West Virginia city once battered by opioid overdoses confronts 'fourth wave'

by Taylor Sisk, KFF Health NewsCredit: CC0 Public DomainFrom 2006 through 2014, more than 81 million painkiller pills were shipped to this city and surrounding rural Cabell County.The arrival of presc

Breakthroughs March 28,2024

West Virginia city once battered by opioid overdoses confronts 'fourth wave'

by Taylor Sisk, KFF Health NewsCredit: CC0 Public DomainFrom 2006 through 2014, more than 81 million painkiller pills were shipped to this city and surrounding rural Cabell County.The arrival of presc

Breakthroughs March 28,2024

New research identifies promising drug combination for multiple myeloma treatment

byRoyal College of Surgeons in IrelandCredit: Unsplash/CC0 Public DomainNew research from the Royal College of Surgeons in Ireland has found that venetoclax, a medication currently approved for

Breakthroughs March 28,2024

New research identifies promising drug combination for multiple myeloma treatment

byRoyal College of Surgeons in IrelandCredit: Unsplash/CC0 Public DomainNew research from the Royal College of Surgeons in Ireland has found that venetoclax, a medication currently approved for

Breakthroughs March 28,2024

Mifepristone access is coming before the US Supreme Court. How safe is this abortion pill?

by LAURA UNGAR and MATTHEW PERRONEBoxes of the drug mifepristone sit on a shelf at the West Alabama Women's Center in Tuscaloosa, Ala., on March 16, 2022. On Tuesday, March 26, 2024, the U.S. Supr

Breakthroughs March 28,2024

Mifepristone access is coming before the US Supreme Court. How safe is this abortion pill?

by LAURA UNGAR and MATTHEW PERRONEBoxes of the drug mifepristone sit on a shelf at the West Alabama Women's Center in Tuscaloosa, Ala., on March 16, 2022. On Tuesday, March 26, 2024, the U.S. Supr

Breakthroughs March 28,2024

Q&A: A digital twin that allows tailored medication

by Anna Björklund,Karolinska InstitutetOverview of the scDrugPrio workflow. Single-cell RNA-sequencing (scRNA-seq) data from either individuals or groups of patients are preprocessed by undergoi

Q & A March 28,2024

Q&A: A digital twin that allows tailored medication

by Anna Björklund,Karolinska InstitutetOverview of the scDrugPrio workflow. Single-cell RNA-sequencing (scRNA-seq) data from either individuals or groups of patients are preprocessed by undergoi

Q & A March 28,2024

There's only one syphilis medication for pregnant people and the supply is running out

by Alena Kuzub,Northeastern UniversityThe pharmaceutical company Pfizer is the sole manufacturer of penicillin G benzathine, the only medicine that safely treats syphilis in pregnant people. Cre

Breakthroughs March 28,2024

There's only one syphilis medication for pregnant people and the supply is running out

by Alena Kuzub,Northeastern UniversityThe pharmaceutical company Pfizer is the sole manufacturer of penicillin G benzathine, the only medicine that safely treats syphilis in pregnant people. Cre

Breakthroughs March 28,2024

Study finds antibiotics combat gut bacteria that contribute to the pathogenesis of COVID-19

byWileyChest images of completely vaccinated sick moderate patients with SARS-CoV-2. Panel A-D: Four cases of vaccinated patients with pneumonia, no previous antibiotic use before hospital admis

Breakthroughs March 28,2024

Study finds antibiotics combat gut bacteria that contribute to the pathogenesis of COVID-19

byWileyChest images of completely vaccinated sick moderate patients with SARS-CoV-2. Panel A-D: Four cases of vaccinated patients with pneumonia, no previous antibiotic use before hospital admis

Breakthroughs March 28,2024

Metformin during pregnancy impacts offspring brain development, finds study

by Deutsches Zentrum fuer Diabetesforschung DZDMaternal HFD intake during lactation leads to excessive maternal weight gain and hyperglycemia at weaning which is not affected by metformin treatment. C

Breakthroughs March 28,2024

Metformin during pregnancy impacts offspring brain development, finds study

by Deutsches Zentrum fuer Diabetesforschung DZDMaternal HFD intake during lactation leads to excessive maternal weight gain and hyperglycemia at weaning which is not affected by metformin treatment. C

Breakthroughs March 28,2024

New data show pembrolizumab improves breast cancer outcomes regardless of age or menopausal status

by European Organisation for Research and Treatment of CancerCredit: Unsplash/CC0 Public DomainNew data from the KEYNOTE-756 phase 3 clinical trial show that adding the immunotherapy drug pembrolizuma

Breakthroughs March 28,2024

New data show pembrolizumab improves breast cancer outcomes regardless of age or menopausal status

by European Organisation for Research and Treatment of CancerCredit: Unsplash/CC0 Public DomainNew data from the KEYNOTE-756 phase 3 clinical trial show that adding the immunotherapy drug pembrolizuma

Breakthroughs March 28,2024

Autophagy-tethering compounds may open new directions in targeted drug discovery

byScience China Press(A) Molecular glue ATTECs are targeting polyQ proteins in neurodegenerative disorders. (B) Bifunctional ATTECs targeting oncoprotein BRD4. (C) Bifunctional ATTECs targeting

Breakthroughs March 28,2024

Autophagy-tethering compounds may open new directions in targeted drug discovery

byScience China Press(A) Molecular glue ATTECs are targeting polyQ proteins in neurodegenerative disorders. (B) Bifunctional ATTECs targeting oncoprotein BRD4. (C) Bifunctional ATTECs targeting

Breakthroughs March 28,2024

Study eases concern at antipsychotics use in pregnancy

byUniversity of New South WalesCrude and propensity score-weighted cumulative incidence (with 95% confidence intervals) for composite neurodevelopmental outcome from age 3–19 years in children o

Breakthroughs March 28,2024

Study eases concern at antipsychotics use in pregnancy

byUniversity of New South WalesCrude and propensity score-weighted cumulative incidence (with 95% confidence intervals) for composite neurodevelopmental outcome from age 3–19 years in children o

Breakthroughs March 28,2024