Team establishes a large collection of cholangiocarcinoma models for preclinical drug evaluation and biomarker discovery

by Vall d'Hebron Institute of OncologyCholangiocarcinomas (CCAs) are a highly aggressive and diverse group of malignancies of the biliary tract that currently account for 15% of all liver cancers

Updated on: January 08,2024 10

Team establishes a large collection of cholangiocarcinoma models for preclinical drug evaluation and biomarker discovery

by Vall d'Hebron Institute of OncologyCholangiocarcinomas (CCAs) are a highly aggressive and diverse group of malignancies of the biliary tract that currently account for 15% of all liver cancers

Updated on:January 08,2024 10

Researchers identify potential gene marker for treating pancreatic cancer

by Joe Dangor,Mayo ClinicCredit: Mayo ClinicResearchers at Mayo Clinic Comprehensive Cancer Center have identified a gene marker that may lead to a more effective, precision treatment for pancre

Updated on: January 30,2024 19

Researchers identify potential gene marker for treating pancreatic cancer

by Joe Dangor,Mayo ClinicCredit: Mayo ClinicResearchers at Mayo Clinic Comprehensive Cancer Center have identified a gene marker that may lead to a more effective, precision treatment for pancre

Updated on:January 30,2024 19

Study validates first-ever predictive AI biomarker of androgen deprivation therapy benefit in prostate cancer

by University Hospitals Cleveland Medical CenterProstate cancer cells. Credit: NIH Image GalleryData from a new study published inNEJM Evidenceshows promise for personalized use of sh

Updated on: February 20,2024 14

Study validates first-ever predictive AI biomarker of androgen deprivation therapy benefit in prostate cancer

by University Hospitals Cleveland Medical CenterProstate cancer cells. Credit: NIH Image GalleryData from a new study published inNEJM Evidenceshows promise for personalized use of sh

Updated on:February 20,2024 14

New delivery strategy may improve chemotherapy for acute myeloid leukemia

byWileyCNL augments the efficacy of cytarabine/venetoclax treatment in in vivo AML models. (A–C) Bioluminescence images (A), their quantification (B) and survival of MOLM-13 Luc-YFP bearing NRG

Updated on: January 11,2024 15

New delivery strategy may improve chemotherapy for acute myeloid leukemia

byWileyCNL augments the efficacy of cytarabine/venetoclax treatment in in vivo AML models. (A–C) Bioluminescence images (A), their quantification (B) and survival of MOLM-13 Luc-YFP bearing NRG

Updated on:January 11,2024 15

Researchers develop CAR T cells that fight prostate cancer in bone

by H. Lee Moffitt Cancer Center & Research InstituteBTN expression and spontaneous gamma/delta T cell infiltration in prostate tumors. (A) Bioinformatic analysis of TCR gamma variable regions

Updated on: February 20,2024 13

Researchers develop CAR T cells that fight prostate cancer in bone

by H. Lee Moffitt Cancer Center & Research InstituteBTN expression and spontaneous gamma/delta T cell infiltration in prostate tumors. (A) Bioinformatic analysis of TCR gamma variable regions

Updated on:February 20,2024 13

Breast cancer risk models may incorrectly classify many women

byUniversity of California, Los AngelesCredit: Unsplash/CC0 Public DomainBreast cancer risk estimates for individual women vary substantially depending on which risk assessment model is used, an

Updated on: January 02,2024 12

Breast cancer risk models may incorrectly classify many women

byUniversity of California, Los AngelesCredit: Unsplash/CC0 Public DomainBreast cancer risk estimates for individual women vary substantially depending on which risk assessment model is used, an

Updated on:January 02,2024 12

Testosterone therapy may protect against breast cancer in trans masculine individuals

by Jacqueline Mitchell,Beth Israel Deaconess Medical Centera) Lobular atrophy was assessed by the pathologists using four categories. b) The duration of testosterone therapy (TT) significantly c

Updated on: August 03,2024 0

Testosterone therapy may protect against breast cancer in trans masculine individuals

by Jacqueline Mitchell,Beth Israel Deaconess Medical Centera) Lobular atrophy was assessed by the pathologists using four categories. b) The duration of testosterone therapy (TT) significantly c

Updated on:August 03,2024 0

Drugs for invasive breast cancer 'could treat earliest stages of the disease'

by Emma Thorne,University of NottinghamMicrograph showing a lymph node invaded by ductal breast carcinoma, with extension of the tumour beyond the lymph node. Credit: Nephron/WikipediaDrug

Updated on: April 10,2024 18

Drugs for invasive breast cancer 'could treat earliest stages of the disease'

by Emma Thorne,University of NottinghamMicrograph showing a lymph node invaded by ductal breast carcinoma, with extension of the tumour beyond the lymph node. Credit: Nephron/WikipediaDrug

Updated on:April 10,2024 18

Non-invasive device more effective for early detection of lymphedema after breast cancer

byCleveland ClinicCredit: Cleveland ClinicSome breast cancer survivors may experience lymphedema, a condition that causes painful swelling of their arm or hand after undergoing surgery or radiat

Updated on: January 10,2024 10

Non-invasive device more effective for early detection of lymphedema after breast cancer

byCleveland ClinicCredit: Cleveland ClinicSome breast cancer survivors may experience lymphedema, a condition that causes painful swelling of their arm or hand after undergoing surgery or radiat

Updated on:January 10,2024 10

Breakthrough in understanding of how cancer spreads could lead to better treatments

by Cancer Research UKNALCN loss-of-function in aggressive cancers.a, Differential gene expression between normal PROM1+gastric cells andP1KP-GAC cells (downregulated ion channels are

Updated on: February 18,2024 13

Breakthrough in understanding of how cancer spreads could lead to better treatments

by Cancer Research UKNALCN loss-of-function in aggressive cancers.a, Differential gene expression between normal PROM1+gastric cells andP1KP-GAC cells (downregulated ion channels are

Updated on:February 18,2024 13

A comprehensive proteogenomic dataset to help cancer researchers unravel molecular mysteries

by National Institutes of HealthTumor types and data types of the CPTAC pan-cancer dataset. Overview of the available molecular data types for the CPTAC pan-cancer cohort (n= 1072, see Tabl

Updated on: February 20,2024 12

A comprehensive proteogenomic dataset to help cancer researchers unravel molecular mysteries

by National Institutes of HealthTumor types and data types of the CPTAC pan-cancer dataset. Overview of the available molecular data types for the CPTAC pan-cancer cohort (n= 1072, see Tabl

Updated on:February 20,2024 12

Comparison of survival times of advanced cancer patients with palliative care at home and in hospital

byUniversity of TsukubaCredit: AI-generated imageThe location where cancer patients spend their last days can affect their "quality of death." However, it remains unclear whether the l

Updated on: January 08,2024 12

Comparison of survival times of advanced cancer patients with palliative care at home and in hospital

byUniversity of TsukubaCredit: AI-generated imageThe location where cancer patients spend their last days can affect their "quality of death." However, it remains unclear whether the l

Updated on:January 08,2024 12