An elusive mechanism of wasting syndrome cachexia revealed

by Justin Jackson , Medical XpressOSM induces Eda2r expression in muscle and the depletion of OSMR protects from muscle wasting. a, Mouse primary myotubes were treated with recombinant TNFα, IL-6, LIF

Updated on: February 01,2024 16

An elusive mechanism of wasting syndrome cachexia revealed

by Justin Jackson , Medical XpressOSM induces Eda2r expression in muscle and the depletion of OSMR protects from muscle wasting. a, Mouse primary myotubes were treated with recombinant TNFα, IL-6, LIF

Updated on:February 01,2024 16

Researchers revisit potent drug as promising treatment for acute leukemia

by National University of SingaporeChemical screening using the GIMAP enhancer reporter system. (A) Overview of the chemical screening strategy. Using a liquid handling workstation, 2,961 compoun

Updated on: February 03,2024 11

Researchers revisit potent drug as promising treatment for acute leukemia

by National University of SingaporeChemical screening using the GIMAP enhancer reporter system. (A) Overview of the chemical screening strategy. Using a liquid handling workstation, 2,961 compoun

Updated on:February 03,2024 11

Study finds new, unexpected mechanism of cancer cell spread

by Keck School of Medicine of USCResearchers from the Keck School of Medicine of USC used imaging techniques to study how the protein GRP78 controls cancer cell behavior. In the top row, human lu

Updated on: January 30,2024 17

Study finds new, unexpected mechanism of cancer cell spread

by Keck School of Medicine of USCResearchers from the Keck School of Medicine of USC used imaging techniques to study how the protein GRP78 controls cancer cell behavior. In the top row, human lu

Updated on:January 30,2024 17

How 'paralyzed' immune cells can be reactivated against brain tumors

by German Cancer Research CenterGlioma of the left parietal lobe. CT scan with contrast enhancement. Credit: Mikhail Kalinin/CC BY-SA 3.0Brain tumor cells with a certain common mutation reprogram

Updated on: April 01,2024 11

How 'paralyzed' immune cells can be reactivated against brain tumors

by German Cancer Research CenterGlioma of the left parietal lobe. CT scan with contrast enhancement. Credit: Mikhail Kalinin/CC BY-SA 3.0Brain tumor cells with a certain common mutation reprogram

Updated on:April 01,2024 11

New therapeutic approach for the treatment of neuroblastoma in young children

by Jonas Machner, Universitätsmedizin HalleLead author Sven Hagemann is handling cell cultures. Credit: University Medicine HalleNeuroblastomas are tumors of the nervous system. They can form in many

Updated on: February 18,2024 17

New therapeutic approach for the treatment of neuroblastoma in young children

by Jonas Machner, Universitätsmedizin HalleLead author Sven Hagemann is handling cell cultures. Credit: University Medicine HalleNeuroblastomas are tumors of the nervous system. They can form in many

Updated on:February 18,2024 17

Leukemia treatment breakthrough for babies

by Hayley Jarvis,Brunel UniversityComparison of K562-t(7;12) transcriptional landscape with t(7;12) patient signatures. A 177-gene signature of t(7;12)-patient gene expression extrapolated from

Updated on: February 23,2024 16

Leukemia treatment breakthrough for babies

by Hayley Jarvis,Brunel UniversityComparison of K562-t(7;12) transcriptional landscape with t(7;12) patient signatures. A 177-gene signature of t(7;12)-patient gene expression extrapolated from

Updated on:February 23,2024 16

Team develops tools and techniques to explore cancer signals at the subcellular level

by Jerry Grillo,Georgia Institute of TechnologyGraphical abstract. Credit:iScience(2022). DOI: 10.1016/j.isci.2022.104980This year, about 240,000 people in the U.S. will discover the

Updated on: January 08,2024 9

Team develops tools and techniques to explore cancer signals at the subcellular level

by Jerry Grillo,Georgia Institute of TechnologyGraphical abstract. Credit:iScience(2022). DOI: 10.1016/j.isci.2022.104980This year, about 240,000 people in the U.S. will discover the

Updated on:January 08,2024 9

Researchers show xCT protein is key link in inhibiting pancreatic cancer growth and limiting mood disturbances

by Vrije Universiteit BrusselCredit: Pixabay/CC0 Public DomainThe xCT protein, which plays an important role as a transport molecule in cells, could play a part in cancer treatment in the future, rese

Updated on: March 28,2024 0

Researchers show xCT protein is key link in inhibiting pancreatic cancer growth and limiting mood disturbances

by Vrije Universiteit BrusselCredit: Pixabay/CC0 Public DomainThe xCT protein, which plays an important role as a transport molecule in cells, could play a part in cancer treatment in the future, rese

Updated on:March 28,2024 0

Study gives new insight into how cancer metastasizes to the brain

by The Wistar InstituteIFN signaling is activated in brain metastasis.a–cIFN signaling is activated in both human astrocytes and MDA231-BrM cells by coculture in vitro.N = 2 bio

Updated on: February 20,2024 20

Study gives new insight into how cancer metastasizes to the brain

by The Wistar InstituteIFN signaling is activated in brain metastasis.a–cIFN signaling is activated in both human astrocytes and MDA231-BrM cells by coculture in vitro.N = 2 bio

Updated on:February 20,2024 20

Research uncovers potential pathway for breast cancer treatment

by Elizabeth Chapin,University of KentuckyYadi Wu, Ph.D., University of Kentucky Markey Cancer Center. Credit: Ben Corwin/University of KentuckyA recent University of Kentucky Markey Cancer Cent

Updated on: March 20,2024 13

Research uncovers potential pathway for breast cancer treatment

by Elizabeth Chapin,University of KentuckyYadi Wu, Ph.D., University of Kentucky Markey Cancer Center. Credit: Ben Corwin/University of KentuckyA recent University of Kentucky Markey Cancer Cent

Updated on:March 20,2024 13

Study hints at new target to improve immune therapy in triple-negative breast cancer

by CU Anschutz Medical CampusHeide Ford, PhD, and University of Colorado Cancer Center colleagues show that Eya3 may regulate immune response to triple-negative breast cancer, potentially improvi

Updated on: June 01,2024 8

Study hints at new target to improve immune therapy in triple-negative breast cancer

by CU Anschutz Medical CampusHeide Ford, PhD, and University of Colorado Cancer Center colleagues show that Eya3 may regulate immune response to triple-negative breast cancer, potentially improvi

Updated on:June 01,2024 8

New study discovers pre-treatment cognitive impairment in younger cancer patients

byUniversity of California, IrvineCredit: Unsplash/CC0 Public DomainA team of researchers led by the University of California, Irvine has discovered that adolescent and young adult cancer

Updated on: January 15,2024 14

New study discovers pre-treatment cognitive impairment in younger cancer patients

byUniversity of California, IrvineCredit: Unsplash/CC0 Public DomainA team of researchers led by the University of California, Irvine has discovered that adolescent and young adult cancer

Updated on:January 15,2024 14