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Pelage Pharmaceuticals Advances Hair Loss Treatment with Phase 2 Study and $14M Funding

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Pelage Pharmaceuticals has commenced dosing the first patients in its Phase 2a clinical trial for PP405, a novel topical treatment designed to reactivate dormant hair follicle stem cells.
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Blood Types: What Letters, Positive, and Negative Signs Mean

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World medicine November 21,2023
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Antibodies From Cured AML Patients Kill Leukemia Cells

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June 12, 2016Jason M. BroderickPatients with acute myeloid leukemia who are cured after allogeneic hematopoietic stem cell transplantation produce antibodies that destroy leukemia cells.Mette D. Hazen
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Antibodies From Cured AML Patients Kill Leukemia Cells

Antibodies From Cured AML Patients Kill Leukemia Cells

June 12, 2016Jason M. BroderickPatients with acute myeloid leukemia who are cured after allogeneic hematopoietic stem cell transplantation produce antibodies that destroy leukemia cells.Mette D. Hazen
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Hematopoietic Stem Cell Transplant: A Viable Option for Older Patients With AML

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March 27, 2020Mark B. Juckett, MDThe challenge in caring for older patients is developing a risk-adapted strategy that best meets the patients’ identified goals and accounts for a realistic assessment
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Hematopoietic Stem Cell Transplant: A Viable Option for Older Patients With AML

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Carving Out New Combination Therapies in Stem Cell Disorders

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Carving Out New Combination Therapies in Stem Cell Disorders

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July 13, 2020Caroline SeymourDespite the influx of novel agents that have received regulatory approval in recent years in stem cell disorders, there is still room for improvement.William B. Donnellan,
World medicine November 21,2023
Prophylactic Letermovir Limits CMV Infections Post-Transplantation

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February 26, 2017Silas InmanProphylactic treatment with letermovir lowered the rates of cytomegalovirus infection and all-cause mortality compared with placebo for CMV-seropositive patients following
World medicine November 21,2023
Prophylactic Letermovir Limits CMV Infections Post-Transplantation

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February 26, 2017Silas InmanProphylactic treatment with letermovir lowered the rates of cytomegalovirus infection and all-cause mortality compared with placebo for CMV-seropositive patients following
World medicine November 21,2023
Ixazomib Maintenance Shows Robust Activity in Multiple Myeloma

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June 24, 2017Virginia Powers, PhDPatients with newly-diagnosed multiple myeloma who did not elect to undergo stem cell transplant but remained on single agent ixazomib maintenance fared as well as tho
World medicine November 21,2023
Ixazomib Maintenance Shows Robust Activity in Multiple Myeloma

Ixazomib Maintenance Shows Robust Activity in Multiple Myeloma

June 24, 2017Virginia Powers, PhDPatients with newly-diagnosed multiple myeloma who did not elect to undergo stem cell transplant but remained on single agent ixazomib maintenance fared as well as tho
World medicine November 21,2023
Protein-triggered motor neuron loss in amyotrophic lateral sclerosis

Protein-triggered motor neuron loss in amyotrophic lateral sclerosis

The intricate control of our bodily movements relies on a network of neural pathways connecting the brain and spinal cord. Key among these pathways is the transmission of commands from neurons in the
World medicine November 21,2023
Protein-triggered motor neuron loss in amyotrophic lateral sclerosis

Protein-triggered motor neuron loss in amyotrophic lateral sclerosis

The intricate control of our bodily movements relies on a network of neural pathways connecting the brain and spinal cord. Key among these pathways is the transmission of commands from neurons in the
World medicine November 21,2023
First-Line Dose-Dense Induction and High-Dose Chemotherapy/Autologous Stem Cell Transplant Benefits Patients With Rare Lymphomas

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October 8, 2012Jill SteinDose-dense induction with high-dose chemotherapy/autologous stem-cell transplantation is reasonable for use as first-line treatment of transplantation-eligible patients with s
World medicine November 21,2023
First-Line Dose-Dense Induction and High-Dose Chemotherapy/Autologous Stem Cell Transplant Benefits Patients With Rare Lymphomas

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October 8, 2012Jill SteinDose-dense induction with high-dose chemotherapy/autologous stem-cell transplantation is reasonable for use as first-line treatment of transplantation-eligible patients with s
World medicine November 21,2023
Researchers Highlight Ibrutinib Efficacy in Posttransplant, High-Risk CLL

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February 18, 2015Jason M. BroderickIbrutinib (Imbruvica) showed promising activity in heavily pretreated, relapsed/refractory chronic lymphocytic leukemia after allogeneic stem cell transplantation, a
World medicine November 21,2023
Researchers Highlight Ibrutinib Efficacy in Posttransplant, High-Risk CLL

Researchers Highlight Ibrutinib Efficacy in Posttransplant, High-Risk CLL

February 18, 2015Jason M. BroderickIbrutinib (Imbruvica) showed promising activity in heavily pretreated, relapsed/refractory chronic lymphocytic leukemia after allogeneic stem cell transplantation, a
World medicine November 21,2023
Study Results May Change Treatment Standard for Patients Receiving Transplants From Unrelated Donors

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December 21, 2012Ben LeachPatients receiving transplants from unrelated donors to treat various hematologic malignancies may benefit more from receiving adult stem cells harvested from bone marrow rat
World medicine November 21,2023
Study Results May Change Treatment Standard for Patients Receiving Transplants From Unrelated Donors

Study Results May Change Treatment Standard for Patients Receiving Transplants From Unrelated Donors

December 21, 2012Ben LeachPatients receiving transplants from unrelated donors to treat various hematologic malignancies may benefit more from receiving adult stem cells harvested from bone marrow rat
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