Toxicity data reveal no safety concerns with S/N1806 bladder cancer trial

by SWOG Cancer Research NetworkCredit: Unsplash/CC0 Public DomainUpdated toxicity data from the ongoing SWOG/NRG 1806 clinical trial, which tests combining chemoradiation therapy with immunotherapy in

Updated on: December 20,2023 10

Toxicity data reveal no safety concerns with S/N1806 bladder cancer trial

by SWOG Cancer Research NetworkCredit: Unsplash/CC0 Public DomainUpdated toxicity data from the ongoing SWOG/NRG 1806 clinical trial, which tests combining chemoradiation therapy with immunotherapy in

Updated on:December 20,2023 10

Tail spin: Study reveals new way to reduce friendly fire in cell therapy

by Bill Hathaway,Yale UniversityIn CAR-T therapy, T cells in blue find antigens (red) and kill cancer cells (purple). But often, antigens attach to other T cells leading other T cells to attack

Updated on: January 08,2024 12

Tail spin: Study reveals new way to reduce friendly fire in cell therapy

by Bill Hathaway,Yale UniversityIn CAR-T therapy, T cells in blue find antigens (red) and kill cancer cells (purple). But often, antigens attach to other T cells leading other T cells to attack

Updated on:January 08,2024 12

Scientists find dramatic rise in anal cancer in Midwest and Southeast

by Caroline Wallace,Medical University of South CarolinaCredit: Unsplash/CC0 Public DomainSouth Carolina is seeing one of the fastest rises in anal cancer incidence among women and anal cancer m

Updated on: December 27,2023 15

Scientists find dramatic rise in anal cancer in Midwest and Southeast

by Caroline Wallace,Medical University of South CarolinaCredit: Unsplash/CC0 Public DomainSouth Carolina is seeing one of the fastest rises in anal cancer incidence among women and anal cancer m

Updated on:December 27,2023 15

Single-cell 'atlas' reveals origin of an aggressive brain tumor

byCincinnati Children's Hospital Medical CenterChartshows that mice with reduced activity of either the SOX11 or HNRNOH1 genes had longer survival times when induced to develop medullo

Updated on: December 20,2023 10

Single-cell 'atlas' reveals origin of an aggressive brain tumor

byCincinnati Children's Hospital Medical CenterChartshows that mice with reduced activity of either the SOX11 or HNRNOH1 genes had longer survival times when induced to develop medullo

Updated on:December 20,2023 10

Cancer cells hijack enhancer DNA to grow faster, study finds

University of Toronto (U of T) researchers have found that cancer cells can enhance tumor growth by hijacking enhancer DNA normally used when tissues and organs are formed. The mechanism, called enhan

Updated on: October 30,2023 25

Cancer cells hijack enhancer DNA to grow faster, study finds

University of Toronto (U of T) researchers have found that cancer cells can enhance tumor growth by hijacking enhancer DNA normally used when tissues and organs are formed. The mechanism, called enhan

Updated on:October 30,2023 25

The Role of Senescent Macrophages in KRAS-Driven Lung Cancer:Insights from Novel p16-FDR Mouse Models and Therapeutic Implications

Updated on: July 27,2024 0

The Role of Senescent Macrophages in KRAS-Driven Lung Cancer:Insights from Novel p16-FDR Mouse Models and Therapeutic Implications

Updated on:July 27,2024 0

Intestinal microorganisms influence white blood cell levels, study finds

by Hokkaido UniversityUnder normal conditions (steady state) neutrophils regulate the gut microbiota. When the number of neutrophils drops (neutropenia), the composition of the gut microbiota cha

Updated on: April 20,2024 12

Intestinal microorganisms influence white blood cell levels, study finds

by Hokkaido UniversityUnder normal conditions (steady state) neutrophils regulate the gut microbiota. When the number of neutrophils drops (neutropenia), the composition of the gut microbiota cha

Updated on:April 20,2024 12

Algorithm offers new way to spot patients likely to respond to immunotherapy

byInstitute of Cancer ResearchOverview of immune selection calculation using SOPRANO. a, Estimates can be performed at the cohort or at the single individual level. b, In each case, it is possib

Updated on: January 04,2024 9

Algorithm offers new way to spot patients likely to respond to immunotherapy

byInstitute of Cancer ResearchOverview of immune selection calculation using SOPRANO. a, Estimates can be performed at the cohort or at the single individual level. b, In each case, it is possib

Updated on:January 04,2024 9

Scientists identify potential drug target for BRCA-mutated tumours

byInstitute of Cancer ResearchCrystal structure of EXD2 exonuclease domain in spacefill format. Credit: Image generated fromPDBA new study has uncovered a previously unknown role for the e

Updated on: December 22,2023 18

Scientists identify potential drug target for BRCA-mutated tumours

byInstitute of Cancer ResearchCrystal structure of EXD2 exonuclease domain in spacefill format. Credit: Image generated fromPDBA new study has uncovered a previously unknown role for the e

Updated on:December 22,2023 18

BCMA-targeted immunotherapy can lead to durable responses in multiple myeloma

byPerelman School of Medicine at the University of PennsylvaniaMicrograph of a plasmacytoma, the histologic correlate of multiple myeloma. H&E stain. Credit: Wikipedia/CC BY-SA 3.0An experim

Updated on: December 22,2023 24

BCMA-targeted immunotherapy can lead to durable responses in multiple myeloma

byPerelman School of Medicine at the University of PennsylvaniaMicrograph of a plasmacytoma, the histologic correlate of multiple myeloma. H&E stain. Credit: Wikipedia/CC BY-SA 3.0An experim

Updated on:December 22,2023 24

3-D mammography detected 34% more breast cancers in screening

byLund UniversityUsing breast tomosynthesis (3D screening) in the image to the left (one of about 50 thin cross-sectional image slices of the breast), you can see an approximately 1 cm-large tum

Updated on: December 18,2023 10

3-D mammography detected 34% more breast cancers in screening

byLund UniversityUsing breast tomosynthesis (3D screening) in the image to the left (one of about 50 thin cross-sectional image slices of the breast), you can see an approximately 1 cm-large tum

Updated on:December 18,2023 10

Structural analysis reveals an unexpected mechanism for a cancer drug

by Tim Stephens,University of California - Santa CruzThe breast cancer drug palbociclib (grey) interacts with its target protein CDK4 (green) in this structural model. Binding of the activator p

Updated on: December 22,2023 22

Structural analysis reveals an unexpected mechanism for a cancer drug

by Tim Stephens,University of California - Santa CruzThe breast cancer drug palbociclib (grey) interacts with its target protein CDK4 (green) in this structural model. Binding of the activator p

Updated on:December 22,2023 22