Vitamin C may hold the key to improve efficacy of dendritic cell-derived anticancer cell therapies

byJosep Carreras Leukaemia Research InstituteVitamin C-mediated dendritic cell DNA methylome remodeling. (A) Scheme depicting the experimental setup. Monocytes (MO) were differentiated to dendri

Updated on: January 08,2024 9

Vitamin C may hold the key to improve efficacy of dendritic cell-derived anticancer cell therapies

byJosep Carreras Leukaemia Research InstituteVitamin C-mediated dendritic cell DNA methylome remodeling. (A) Scheme depicting the experimental setup. Monocytes (MO) were differentiated to dendri

Updated on:January 08,2024 9

Taking a closer look at eye cancer: Research offers new insight into high rate of metastasis

byEdith Cowan UniversityCredit: Marc Schulte from PexelsNew research from Edith Cowan University (ECU) is one step closer to understanding why uveal melanoma, the deadliest form of eye cancer, h

Updated on: August 01,2024 0

Taking a closer look at eye cancer: Research offers new insight into high rate of metastasis

byEdith Cowan UniversityCredit: Marc Schulte from PexelsNew research from Edith Cowan University (ECU) is one step closer to understanding why uveal melanoma, the deadliest form of eye cancer, h

Updated on:August 01,2024 0

How the environment is silently shaping cancer risk: Data helps untangle links between pollution and cancer

by Niyati Jain,University of ChicagoDifferential expression of gene pathways in BCC (in blue) compared to healthy skin tissue (in red) by PTCH1 mutational status. BCC tissues with no non-synonym

Updated on: December 01,2024 0

How the environment is silently shaping cancer risk: Data helps untangle links between pollution and cancer

by Niyati Jain,University of ChicagoDifferential expression of gene pathways in BCC (in blue) compared to healthy skin tissue (in red) by PTCH1 mutational status. BCC tissues with no non-synonym

Updated on:December 01,2024 0

12.8 percent of unique prescribers prescribed topical antifungals in 2021

by Elana GotkineIn 2021, 12.8 percent of unique prescribers in Medicare Part D prescribed topical antifungals, with about 6.5 million topical antifungal prescriptions filled, at a total cost of $231 m

Updated on: March 22,2024 17

12.8 percent of unique prescribers prescribed topical antifungals in 2021

by Elana GotkineIn 2021, 12.8 percent of unique prescribers in Medicare Part D prescribed topical antifungals, with about 6.5 million topical antifungal prescriptions filled, at a total cost of $231 m

Updated on:March 22,2024 17

Bloomberg School Researchers Develop Universal Risk Predictor for Cardiovascular Disease

Universal risk predictor for cardiovascular disease, suitable for use in both primary and secondary prevention, would streamline risk assessmentPublishedJanuary 29, 2024EPIDEMIOLOGYResearchers from th

Updated on: February 18,2024 15

Bloomberg School Researchers Develop Universal Risk Predictor for Cardiovascular Disease

Universal risk predictor for cardiovascular disease, suitable for use in both primary and secondary prevention, would streamline risk assessmentPublishedJanuary 29, 2024EPIDEMIOLOGYResearchers from th

Updated on:February 18,2024 15

Study: Key mechanisms of action differences in immune checkpoint inhibitor combination therapies for advanced melanoma

byH. Lee Moffitt Cancer Center & Research InstituteProposed mechanism of the two ICI combinations. Graphic created with Biorender (biorender.com). ICI, immune checkpoint inhibitor. Credit:&n

Updated on: January 25,2024 20

Study: Key mechanisms of action differences in immune checkpoint inhibitor combination therapies for advanced melanoma

byH. Lee Moffitt Cancer Center & Research InstituteProposed mechanism of the two ICI combinations. Graphic created with Biorender (biorender.com). ICI, immune checkpoint inhibitor. Credit:&n

Updated on:January 25,2024 20

Study identifies link between DNA-protein binding, cancer onset

byStanford University Medical CenterResearchers at the Stanford University School of Medicine and their collaborators at other institutions have identified a link between how proteins bind to ou

Updated on: December 18,2023 22

Study identifies link between DNA-protein binding, cancer onset

byStanford University Medical CenterResearchers at the Stanford University School of Medicine and their collaborators at other institutions have identified a link between how proteins bind to ou

Updated on:December 18,2023 22

A treatment for metastasis? Using ferroptosis to attack migrating cancer cells

byFriedrich–Alexander University Erlangen–NurnbergZeb1 regulates the expression of enzymes crucial for adjusting the PUFA:MUFA ratio in phospholipids. Credit:Nature Cell Biology(2024

Updated on: July 17,2024 0

A treatment for metastasis? Using ferroptosis to attack migrating cancer cells

byFriedrich–Alexander University Erlangen–NurnbergZeb1 regulates the expression of enzymes crucial for adjusting the PUFA:MUFA ratio in phospholipids. Credit:Nature Cell Biology(2024

Updated on:July 17,2024 0

For cancer, a biopharmaceutical company and UC San Diego test another kind of immune cell

by Bradley J. Fikes, The San Diego Union-TribuneWhen the U.S. Food and Drug Administration approved the first cell-based gene therapies for cancer in 2017, advanced malignancies once seen as terminal

Updated on: December 18,2023 23

For cancer, a biopharmaceutical company and UC San Diego test another kind of immune cell

by Bradley J. Fikes, The San Diego Union-TribuneWhen the U.S. Food and Drug Administration approved the first cell-based gene therapies for cancer in 2017, advanced malignancies once seen as terminal

Updated on:December 18,2023 23

A HER2-targeting peptide drug conjugate with better penetrability for effective breast cancer therapy

by Compuscript LtdSchematic diagram and pharmacokinetics of HER2-TP-cy5.5 and HER-TA-cy5.5 conjugate synthesis. (A) Schematic representation of the utilization of HER2-targeting peptide/antibody and C

Updated on: February 01,2024 10

A HER2-targeting peptide drug conjugate with better penetrability for effective breast cancer therapy

by Compuscript LtdSchematic diagram and pharmacokinetics of HER2-TP-cy5.5 and HER-TA-cy5.5 conjugate synthesis. (A) Schematic representation of the utilization of HER2-targeting peptide/antibody and C

Updated on:February 01,2024 10

Supercharging CAR-T cells for cancer treatment

byEcole Polytechnique Federale de LausanneIL-10-expressing CAR T cells counter dysfunction in tumors.a, Schematic depicting the HER2 CAR and IL-10 HER2 CAR constructs; scFv, single-chain v

Updated on: January 26,2024 16

Supercharging CAR-T cells for cancer treatment

byEcole Polytechnique Federale de LausanneIL-10-expressing CAR T cells counter dysfunction in tumors.a, Schematic depicting the HER2 CAR and IL-10 HER2 CAR constructs; scFv, single-chain v

Updated on:January 26,2024 16

Boosting the cancer-destroying ability of killer T-cells

by Julia Short,Cardiff UniversityCredit: CC0 Public DomainMore types of cancer could potentially be destroyed by patients' own immune cells, thanks to new research by Cardiff University.The

Updated on: April 18,2024 13

Boosting the cancer-destroying ability of killer T-cells

by Julia Short,Cardiff UniversityCredit: CC0 Public DomainMore types of cancer could potentially be destroyed by patients' own immune cells, thanks to new research by Cardiff University.The

Updated on:April 18,2024 13