A new vision for AAV-delivered gene therapies

by Benjamin Boettner,Harvard UniversityAAVs with TLR9-inhibitory sequences incorporated into their genomes allowed significantly higher expression of a linked fluorescent reporter gene in the mo

Breakthroughs April 02,2024

A new vision for AAV-delivered gene therapies

by Benjamin Boettner,Harvard UniversityAAVs with TLR9-inhibitory sequences incorporated into their genomes allowed significantly higher expression of a linked fluorescent reporter gene in the mo

Breakthroughs April 02,2024

40 percent of adolescents with food allergies experience frequent anaphylactic episodes

by Murdoch Childrens Research InstituteCredit: Murdoch Childrens Research InstituteA new study by researchers from the Murdoch Children's Research Institute (MCRI) has shown that 40 percent o

Immunology & Rheumatology April 02,2024

40 percent of adolescents with food allergies experience frequent anaphylactic episodes

by Murdoch Childrens Research InstituteCredit: Murdoch Childrens Research InstituteA new study by researchers from the Murdoch Children's Research Institute (MCRI) has shown that 40 percent o

Immunology & Rheumatology April 02,2024

3-D printed pill samples gut microbiome to aid diagnosis and treatment

by Tufts UniversityBacteria in the gut are pulled into the helical channels by an osmotic 'pump' in the pill. Credit: Nano Lab, Tufts UniversityA research team led by Tufts University eng

Breakthroughs April 02,2024

3-D printed pill samples gut microbiome to aid diagnosis and treatment

by Tufts UniversityBacteria in the gut are pulled into the helical channels by an osmotic 'pump' in the pill. Credit: Nano Lab, Tufts UniversityA research team led by Tufts University eng

Breakthroughs April 02,2024

Discriminatory redlining practices in the 1930s associated with present-day rates of ED visits due to asthma

by LancetCredit: CC0 Public DomainCurrent rates of emergency department visits due to asthma are around 2.4 times higher in areas that were redlined—deprioritised for mortgage investment—in the 1

Immunology & Rheumatology April 02,2024

Discriminatory redlining practices in the 1930s associated with present-day rates of ED visits due to asthma

by LancetCredit: CC0 Public DomainCurrent rates of emergency department visits due to asthma are around 2.4 times higher in areas that were redlined—deprioritised for mortgage investment—in the 1

Immunology & Rheumatology April 02,2024

3-D-printed tumor model shows interaction with immune cells

by Wiebe Van Der Veen,University of TwenteThe size of the model, the red part is thetumor. Credit: University of TwenteAround a glioblastoma, a very aggressive brain tumor, cells of the hu

Oncology April 02,2024

3-D-printed tumor model shows interaction with immune cells

by Wiebe Van Der Veen,University of TwenteThe size of the model, the red part is thetumor. Credit: University of TwenteAround a glioblastoma, a very aggressive brain tumor, cells of the hu

Oncology April 02,2024

A T-cell stimulatory protein and interleukin-10 synergize to prevent gut inflammation

by Jeff Hansen,University of Alabama at BirminghamCredit: CC0 Public DomainResearchers have found an unexpected synergy between a T-cell stimulatory protein—the ICOS ligand—and interleukin-10, a

Gastroenterology April 01,2024

A T-cell stimulatory protein and interleukin-10 synergize to prevent gut inflammation

by Jeff Hansen,University of Alabama at BirminghamCredit: CC0 Public DomainResearchers have found an unexpected synergy between a T-cell stimulatory protein—the ICOS ligand—and interleukin-10, a

Gastroenterology April 01,2024

Could carbon monoxide foam help fight inflammation?

by Massachusetts Institute of TechnologyFoam gas-entrapping materials (GEMs). Credit: Massachusetts Institute of TechnologyCarbon monoxide is best known as a potentially deadly gas. However, in s

Immunology & Rheumatology April 01,2024

Could carbon monoxide foam help fight inflammation?

by Massachusetts Institute of TechnologyFoam gas-entrapping materials (GEMs). Credit: Massachusetts Institute of TechnologyCarbon monoxide is best known as a potentially deadly gas. However, in s

Immunology & Rheumatology April 01,2024

Rely on gut feeling? New research identifies how second brain in gut communicates

by Flinders UniversityCredit: Pixabay/CC0 Public DomainYou're faced with a big decision so your second brain provides what's normally referred to as "gut instinct," but how did

Neurology April 01,2024

Rely on gut feeling? New research identifies how second brain in gut communicates

by Flinders UniversityCredit: Pixabay/CC0 Public DomainYou're faced with a big decision so your second brain provides what's normally referred to as "gut instinct," but how did

Neurology April 01,2024

A disease trigger for pancreatitis has been identified

by Technical University MunichA Calcium channel is involved in the development of pancreatitis Credit: Prof. Dr. Heiko WittPatients suffering from chronic pancreatitis experience an either recurr

Gastroenterology April 01,2024

A disease trigger for pancreatitis has been identified

by Technical University MunichA Calcium channel is involved in the development of pancreatitis Credit: Prof. Dr. Heiko WittPatients suffering from chronic pancreatitis experience an either recurr

Gastroenterology April 01,2024

A simple compound to control complex gut microbes

by RIKENAcetate increased IgA production (yellow). IgA bound to potentially harmful bacteria (green), and prevented them from invading the mucus layer (red). Credit: RIKENResearchers at the RIKEN

Gastroenterology April 01,2024

A simple compound to control complex gut microbes

by RIKENAcetate increased IgA production (yellow). IgA bound to potentially harmful bacteria (green), and prevented them from invading the mucus layer (red). Credit: RIKENResearchers at the RIKEN

Gastroenterology April 01,2024