Entrectinib effective, well-tolerated against ROS1 and NTRK lung cancers, especially with brain metastases

by Garth Sundem,CU Anschutz Medical CampusRobert C. Doebele, MD, PhD. Credit: CU Anschutz Medical CampusPooled analysis of three phase 1 and 2 clinical trials published online ahead of print in

Updated on: December 22,2023 10

Entrectinib effective, well-tolerated against ROS1 and NTRK lung cancers, especially with brain metastases

by Garth Sundem,CU Anschutz Medical CampusRobert C. Doebele, MD, PhD. Credit: CU Anschutz Medical CampusPooled analysis of three phase 1 and 2 clinical trials published online ahead of print in

Updated on:December 22,2023 10

B-Cell Lymphoma Treatment Options

B-Cell Lymphoma Treatment OptionsByJennifer Sabour, MSPublished on March 07, 2022Medically reviewed byDoru Paul, MDWhile B-cell lymphoma always originates in white blood cells

Updated on: January 28,2024 0

B-Cell Lymphoma Treatment Options

B-Cell Lymphoma Treatment OptionsByJennifer Sabour, MSPublished on March 07, 2022Medically reviewed byDoru Paul, MDWhile B-cell lymphoma always originates in white blood cells

Updated on:January 28,2024 0

Scientists uncover novel DNA repair mechanism for key cancer target

byThe Francis Crick InstituteGraphical Abstract. Credit:Molecular Cell(2022). DOI: 10.1016/j.molcel.2022.11.008Scientists at the Francis Crick Institute, in collaboration with Artios

Updated on: December 27,2023 9

Scientists uncover novel DNA repair mechanism for key cancer target

byThe Francis Crick InstituteGraphical Abstract. Credit:Molecular Cell(2022). DOI: 10.1016/j.molcel.2022.11.008Scientists at the Francis Crick Institute, in collaboration with Artios

Updated on:December 27,2023 9

Unique gene signature could help predict response to chemotherapy

byThe Francis Crick InstituteIn vitro anticancer drug screen. a Volcano plots showing differences in IC50 values between RAS high and low CCLE cell lines. Drugs with enriched target annotations

Updated on: December 20,2023 10

Unique gene signature could help predict response to chemotherapy

byThe Francis Crick InstituteIn vitro anticancer drug screen. a Volcano plots showing differences in IC50 values between RAS high and low CCLE cell lines. Drugs with enriched target annotations

Updated on:December 20,2023 10

Free tool simplifies cancer research

byKarolinska InstitutetCredit: CC0 Public DomainEvery cell contains a vast number of proteins, each of which has a specific function, for example, as a receptor for another molecule or an enzyme

Updated on: December 22,2023 18

Free tool simplifies cancer research

byKarolinska InstitutetCredit: CC0 Public DomainEvery cell contains a vast number of proteins, each of which has a specific function, for example, as a receptor for another molecule or an enzyme

Updated on:December 22,2023 18

Antioxidant use during chemotherapy risky for breast cancer patients

by SWOGCredit: CC0 Public DomainBreast cancer patients who take the dietary supplements known as antioxidants, as well as iron, vitamin B12, and omega-3 fatty acids, during chemotherapy may be at incr

Updated on: December 23,2023 24

Antioxidant use during chemotherapy risky for breast cancer patients

by SWOGCredit: CC0 Public DomainBreast cancer patients who take the dietary supplements known as antioxidants, as well as iron, vitamin B12, and omega-3 fatty acids, during chemotherapy may be at incr

Updated on:December 23,2023 24

Scientists develop a peptide that targets lung tumors and delivers therapeutics inside cells

bySRI InternationalMonomeric and tetrameric MGS4 have similar binding, internalization and subcellular location. a, Binding and internalization of tetrameric MGS4_V1 and monomeric MGS4_V2 on liv

Updated on: December 27,2023 10

Scientists develop a peptide that targets lung tumors and delivers therapeutics inside cells

bySRI InternationalMonomeric and tetrameric MGS4 have similar binding, internalization and subcellular location. a, Binding and internalization of tetrameric MGS4_V1 and monomeric MGS4_V2 on liv

Updated on:December 27,2023 10

Researchers design new hydrogel for more targeted cancer treatments

by Safa Jinje,University of TorontoGraphical abstract. Credit:Materials Today(2022). DOI: 10.1016/j.mattod.2022.01.023University of Toronto researchers have designed a new way to gro

Updated on: December 22,2023 22

Researchers design new hydrogel for more targeted cancer treatments

by Safa Jinje,University of TorontoGraphical abstract. Credit:Materials Today(2022). DOI: 10.1016/j.mattod.2022.01.023University of Toronto researchers have designed a new way to gro

Updated on:December 22,2023 22

Five facts you may not know about brain tumors

by Laura Hegwer,Rush University Medical CenterCredit: Unsplash/CC0 Public DomainBrain tumors scare most people, but there are still reasons to be hopeful if you learn you have an abnormal growth

Updated on: December 23,2023 10

Five facts you may not know about brain tumors

by Laura Hegwer,Rush University Medical CenterCredit: Unsplash/CC0 Public DomainBrain tumors scare most people, but there are still reasons to be hopeful if you learn you have an abnormal growth

Updated on:December 23,2023 10

The architectural role of p53: Early 3D chromatin remodeling to trigger cellular stress response

byJosep Carreras Leukaemia Research InstituteTAD dynamics along p53 activation. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-46666-1The simplest explanation of cancer

Updated on: April 28,2024 0

The architectural role of p53: Early 3D chromatin remodeling to trigger cellular stress response

byJosep Carreras Leukaemia Research InstituteTAD dynamics along p53 activation. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-46666-1The simplest explanation of cancer

Updated on:April 28,2024 0

Financial impacts of cancer found to intensify disease burden among German patients

byEuropean Society for Medical OncologyA study conducted in Germany draws attention to the fact that the socio-economic burden of cancer is real in Europe too, and not only in the context of the

Updated on: December 18,2023 15

Financial impacts of cancer found to intensify disease burden among German patients

byEuropean Society for Medical OncologyA study conducted in Germany draws attention to the fact that the socio-economic burden of cancer is real in Europe too, and not only in the context of the

Updated on:December 18,2023 15

A promising treatment for ovarian cancer

by Erin Matthews,Canadian Light SourceOvary. Credit: Public DomainOver 20,000 women across the U.S. and Canada are diagnosed with ovarian cancer annually. The symptoms of this disease are often

Updated on: March 12,2024 10

A promising treatment for ovarian cancer

by Erin Matthews,Canadian Light SourceOvary. Credit: Public DomainOver 20,000 women across the U.S. and Canada are diagnosed with ovarian cancer annually. The symptoms of this disease are often

Updated on:March 12,2024 10