Variants in BRCA1/2 and MMR genes in children with cancer

by Stefan Zorn, Medizinische Hochschule HannoverProfessor Dr. Christian Kratz, initiator of the international study that investigated the cancer risk of disease-relevant variants in BRCA1/2 and MMR ge

Updated on: December 18,2023 12

Variants in BRCA1/2 and MMR genes in children with cancer

by Stefan Zorn, Medizinische Hochschule HannoverProfessor Dr. Christian Kratz, initiator of the international study that investigated the cancer risk of disease-relevant variants in BRCA1/2 and MMR ge

Updated on:December 18,2023 12

'Ray of hope': New advances in fighting a range of cancers

Credit: Pixabay/CC0 Public DomainNew advances in the fight against a range of cancers have been revealed at the annual meeting of the American Society of Clinical Oncology (ASCO), which wraps up in Ch

Updated on: January 10,2024 10

'Ray of hope': New advances in fighting a range of cancers

Credit: Pixabay/CC0 Public DomainNew advances in the fight against a range of cancers have been revealed at the annual meeting of the American Society of Clinical Oncology (ASCO), which wraps up in Ch

Updated on:January 10,2024 10

Research reveals pro-phagocytic function and structural basis of GPR84 signaling

by University of Science and Technology of ChinaGPR84-Gi signaling facilitates cancer cell phagocytosis. Credit:Nature Communications(2023). DOI: 10.1038/s41467-023-41201-0A recent study,

Updated on: January 28,2024 12

Research reveals pro-phagocytic function and structural basis of GPR84 signaling

by University of Science and Technology of ChinaGPR84-Gi signaling facilitates cancer cell phagocytosis. Credit:Nature Communications(2023). DOI: 10.1038/s41467-023-41201-0A recent study,

Updated on:January 28,2024 12

New study suggests 21-gene recurrence score may help in radiation decision-making

by SWOGA new study shows that a test physicians commonly used to guide chemotherapy treatment for post-breast cancer surgery patients may also help them decide whether radiation therapy may be of bene

Updated on: December 20,2023 24

New study suggests 21-gene recurrence score may help in radiation decision-making

by SWOGA new study shows that a test physicians commonly used to guide chemotherapy treatment for post-breast cancer surgery patients may also help them decide whether radiation therapy may be of bene

Updated on:December 20,2023 24

CRISPR-Cas9 datasets analysis leads to largest genetic screen resource for cancer research

byWellcome Trust Sanger InstituteCredit: CC0 Public DomainA comprehensive map of genes necessary for cancer survival is one step closer, following the validation of the two largest CRISPR-Cas9 g

Updated on: December 22,2023 12

CRISPR-Cas9 datasets analysis leads to largest genetic screen resource for cancer research

byWellcome Trust Sanger InstituteCredit: CC0 Public DomainA comprehensive map of genes necessary for cancer survival is one step closer, following the validation of the two largest CRISPR-Cas9 g

Updated on:December 22,2023 12

Combination drug therapy shows promise for a treatment-resistant cancer

by Johns Hopkins University School of MedicineChristine Pratilas, M.D., in the lab. Credit: Frederick W. Dubs, Johns Hopkins Pathology Photography & GraphicsA combination of two cancer drugs

Updated on: May 21,2024 4

Combination drug therapy shows promise for a treatment-resistant cancer

by Johns Hopkins University School of MedicineChristine Pratilas, M.D., in the lab. Credit: Frederick W. Dubs, Johns Hopkins Pathology Photography & GraphicsA combination of two cancer drugs

Updated on:May 21,2024 4

Study offers proof of concept for treating pediatric brain tumors with immunotherapy

by Children’s Hospital of PhiladelphiaGPC2 is expressed in pediatric brain tumors. (A) GPC2 RNA sequencing data across OpenPBTA pediatric brain tumors cohorts. Neuroblastoma GPC2 RNA sequencing includ

Updated on: February 20,2024 14

Study offers proof of concept for treating pediatric brain tumors with immunotherapy

by Children’s Hospital of PhiladelphiaGPC2 is expressed in pediatric brain tumors. (A) GPC2 RNA sequencing data across OpenPBTA pediatric brain tumors cohorts. Neuroblastoma GPC2 RNA sequencing includ

Updated on:February 20,2024 14

Looking at the role epigenetics plays in the ways cancer behaves

by Bob Yirka , Medical XpressGenetic control of expression with eQTL. a, The number of genes with significant models for each data type. b, Distribution of regression coefficients (effect sizes) for e

Updated on: December 27,2023 12

Looking at the role epigenetics plays in the ways cancer behaves

by Bob Yirka , Medical XpressGenetic control of expression with eQTL. a, The number of genes with significant models for each data type. b, Distribution of regression coefficients (effect sizes) for e

Updated on:December 27,2023 12

Scientists discover metabolic feature that allows melanoma cells to spread

by Katie Regan,UT Southwestern Medical CenterResearchers involved in the study include (from left) Drs. Brandon Faubert, Alpaslan Tasdogan, Sean Morrison, and Ralph DeBerardinis. Credit: UTSWRes

Updated on: December 23,2023 16

Scientists discover metabolic feature that allows melanoma cells to spread

by Katie Regan,UT Southwestern Medical CenterResearchers involved in the study include (from left) Drs. Brandon Faubert, Alpaslan Tasdogan, Sean Morrison, and Ralph DeBerardinis. Credit: UTSWRes

Updated on:December 23,2023 16

A potential therapy to reduce the side effects of chemotherapy

byInstitut National de la Sante et de la Recherche MedicaleGraphical abstract. Credit:Journal of Clinical Investigation(2022). DOI: 10.1172/JCI152924Cisplatin is a chemotherapy indic

Updated on: December 26,2023 11

A potential therapy to reduce the side effects of chemotherapy

byInstitut National de la Sante et de la Recherche MedicaleGraphical abstract. Credit:Journal of Clinical Investigation(2022). DOI: 10.1172/JCI152924Cisplatin is a chemotherapy indic

Updated on:December 26,2023 11

New imaging system and artificial intelligence algorithm accurately identify brain tumors

byNYU Langone HealthStimulated Raman histologic images of diffuse astrocytoma (left) and meningioma (right). Credit: Daniel Orringer, NYU Langone HealthA novel method of combining advanced optic

Updated on: December 22,2023 11

New imaging system and artificial intelligence algorithm accurately identify brain tumors

byNYU Langone HealthStimulated Raman histologic images of diffuse astrocytoma (left) and meningioma (right). Credit: Daniel Orringer, NYU Langone HealthA novel method of combining advanced optic

Updated on:December 22,2023 11

Two genes slow down the development of intestinal tumors

byThe Francis Crick InstituteImage of two intestinaltumours, one a control (top) and one with the genes NEDD4 and NEDD4L deleted (bottom). Credit: The Francis Crick InstituteBenign i

Updated on: December 22,2023 12

Two genes slow down the development of intestinal tumors

byThe Francis Crick InstituteImage of two intestinaltumours, one a control (top) and one with the genes NEDD4 and NEDD4L deleted (bottom). Credit: The Francis Crick InstituteBenign i

Updated on:December 22,2023 12