Targeting cancer's hidden master regulators

by Columbia University Irving Medical CenterSchematic of the VIPER (A), OncoTarget (B), and OncoTreat (C) methodologies. G.E.S.: gene expression signature. MoR: mode of regulation—i.e., genes who

Updated on: April 14,2024 15

Targeting cancer's hidden master regulators

by Columbia University Irving Medical CenterSchematic of the VIPER (A), OncoTarget (B), and OncoTreat (C) methodologies. G.E.S.: gene expression signature. MoR: mode of regulation—i.e., genes who

Updated on:April 14,2024 15

Thalidomide reveals path for targeting undruggable transcription factors for cancer treatment

by Tom Ulrich,Broad Institute of MIT and HarvardCredit: Susanna M. Hamilton, Broad CommunicationsThalidomide, a morning-sickness drug recalled in the 1960s because it caused devastating birth de

Updated on: March 06,2024 19

Thalidomide reveals path for targeting undruggable transcription factors for cancer treatment

by Tom Ulrich,Broad Institute of MIT and HarvardCredit: Susanna M. Hamilton, Broad CommunicationsThalidomide, a morning-sickness drug recalled in the 1960s because it caused devastating birth de

Updated on:March 06,2024 19

Researchers analyze cancer discrepancies among young Black men in the South

by Vinod Hopson,University of Texas Health Science Center at HoustonRegional Kaposi sarcoma incidence rate trends in non-Hispanic White men aged 20-34. Abbreviation: AAPC, average annual percent

Updated on: January 30,2024 14

Researchers analyze cancer discrepancies among young Black men in the South

by Vinod Hopson,University of Texas Health Science Center at HoustonRegional Kaposi sarcoma incidence rate trends in non-Hispanic White men aged 20-34. Abbreviation: AAPC, average annual percent

Updated on:January 30,2024 14

New framework for using AI in health care considers medical knowledge, practices, procedures, values

by Carnegie Mellon UniversityCredit: Pixabay/CC0 Public DomainHealth care organizations are looking to artificial intelligence (AI) tools to improve patient care, but their translation into clini

Updated on: April 22,2024 20

New framework for using AI in health care considers medical knowledge, practices, procedures, values

by Carnegie Mellon UniversityCredit: Pixabay/CC0 Public DomainHealth care organizations are looking to artificial intelligence (AI) tools to improve patient care, but their translation into clini

Updated on:April 22,2024 20

Study finds Medicaid expansion improves cancer survival outcomes for young adults

byEmory UniversityCredit: Unsplash/CC0 Public DomainA large first-of-its-kind study reported in theJournal of Clinical Oncologyfinds that expanded Medicaid coverage under the Afforda

Updated on: January 23,2024 13

Study finds Medicaid expansion improves cancer survival outcomes for young adults

byEmory UniversityCredit: Unsplash/CC0 Public DomainA large first-of-its-kind study reported in theJournal of Clinical Oncologyfinds that expanded Medicaid coverage under the Afforda

Updated on:January 23,2024 13

Chemotherapy before surgery helps patients with nose and sinus cancer avoid debilitating eye and bone removal

by ECOG-ACRIN Cancer Research GroupCredit: CC0 Public DomainResults from a clinical trial by the ECOG-ACRIN Cancer Research Group (ECOG-ACRIN) show a striking improvement for patients who received che

Updated on: September 28,2024 0

Chemotherapy before surgery helps patients with nose and sinus cancer avoid debilitating eye and bone removal

by ECOG-ACRIN Cancer Research GroupCredit: CC0 Public DomainResults from a clinical trial by the ECOG-ACRIN Cancer Research Group (ECOG-ACRIN) show a striking improvement for patients who received che

Updated on:September 28,2024 0

FDA Approves Two Cell-Based SCD Gene Therapies

February 2024The U.S. Food and Drug Administration (FDA) approved exagamglogene autotemcel (exa-cel) and lovotibeglogene autotemcel (lovo-cel) for the treatment of sickle cell disease (SCD) in patient

Updated on: February 18,2024 6

FDA Approves Two Cell-Based SCD Gene Therapies

February 2024The U.S. Food and Drug Administration (FDA) approved exagamglogene autotemcel (exa-cel) and lovotibeglogene autotemcel (lovo-cel) for the treatment of sickle cell disease (SCD) in patient

Updated on:February 18,2024 6

Inflammatory-nutritional score helps predict survival in new multiple myeloma

by Elana GotkineFor patients with newly diagnosed multiple myeloma (NDMM), a nomogram based on the inflammatory-nutritional score (INS) may help to predict survival, according to a study published onl

Updated on: January 16,2024 14

Inflammatory-nutritional score helps predict survival in new multiple myeloma

by Elana GotkineFor patients with newly diagnosed multiple myeloma (NDMM), a nomogram based on the inflammatory-nutritional score (INS) may help to predict survival, according to a study published onl

Updated on:January 16,2024 14

Treatment found to reduce progression of rare blood cancer by 74%

Credit: Wikimedia CommonsA treatment that involves genetically modifying the body's own immune cells has been found to cut the risk of disease progression by 74 percent in people with a rare type

Updated on: January 29,2024 11

Treatment found to reduce progression of rare blood cancer by 74%

Credit: Wikimedia CommonsA treatment that involves genetically modifying the body's own immune cells has been found to cut the risk of disease progression by 74 percent in people with a rare type

Updated on:January 29,2024 11

Automated bone scan index prognostic for prostate cancer

(HealthDay)—The automated Bone Scan Index (aBSI) is an independent prognostic imaging biomarker of overall survival (OS) in metastatic castration-resistant prostate cancer (mCRPC), according to a stud

Updated on: April 01,2024 13

Automated bone scan index prognostic for prostate cancer

(HealthDay)—The automated Bone Scan Index (aBSI) is an independent prognostic imaging biomarker of overall survival (OS) in metastatic castration-resistant prostate cancer (mCRPC), according to a stud

Updated on:April 01,2024 13

Study identifies novel epigenetic changes in pediatric brain cancer

by Melissa Rohman,Northwestern UniversityDNA methylation and transcriptomic landscape of recurrent ependymoma tumors. A Time-course summary of surgery, radio- and chemotherapy treatment and tumo

Updated on: February 23,2024 13

Study identifies novel epigenetic changes in pediatric brain cancer

by Melissa Rohman,Northwestern UniversityDNA methylation and transcriptomic landscape of recurrent ependymoma tumors. A Time-course summary of surgery, radio- and chemotherapy treatment and tumo

Updated on:February 23,2024 13

Researchers identify a gene as a potential target in treatment-resistant brain cancer glioblastoma multiforme

by University of California, Los AngelesSingle-cell sequencing reveals the diverse functional states of glioma cells post-radiation.aUMAP plot of cell clusters from control (0 Gy) and

Updated on: February 23,2024 19

Researchers identify a gene as a potential target in treatment-resistant brain cancer glioblastoma multiforme

by University of California, Los AngelesSingle-cell sequencing reveals the diverse functional states of glioma cells post-radiation.aUMAP plot of cell clusters from control (0 Gy) and

Updated on:February 23,2024 19