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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
Sub Categories on Oncology
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Real-World Data Highlight Utility of Axi-Cel/Tisa-Cel in DLBCL

Real-World Data Highlight Utility of Axi-Cel/Tisa-Cel in DLBCL

June 12, 2021Conor KillmurrayIn the first few years of their availability in the United States, axicabtagene ciloleucel and tisagenlecleucel have been used to mostly treat patients with diffuse large

Real-World Data Highlight Utility of Axi-Cel/Tisa-Cel in DLBCL

June 12, 2021Conor KillmurrayIn the first few years of their availability in the United States, axicabtagene ciloleucel and tisagenlecleucel have been used to mostly treat patients with diffuse large
The phenotypic plasticity effect of cancer cells and how to exploit it

The phenotypic plasticity effect of cancer cells and how to exploit it

by Michael Hesse,Max Planck SocietyMathematical model of tumor heterogeneity and phenotype switching: A detailed analysis. Credit: M.Raatz, MPI for Evolutionary BiologyCancer cells are notorious

The phenotypic plasticity effect of cancer cells and how to exploit it

by Michael Hesse,Max Planck SocietyMathematical model of tumor heterogeneity and phenotype switching: A detailed analysis. Credit: M.Raatz, MPI for Evolutionary BiologyCancer cells are notorious
Splicing deregulation detected and targeted in type of childhood leukemia

Splicing deregulation detected and targeted in type of childhood leukemia

byUniversity of California - San DiegoA micrograph depicts acute myeloid leukemia cells. Though treatments have dramatically advanced, AML in children can become resistant to therapy. New resear

Splicing deregulation detected and targeted in type of childhood leukemia

byUniversity of California - San DiegoA micrograph depicts acute myeloid leukemia cells. Though treatments have dramatically advanced, AML in children can become resistant to therapy. New resear
Out-of-pocket costs for cancer care keep climbing

Out-of-pocket costs for cancer care keep climbing

Cancerpatients already have a lot to deal with emotionally and physically. But research shows that insured patients under 65 are also paying more for their treatments out-of-pocket than ever bef

Out-of-pocket costs for cancer care keep climbing

Cancerpatients already have a lot to deal with emotionally and physically. But research shows that insured patients under 65 are also paying more for their treatments out-of-pocket than ever bef
Tumor Sequencing Identifies Host Signatures Tied to Immunotherapy Response in Advanced RCC

Tumor Sequencing Identifies Host Signatures Tied to Immunotherapy Response in Advanced RCC

July 14, 2023Caroline SeymourHigher levels of baseline TCR clonality in peripheral blood mononuclear cells (PBMCs) and baseline IgG1 fraction in PBMCs and tumor tissue were identified in an institutio

Tumor Sequencing Identifies Host Signatures Tied to Immunotherapy Response in Advanced RCC

July 14, 2023Caroline SeymourHigher levels of baseline TCR clonality in peripheral blood mononuclear cells (PBMCs) and baseline IgG1 fraction in PBMCs and tumor tissue were identified in an institutio
Maveropepimut-S Plus Pembrolizumab and Cyclophosphamide Shows Early Promise in R/R DLBCL

Maveropepimut-S Plus Pembrolizumab and Cyclophosphamide Shows Early Promise in R/R DLBCL

February 13, 2023Kristi RosaThe combination of maveropepimut-S, pembrolizumab, and intermittent low-dose cyclophosphamide elicited responses in patients with relapsed or refractory diffuse large B-cel

Maveropepimut-S Plus Pembrolizumab and Cyclophosphamide Shows Early Promise in R/R DLBCL

February 13, 2023Kristi RosaThe combination of maveropepimut-S, pembrolizumab, and intermittent low-dose cyclophosphamide elicited responses in patients with relapsed or refractory diffuse large B-cel
Can the flu shot help fight cancer?

Can the flu shot help fight cancer?

byRush University Medical CenterCredit: CC0 Public DomainChanging the microenvironment of tumors to increase the immune system's response to them has been the goal of countless research and

Can the flu shot help fight cancer?

byRush University Medical CenterCredit: CC0 Public DomainChanging the microenvironment of tumors to increase the immune system's response to them has been the goal of countless research and
Mechanics of breast cancer metastasis discovered, offering target for treatment

Mechanics of breast cancer metastasis discovered, offering target for treatment

Mechanics of breast cancer metastasis discovered, offering target for treatmentby Adrienne Berard,Pennsylvania State UniversityA human breast cancer cell, adenocarcinoma MDA-MB-231, demonstrates

Mechanics of breast cancer metastasis discovered, offering target for treatment

Mechanics of breast cancer metastasis discovered, offering target for treatmentby Adrienne Berard,Pennsylvania State UniversityA human breast cancer cell, adenocarcinoma MDA-MB-231, demonstrates
CYNK-101 Plus Avelumab Mediates ADCC Activity in Select PD-L1+ Solid Tumors

CYNK-101 Plus Avelumab Mediates ADCC Activity in Select PD-L1+ Solid Tumors

November 13, 2022Gina MauroCYNK-101 demonstrated synergistic activity when used in combination with avelumab through antibody-dependent cellular cytotoxicity against PD-L1–positive non–small cell lung

CYNK-101 Plus Avelumab Mediates ADCC Activity in Select PD-L1+ Solid Tumors

November 13, 2022Gina MauroCYNK-101 demonstrated synergistic activity when used in combination with avelumab through antibody-dependent cellular cytotoxicity against PD-L1–positive non–small cell lung
Comparing DNA changes in blood stem cells and leukemia cells could help pick out children with high-risk AML

Comparing DNA changes in blood stem cells and leukemia cells could help pick out children with high-risk AML

Credit: Unsplash/CC0 Public DomainIn some children with acute myeloid leukemia, cancer cells have as many DNA changes as healthy blood stem cells. Researchers were surprised to find these children hav

Comparing DNA changes in blood stem cells and leukemia cells could help pick out children with high-risk AML

Credit: Unsplash/CC0 Public DomainIn some children with acute myeloid leukemia, cancer cells have as many DNA changes as healthy blood stem cells. Researchers were surprised to find these children hav
Is AI Ready to Play a Leading Role in Colorectal Cancer Screening?

Is AI Ready to Play a Leading Role in Colorectal Cancer Screening?

by Sharon ReynoldsArtificial intelligence, or AI, is suddenly everywhere. From ChatGPT to automated customer service "representatives,” the ability of computers to perform increasingly complicate

Is AI Ready to Play a Leading Role in Colorectal Cancer Screening?

by Sharon ReynoldsArtificial intelligence, or AI, is suddenly everywhere. From ChatGPT to automated customer service "representatives,” the ability of computers to perform increasingly complicate