CRISPR-Cas9 datasets analysis leads to largest genetic screen resource for cancer research

byWellcome Trust Sanger InstituteCredit: CC0 Public DomainA comprehensive map of genes necessary for cancer survival is one step closer, following the validation of the two largest CRISPR-Cas9 g

Oncology December 22,2023

CRISPR-Cas9 datasets analysis leads to largest genetic screen resource for cancer research

byWellcome Trust Sanger InstituteCredit: CC0 Public DomainA comprehensive map of genes necessary for cancer survival is one step closer, following the validation of the two largest CRISPR-Cas9 g

Oncology December 22,2023

Breast cancer cells swallow a 'free lunch' of dietary fat particles from the bloodstream

byDartmouth-Hitchcock Medical CenterLipoprotein Lipase facilitates binding of very low density lipoprotein particles (red) to breast cancer cells (blue cell nuclei). Credit: William Kinlaw, III,

Oncology December 22,2023

Breast cancer cells swallow a 'free lunch' of dietary fat particles from the bloodstream

byDartmouth-Hitchcock Medical CenterLipoprotein Lipase facilitates binding of very low density lipoprotein particles (red) to breast cancer cells (blue cell nuclei). Credit: William Kinlaw, III,

Oncology December 22,2023

Structural analysis reveals an unexpected mechanism for a cancer drug

by Tim Stephens,University of California - Santa CruzThe breast cancer drug palbociclib (grey) interacts with its target protein CDK4 (green) in this structural model. Binding of the activator p

Oncology December 22,2023

Structural analysis reveals an unexpected mechanism for a cancer drug

by Tim Stephens,University of California - Santa CruzThe breast cancer drug palbociclib (grey) interacts with its target protein CDK4 (green) in this structural model. Binding of the activator p

Oncology December 22,2023

Diagnostic test helps find bloodstream infections before they appear

bySt. Jude Children's Research HospitalCredit: CC0 Public DomainA test called microbial cell-free DNA identified potentially lethal bloodstream infections in children with relapsed leukemia

Public Health & Prevention December 22,2023

Diagnostic test helps find bloodstream infections before they appear

bySt. Jude Children's Research HospitalCredit: CC0 Public DomainA test called microbial cell-free DNA identified potentially lethal bloodstream infections in children with relapsed leukemia

Public Health & Prevention December 22,2023

Lack of self-exams hampers early melanoma identification

(HealthDay)—The biggest obstacle to early detection and treatment of melanoma among residents of rural, frontier communities is a chronic lack of skin self-examination (SSE), according to a study rece

Oncology December 22,2023

Lack of self-exams hampers early melanoma identification

(HealthDay)—The biggest obstacle to early detection and treatment of melanoma among residents of rural, frontier communities is a chronic lack of skin self-examination (SSE), according to a study rece

Oncology December 22,2023

Patient-reported outcomes predict aromatase inhibitor adherence

by SWOGCredit: CC0 Public DomainIf you want to predict which breast cancer patients will most likely stop taking aromatase inhibitors, check out their own responses to the health questions patients co

Oncology December 22,2023

Patient-reported outcomes predict aromatase inhibitor adherence

by SWOGCredit: CC0 Public DomainIf you want to predict which breast cancer patients will most likely stop taking aromatase inhibitors, check out their own responses to the health questions patients co

Oncology December 22,2023

Metabolic adaptation ensures survival of colon cancer cells

byGerman Cancer Research CenterCredit: CC0 Public DomainColon cancer cells deficient in p53, one of the most important control proteins in cell growth, activate a particular metabolic pathway to

Oncology December 22,2023

Metabolic adaptation ensures survival of colon cancer cells

byGerman Cancer Research CenterCredit: CC0 Public DomainColon cancer cells deficient in p53, one of the most important control proteins in cell growth, activate a particular metabolic pathway to

Oncology December 22,2023

Newly developed mathematical model could be used to predict cancer drug side effects in individuals

byKobe UniversityA bar graph to show drug metabolism predictions for the anti-cancer agent Irinotecan (the gray bars are the predictions and the black bars are the actual results). The shorter t

Oncology December 22,2023

Newly developed mathematical model could be used to predict cancer drug side effects in individuals

byKobe UniversityA bar graph to show drug metabolism predictions for the anti-cancer agent Irinotecan (the gray bars are the predictions and the black bars are the actual results). The shorter t

Oncology December 22,2023

Chemotherapy drug temozolomide analog shows promise in treating glioma

by Bob Yirka , Medical XpressCredit: Unsplash/CC0 Public DomainA team of researchers from Yale University and Yale School of Medicine has developed a temozolomide analog for use as a chemotherapy drug

Oncology December 22,2023

Chemotherapy drug temozolomide analog shows promise in treating glioma

by Bob Yirka , Medical XpressCredit: Unsplash/CC0 Public DomainA team of researchers from Yale University and Yale School of Medicine has developed a temozolomide analog for use as a chemotherapy drug

Oncology December 22,2023

Fibroblasts involved in healing spur tumor growth in cancer

byTel Aviv UniversityCredit: Tel Aviv UniversityThe connective tissue cells known as fibroblasts are vitally important for our recovery from injury. Sensing tissue damage, they gravitate to the

Oncology December 22,2023

Fibroblasts involved in healing spur tumor growth in cancer

byTel Aviv UniversityCredit: Tel Aviv UniversityThe connective tissue cells known as fibroblasts are vitally important for our recovery from injury. Sensing tissue damage, they gravitate to the

Oncology December 22,2023