Genetic tests create treatment opportunities and confusion for breast cancer patients

by Michelle AndrewsCredit: Pixabay/CC0 Public DomainThe past decade has witnessed a rapid expansion of genetic tests, including new instruments to inform patients who have been diagnosed with breast c

Oncology December 25,2023

Genetic tests create treatment opportunities and confusion for breast cancer patients

by Michelle AndrewsCredit: Pixabay/CC0 Public DomainThe past decade has witnessed a rapid expansion of genetic tests, including new instruments to inform patients who have been diagnosed with breast c

Oncology December 25,2023

Gene and cell therapies to combat pancreatic cancer

byMary Ann Liebert, IncGTMP clinical trials for pancreatic cancer depending on phase and trial status. Source: Clinical trial.gov. GTMPs, gene therapy medicinal products. Credit:Human Gene

Oncology December 25,2023

Gene and cell therapies to combat pancreatic cancer

byMary Ann Liebert, IncGTMP clinical trials for pancreatic cancer depending on phase and trial status. Source: Clinical trial.gov. GTMPs, gene therapy medicinal products. Credit:Human Gene

Oncology December 25,2023

Genetic discovery could improve treatment of colorectal cancer

by Rémi Carlier,Ecole Polytechnique Federale de LausannePOU5F1B differs from OCT4. a Representative immunofluorescence–confocal microscopy of POU5F1B-HA overexpressing SW480 cells, with DAPI in

Oncology December 25,2023

Genetic discovery could improve treatment of colorectal cancer

by Rémi Carlier,Ecole Polytechnique Federale de LausannePOU5F1B differs from OCT4. a Representative immunofluorescence–confocal microscopy of POU5F1B-HA overexpressing SW480 cells, with DAPI in

Oncology December 25,2023

Gene loss enhances metastasis and cancer progression

by Melissa Rohman,Northwestern UniversityAn in vivo genome-wide CRISPR-Cas9 KO screen identifying CTC-promoting genetic factors. (A) Experimental design of the genome-wide CRISPR-Cas9 KO screen

Oncology December 25,2023

Gene loss enhances metastasis and cancer progression

by Melissa Rohman,Northwestern UniversityAn in vivo genome-wide CRISPR-Cas9 KO screen identifying CTC-promoting genetic factors. (A) Experimental design of the genome-wide CRISPR-Cas9 KO screen

Oncology December 25,2023

Gene signature points to prognosis in kidney cancer

byKarolinska InstitutetSingle-cell landscape of the ecosystem in primary ccRCC and adjacent normal tissue.aExperimental design created with Biorender.com and Adobe Illustrator.

Oncology December 25,2023

Gene signature points to prognosis in kidney cancer

byKarolinska InstitutetSingle-cell landscape of the ecosystem in primary ccRCC and adjacent normal tissue.aExperimental design created with Biorender.com and Adobe Illustrator.

Oncology December 25,2023

Basic research opens up new therapeutic opportunities for fighting leukemia

byUniversity of Veterinary Medicine—ViennaGenome-wide CRISPR/Cas9-based loss-of-function screen identifies genetic dependencies of STAT3Y640F-driven cells a) Schematic illustration of a competit

Oncology December 25,2023

Basic research opens up new therapeutic opportunities for fighting leukemia

byUniversity of Veterinary Medicine—ViennaGenome-wide CRISPR/Cas9-based loss-of-function screen identifies genetic dependencies of STAT3Y640F-driven cells a) Schematic illustration of a competit

Oncology December 25,2023

Reprogramming tissue mechanically to promote wound healing

by Jan Berndorff,Paul Scherrer InstituteImplanted PR cells show rejuvenation properties in an aged skin model. Credit:Aging Cell(2023). DOI: 10.1111/acel.14032Researchers at PSI and

Breakthroughs December 25,2023

Reprogramming tissue mechanically to promote wound healing

by Jan Berndorff,Paul Scherrer InstituteImplanted PR cells show rejuvenation properties in an aged skin model. Credit:Aging Cell(2023). DOI: 10.1111/acel.14032Researchers at PSI and

Breakthroughs December 25,2023

The power of machine learning in prostate cancer imaging

by Lisette Hilton,University of Miami(From left) Isaac R. L. Xu; Derek J. Van Booven; and Himanshu Arora, Ph.D. Credit: University of MiamiResearchers at Sylvester Comprehensive Cancer Center an

Oncology December 25,2023

The power of machine learning in prostate cancer imaging

by Lisette Hilton,University of Miami(From left) Isaac R. L. Xu; Derek J. Van Booven; and Himanshu Arora, Ph.D. Credit: University of MiamiResearchers at Sylvester Comprehensive Cancer Center an

Oncology December 25,2023

Machine learning to identify cancer type-specific driver mutations for the development of new drug targets

by Pohang University of Science & Technology (POSTECH)Credit: POSTECHAccording to Statistics Korea, cancer is the top cause of death in 2021, accounting for 26% of deaths. Most cancer patients mis

Oncology December 25,2023

Machine learning to identify cancer type-specific driver mutations for the development of new drug targets

by Pohang University of Science & Technology (POSTECH)Credit: POSTECHAccording to Statistics Korea, cancer is the top cause of death in 2021, accounting for 26% of deaths. Most cancer patients mis

Oncology December 25,2023

Machine learning can help predict patient response to cancer immunotherapy

byJohns Hopkins University School of MedicineHLA-extended, MIL-supervised TCR repertoire model. We expand on previous work by modifying the TCR featurization block to incorporate the HLA backgro

Pediatrics December 25,2023

Machine learning can help predict patient response to cancer immunotherapy

byJohns Hopkins University School of MedicineHLA-extended, MIL-supervised TCR repertoire model. We expand on previous work by modifying the TCR featurization block to incorporate the HLA backgro

Pediatrics December 25,2023