Tail spin: Study reveals new way to reduce friendly fire in cell therapy

by Bill Hathaway,Yale UniversityIn CAR-T therapy, T cells in blue find antigens (red) and kill cancer cells (purple). But often, antigens attach to other T cells leading other T cells to attack

Updated on: January 08,2024

Tail spin: Study reveals new way to reduce friendly fire in cell therapy

by Bill Hathaway,Yale UniversityIn CAR-T therapy, T cells in blue find antigens (red) and kill cancer cells (purple). But often, antigens attach to other T cells leading other T cells to attack

Updated on:January 08,2024

MicroRNA is the master regulator of the genome—researchers are learning how to harness the way it controls genes

by Andrea Kasinski,The ConversationMicroRNA can silence genes by binding to mRNA. Credit:Kajsa Mollersen/Wikimedia Commons,CC BY-SAThe Earthformed 4.5 billion years ago, and li

Updated on: December 20,2023

MicroRNA is the master regulator of the genome—researchers are learning how to harness the way it controls genes

by Andrea Kasinski,The ConversationMicroRNA can silence genes by binding to mRNA. Credit:Kajsa Mollersen/Wikimedia Commons,CC BY-SAThe Earthformed 4.5 billion years ago, and li

Updated on:December 20,2023

Analysis of radiotherapy and locoregional recurrence in RxPONDER patients

by SWOG Cancer Research NetworkCredit: Unsplash/CC0 Public DomainAn analysis of data on the use of radiation therapy in a large clinical trial of patients with HR+, HER2- breast cancer who had one to

Updated on: December 17,2023

Analysis of radiotherapy and locoregional recurrence in RxPONDER patients

by SWOG Cancer Research NetworkCredit: Unsplash/CC0 Public DomainAn analysis of data on the use of radiation therapy in a large clinical trial of patients with HR+, HER2- breast cancer who had one to

Updated on:December 17,2023

Basic research opens up new therapeutic opportunities for fighting leukemia

byUniversity of Veterinary Medicine—ViennaGenome-wide CRISPR/Cas9-based loss-of-function screen identifies genetic dependencies of STAT3Y640F-driven cells a) Schematic illustration of a competit

Updated on: December 25,2023

Basic research opens up new therapeutic opportunities for fighting leukemia

byUniversity of Veterinary Medicine—ViennaGenome-wide CRISPR/Cas9-based loss-of-function screen identifies genetic dependencies of STAT3Y640F-driven cells a) Schematic illustration of a competit

Updated on:December 25,2023

HDAC6 score found to predict the response of some cancers to ricolinostat

by Bob Yirka , Medical XpressHDAC6 score in BC. (a) The number of samples and dataset of origin used to evaluate the HDAC6 regulon. (b) Overlap of the original and updated HDAC6 regulons. P value was

Updated on: December 21,2023

HDAC6 score found to predict the response of some cancers to ricolinostat

by Bob Yirka , Medical XpressHDAC6 score in BC. (a) The number of samples and dataset of origin used to evaluate the HDAC6 regulon. (b) Overlap of the original and updated HDAC6 regulons. P value was

Updated on:December 21,2023

Survey: Most women unaware of the signs of an aggressive form of breast cancer

by Ohio State University Comprehensive Cancer CenterDr. Ko Un Park consults with a patient at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Sol

Updated on: December 20,2023

Survey: Most women unaware of the signs of an aggressive form of breast cancer

by Ohio State University Comprehensive Cancer CenterDr. Ko Un Park consults with a patient at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Sol

Updated on:December 20,2023

Clinical trial reveals new subtypes of advanced pancreatic cancer

by Ontario Institute for Cancer ResearchDrs. Faiyaz Notta and Steven Gallinger in a laboratory. Credit: OICRResearchers at the Ontario Institute for Cancer Research (OICR) and the University Health Ne

Updated on: December 20,2023

Clinical trial reveals new subtypes of advanced pancreatic cancer

by Ontario Institute for Cancer ResearchDrs. Faiyaz Notta and Steven Gallinger in a laboratory. Credit: OICRResearchers at the Ontario Institute for Cancer Research (OICR) and the University Health Ne

Updated on:December 20,2023

Researchers identify an Achilles' heel in neuroblastoma

by Molly Chiu,Baylor College of MedicineThe image shows magnified neuroblastoma cells. Credit: Baylor College of MedicineNeuroblastoma, a childhood cancer that develops from neural cells on the

Updated on: December 18,2023

Researchers identify an Achilles' heel in neuroblastoma

by Molly Chiu,Baylor College of MedicineThe image shows magnified neuroblastoma cells. Credit: Baylor College of MedicineNeuroblastoma, a childhood cancer that develops from neural cells on the

Updated on:December 18,2023

Controlling a cancer-associated gene can mimic muscle growth from exercise

byUniversity of ArkansasTranscriptional similarities between human RE recovery and MYC overexpression in mouse plantaris muscle. Credit:EMBO Reports(2024). DOI: 10.1038/s44319-024-00

Updated on: December 12,2024

Controlling a cancer-associated gene can mimic muscle growth from exercise

byUniversity of ArkansasTranscriptional similarities between human RE recovery and MYC overexpression in mouse plantaris muscle. Credit:EMBO Reports(2024). DOI: 10.1038/s44319-024-00

Updated on:December 12,2024

Analyzing a Study on the Therapeutic Potential of Targeting IL-20RB in Lung Cancer Bone Metastasis

Updated on: September 15,2024

Analyzing a Study on the Therapeutic Potential of Targeting IL-20RB in Lung Cancer Bone Metastasis

Updated on:September 15,2024

New fast, effective way to detect cancer stem cells

New fast, effective way to detect cancer stem cellsby Fram Dinshaw,McMaster UniversityGraphical abstract. Credit:Cell Reports Medicine(2023). DOI: 10.1016/j.xcrm.2023.101108McMaster

Updated on: October 28,2023

New fast, effective way to detect cancer stem cells

New fast, effective way to detect cancer stem cellsby Fram Dinshaw,McMaster UniversityGraphical abstract. Credit:Cell Reports Medicine(2023). DOI: 10.1016/j.xcrm.2023.101108McMaster

Updated on:October 28,2023

Multicancer early detection feasible for outpatients

A blood-based multicancer early detection (MCED) test using cell-free DNA (cfDNA) is feasible for outpatients and has a positive predictive value of about 40 percent, according to a study presented at

Updated on: December 21,2023

Multicancer early detection feasible for outpatients

A blood-based multicancer early detection (MCED) test using cell-free DNA (cfDNA) is feasible for outpatients and has a positive predictive value of about 40 percent, according to a study presented at

Updated on:December 21,2023