaging to give insight into stem cell behavior

by Greta Harrison,University of Southern CaliforniaSingle hematopoietic stem cells dividing metabolically (m) symmetrically and asymmetrically, measured by the research team’s imaging technique.

Updated on:July 05,2024

CD32 as a Specific Marker for Hematopoietic Endothelial Cells in Human Embryonic Development: Insights and Implications for In Vitro Hematopoietic Cell Generation

Updated on: October 24,2024

CD32 as a Specific Marker for Hematopoietic Endothelial Cells in Human Embryonic Development: Insights and Implications for In Vitro Hematopoietic Cell Generation

Updated on:October 24,2024

Metabolic remodeling in endothelial cells and macrophages contributes to plaque instability and vulnerability

Updated on: October 02,2024

Metabolic remodeling in endothelial cells and macrophages contributes to plaque instability and vulnerability

Updated on:October 02,2024

Chemical and computational advances enable 2D proteomics measurements of spatial signals

FEBRUARY 5, 2024byPacific Northwest National LaboratoryMicroPOTS is a chip-based approach developed by Pacific Northwest National Laboratory that allows sample processing in a microliter droplet

Updated on: March 15,2024

Chemical and computational advances enable 2D proteomics measurements of spatial signals

FEBRUARY 5, 2024byPacific Northwest National LaboratoryMicroPOTS is a chip-based approach developed by Pacific Northwest National Laboratory that allows sample processing in a microliter droplet

Updated on:March 15,2024

Discovery enables effective use of gene therapy for muscular dystrophies and other large-gene diseases

byUniversity of Rochester Medical CenterCredit: Pixabay/CC0 Public DomainGene therapy can effectively treat various diseases, but for some debilitating conditions like muscular dystrophies there

Updated on: November 22,2024

Discovery enables effective use of gene therapy for muscular dystrophies and other large-gene diseases

byUniversity of Rochester Medical CenterCredit: Pixabay/CC0 Public DomainGene therapy can effectively treat various diseases, but for some debilitating conditions like muscular dystrophies there

Updated on:November 22,2024

Zebrafish's eye muscles give hope for people with muscular dystrophy diseases

by Claes Björnberg,Umea UniversityAxon and NMJ integrity is partially rescued by overexpression of fhl2b in trunk muscle of 5 dpf dmd-/-zebrafish larvae. Credit: https://umu.diva-portal.or

Updated on: March 14,2024

Zebrafish's eye muscles give hope for people with muscular dystrophy diseases

by Claes Björnberg,Umea UniversityAxon and NMJ integrity is partially rescued by overexpression of fhl2b in trunk muscle of 5 dpf dmd-/-zebrafish larvae. Credit: https://umu.diva-portal.or

Updated on:March 14,2024

Urine test halves painful procedures in bladder cancer follow up, new trial shows

by European Association of UrologyCredit: Unsplash/CC0 Public DomainA simple urine test can more than halve the number of cystoscopies necessary to follow up high-risk bladder cancer patients, ne

Updated on: April 06,2024

Urine test halves painful procedures in bladder cancer follow up, new trial shows

by European Association of UrologyCredit: Unsplash/CC0 Public DomainA simple urine test can more than halve the number of cystoscopies necessary to follow up high-risk bladder cancer patients, ne

Updated on:April 06,2024

One in five US cancer patients join in medical research

by Dennis ThompsonMore patients these days are taking part in cancer research, a new study finds.At least one in five people with cancer (22%) participate in some form of clinical research, when all t

Updated on: April 06,2024

One in five US cancer patients join in medical research

by Dennis ThompsonMore patients these days are taking part in cancer research, a new study finds.At least one in five people with cancer (22%) participate in some form of clinical research, when all t

Updated on:April 06,2024

Study identifies epigenetic 'switches' that regulate the developmental trajectories of single cells

by Ingrid Fadelli , Medical XpressAnalysis of the developmental cell atlas. a, Workflow to obtain single-cell RNA (scRNA) expression and CUT&Tag data for three histone modifications (H3K27me3, H3K

Updated on: July 17,2024

Study identifies epigenetic 'switches' that regulate the developmental trajectories of single cells

by Ingrid Fadelli , Medical XpressAnalysis of the developmental cell atlas. a, Workflow to obtain single-cell RNA (scRNA) expression and CUT&Tag data for three histone modifications (H3K27me3, H3K

Updated on:July 17,2024

New technique for revealing genetic repeats yields surprising insights into Huntington's disease

byRockefeller UniversityCredit:Neuron(2024). DOI: 10.1016/j.neuron.2023.12.009Neurodegenerative diseases are among the most complex human ailments, and their exact causes and mechani

Updated on: March 13,2024

New technique for revealing genetic repeats yields surprising insights into Huntington's disease

byRockefeller UniversityCredit:Neuron(2024). DOI: 10.1016/j.neuron.2023.12.009Neurodegenerative diseases are among the most complex human ailments, and their exact causes and mechani

Updated on:March 13,2024

Research provides further evidence that epigenetic changes can cause type 2 diabetes

byLund UniversityStudy design. EPIC array DNA methylation in islets of 25 T2D cases and 75 controls. RNA-seq data were available for 25 T2D cases and 72 controls. Islet DNA methylation was assoc

Updated on: March 13,2024

Research provides further evidence that epigenetic changes can cause type 2 diabetes

byLund UniversityStudy design. EPIC array DNA methylation in islets of 25 T2D cases and 75 controls. RNA-seq data were available for 25 T2D cases and 72 controls. Islet DNA methylation was assoc

Updated on:March 13,2024