Pembrolizumab Active in Advanced Nasopharyngeal Carcinoma

August 29, 2017Jason HarrisPembrolizumab (Keytruda) induced an overall response rate of 25.9% and was well tolerated in patients with PD-L1–positive recurrent or metastatic nasopharyngeal carcinoma.Na

Updated on: October 24,2023 76

Pembrolizumab Active in Advanced Nasopharyngeal Carcinoma

August 29, 2017Jason HarrisPembrolizumab (Keytruda) induced an overall response rate of 25.9% and was well tolerated in patients with PD-L1–positive recurrent or metastatic nasopharyngeal carcinoma.Na

Updated on:October 24,2023 76

New technology in recent clinical study aims toward earlier detection of hepatocellular carcinoma

byUniversity of California, Los AngelesCredit: Pixabay/CC0 Public DomainPrimary liver cancer, the third-leading cause of cancer-related death worldwide, takes more than 30,000 lives in the Unite

Updated on: December 18,2023 14

New technology in recent clinical study aims toward earlier detection of hepatocellular carcinoma

byUniversity of California, Los AngelesCredit: Pixabay/CC0 Public DomainPrimary liver cancer, the third-leading cause of cancer-related death worldwide, takes more than 30,000 lives in the Unite

Updated on:December 18,2023 14

Larotrectinib in tumours with NTRK gene fusion: Data are not yet sufficient

byInstitute for Quality and Efficiency in Health CareCredit: Institute for Quality and Efficiency in Health CareIn the summer of 2019, larotrectinib was approved as the first drug in Europe to b

Updated on: December 20,2023 19

Larotrectinib in tumours with NTRK gene fusion: Data are not yet sufficient

byInstitute for Quality and Efficiency in Health CareCredit: Institute for Quality and Efficiency in Health CareIn the summer of 2019, larotrectinib was approved as the first drug in Europe to b

Updated on:December 20,2023 19

Marker for therapy response in acute myeloid leukemia identified

byGerman Cancer Research CenterCell line sensitivity and additional patient data. A IC50s for VEN of 19 AML cell lines classified as primitive (Prim-AML, n = 11) or monocytic (Mono-AML, n = 8) t

Updated on: December 21,2023 10

Marker for therapy response in acute myeloid leukemia identified

byGerman Cancer Research CenterCell line sensitivity and additional patient data. A IC50s for VEN of 19 AML cell lines classified as primitive (Prim-AML, n = 11) or monocytic (Mono-AML, n = 8) t

Updated on:December 21,2023 10

Protective mutation shown to impair esophagus tumor growth

byWellcome Trust Sanger InstituteDifferentiation and homeostasis in aged Notch1 mutant mouse tissue. a, YFPCreNotch1flox/floxmice were induced at high dose so mutant cells rapidly covered

Updated on: December 19,2023 15

Protective mutation shown to impair esophagus tumor growth

byWellcome Trust Sanger InstituteDifferentiation and homeostasis in aged Notch1 mutant mouse tissue. a, YFPCreNotch1flox/floxmice were induced at high dose so mutant cells rapidly covered

Updated on:December 19,2023 15

Study identifies genetic cause for some brain tumors

Study identifies genetic cause for some brain tumorsby Olivia Dimmer,Northwestern UniversityMultiplex immunofluorescence staining and imaging using the COMET system platform on a human meningiom

Updated on: October 30,2023 10

Study identifies genetic cause for some brain tumors

Study identifies genetic cause for some brain tumorsby Olivia Dimmer,Northwestern UniversityMultiplex immunofluorescence staining and imaging using the COMET system platform on a human meningiom

Updated on:October 30,2023 10

Newfound mechanism suggests drug combination could starve pancreatic cancer

byNYU Langone HealthPancreatic cancer cells (blue) growing as a sphere encased in membranes (red). Credit: National Cancer InstituteA new combination of treatments safely decreased growth of pan

Updated on: October 14,2023 189

Newfound mechanism suggests drug combination could starve pancreatic cancer

byNYU Langone HealthPancreatic cancer cells (blue) growing as a sphere encased in membranes (red). Credit: National Cancer InstituteA new combination of treatments safely decreased growth of pan

Updated on:October 14,2023 189

Chinese medicine ingredients found to generate autophagic flux to suppress tumor progression in gastric cancer

byScience China PressActivation of Beclin-1 by piceatannol promotes autophagic flux in GC cells, and combined with everolimus, triggers autophagic death, ultimately inhibiting tumor progression,

Updated on: December 21,2023 10

Chinese medicine ingredients found to generate autophagic flux to suppress tumor progression in gastric cancer

byScience China PressActivation of Beclin-1 by piceatannol promotes autophagic flux in GC cells, and combined with everolimus, triggers autophagic death, ultimately inhibiting tumor progression,

Updated on:December 21,2023 10

Olaparib and adavosertib work best when given sequentially for DNA-damage response mutations in advanced tumors

by European Organisation for Research and Treatment of CancerCredit: Pixabay/CC0 Public DomainPatients with cancers that are driven by certain mutations occurring in response to DNA damage can be safe

Updated on: December 19,2023 10

Olaparib and adavosertib work best when given sequentially for DNA-damage response mutations in advanced tumors

by European Organisation for Research and Treatment of CancerCredit: Pixabay/CC0 Public DomainPatients with cancers that are driven by certain mutations occurring in response to DNA damage can be safe

Updated on:December 19,2023 10

Discovery of small molecule Gαq/11 protein inhibitors against uveal melanoma

by Compuscript LtdGraphical abstract:Constitutively activated Gαq/11 proteins drive the vast majority of uveal melanoma (UM). GQ262 effectively combats UM both in vitro and in vivo by targeting Gαq/11

Updated on: December 21,2023 7

Discovery of small molecule Gαq/11 protein inhibitors against uveal melanoma

by Compuscript LtdGraphical abstract:Constitutively activated Gαq/11 proteins drive the vast majority of uveal melanoma (UM). GQ262 effectively combats UM both in vitro and in vivo by targeting Gαq/11

Updated on:December 21,2023 7

Personalised blood test could help predict which lung cancers might return

byGraeme Sneddon| News1 April 2022Patients who are at a higher risk of their lung cancer returning can be identified by a personalised blood test that is performed after treatment, accordi

Updated on: December 19,2023 24

Personalised blood test could help predict which lung cancers might return

byGraeme Sneddon| News1 April 2022Patients who are at a higher risk of their lung cancer returning can be identified by a personalised blood test that is performed after treatment, accordi

Updated on:December 19,2023 24

Study points to new possibilities for treating lung cancer patients

by Birgitte Svennevig,University of Southern DenmarkAn EMT-centric investigation of metabolic processes in a comprehensive lung cancer transcriptome profiles collection identified an inverse ass

Updated on: May 25,2024 5

Study points to new possibilities for treating lung cancer patients

by Birgitte Svennevig,University of Southern DenmarkAn EMT-centric investigation of metabolic processes in a comprehensive lung cancer transcriptome profiles collection identified an inverse ass

Updated on:May 25,2024 5