Clinical trial generates promising results for immunotherapy drug nivolumab in patients with advanced skin cancer

byWileyCredit: CC0 Public DomainNumerous studies have shown that drugs called immune checkpoint inhibitors can boost the immune system's response against various cancers. Now a phase II clin

Updated on: January 02,2024 9

Clinical trial generates promising results for immunotherapy drug nivolumab in patients with advanced skin cancer

byWileyCredit: CC0 Public DomainNumerous studies have shown that drugs called immune checkpoint inhibitors can boost the immune system's response against various cancers. Now a phase II clin

Updated on:January 02,2024 9

Ibrutinib and venetoclax combo effective as front-line therapy for select chronic lymphocytic leukemia patients

by University of Texas M. D. Anderson Cancer CenterA Wright's stained bone marrow aspirate smear of patient with precursor B-cell acute lymphoblastic leukemia. Credit: VashiDonsk/Wikimedia/CC

Updated on: May 17,2024 3

Ibrutinib and venetoclax combo effective as front-line therapy for select chronic lymphocytic leukemia patients

by University of Texas M. D. Anderson Cancer CenterA Wright's stained bone marrow aspirate smear of patient with precursor B-cell acute lymphoblastic leukemia. Credit: VashiDonsk/Wikimedia/CC

Updated on:May 17,2024 3

Targeted therapy better for repeat kidney cancer patients than FDA-approved counterpart

by City of HopeKiller T cells surround a cancer cell. Credit: NIHKidney cancer patients who had already tried two or three different treatments had improved chances of preventing cancer progression wi

Updated on: April 14,2024 20

Targeted therapy better for repeat kidney cancer patients than FDA-approved counterpart

by City of HopeKiller T cells surround a cancer cell. Credit: NIHKidney cancer patients who had already tried two or three different treatments had improved chances of preventing cancer progression wi

Updated on:April 14,2024 20

Solving the mystery of NPM1 in acute myeloid leukemia

by Allison Mickey,Baylor College of MedicineDr. Margaret Goodell, the corresponding author of this work. Credit: Baylor College of MedicineAlthough it has long been recognized that mutations of

Updated on: March 12,2024 14

Solving the mystery of NPM1 in acute myeloid leukemia

by Allison Mickey,Baylor College of MedicineDr. Margaret Goodell, the corresponding author of this work. Credit: Baylor College of MedicineAlthough it has long been recognized that mutations of

Updated on:March 12,2024 14

Alterations in the blood immune system found to increase cancer risk

by Germans Trias i Pujol Research InstitutePleiotropicRNYsare linked to SLE risk and plasmaRNYsare relatively abundant preceding breast cancer diagnosis.aScatter pl

Updated on: April 22,2024 0

Alterations in the blood immune system found to increase cancer risk

by Germans Trias i Pujol Research InstitutePleiotropicRNYsare linked to SLE risk and plasmaRNYsare relatively abundant preceding breast cancer diagnosis.aScatter pl

Updated on:April 22,2024 0

Researchers discover molecule that promotes production of cancer cells in triple-negative breast cancer

byHiroshima UniversityHiroshima University researchers found that AIbZIP is highly upregulated in triple negative breast cancer (TNBC). AIbZIP induces hyper proliferation of TNBC cells by promot

Updated on: March 30,2024 0

Researchers discover molecule that promotes production of cancer cells in triple-negative breast cancer

byHiroshima UniversityHiroshima University researchers found that AIbZIP is highly upregulated in triple negative breast cancer (TNBC). AIbZIP induces hyper proliferation of TNBC cells by promot

Updated on:March 30,2024 0

Researchers identify potential target in myeloid malignancies

by Children's Hospital of PhiladelphiaGraphical abstract. Credit:Journal of Clinical Investigation(2023). DOI: 10.1172/JCI165510Researchers at Children's Hospital of Philadelp

Updated on: February 18,2024 17

Researchers identify potential target in myeloid malignancies

by Children's Hospital of PhiladelphiaGraphical abstract. Credit:Journal of Clinical Investigation(2023). DOI: 10.1172/JCI165510Researchers at Children's Hospital of Philadelp

Updated on:February 18,2024 17

Tumor macrophage marker offers unique target for treatment

by National Institutes of HealthA nanoparticle attached to CRV (CRV-NP) specifically homed to macrophages in breast tumors in mice (yellow arrow) and did not home to spleen, lung or heart. Nanopa

Updated on: April 09,2024 18

Tumor macrophage marker offers unique target for treatment

by National Institutes of HealthA nanoparticle attached to CRV (CRV-NP) specifically homed to macrophages in breast tumors in mice (yellow arrow) and did not home to spleen, lung or heart. Nanopa

Updated on:April 09,2024 18

Blocking key pathways is a way to defeat cancer stem cells

by RIKENCancer cell during cell division. Credit: National Institutes of HealthScientists from the RIKEN Center for Integrative Medical Sciences in Japan and international collaborators have foun

Updated on: April 01,2024 10

Blocking key pathways is a way to defeat cancer stem cells

by RIKENCancer cell during cell division. Credit: National Institutes of HealthScientists from the RIKEN Center for Integrative Medical Sciences in Japan and international collaborators have foun

Updated on:April 01,2024 10

Cellular power-up: Stem cells provide T cells a lifeline as cancer champions

by University of Los AndesExperimental workflow of MitoT to native and CAR engineered T cells. Credit:Journal of Translational Medicine(2024). DOI: 10.1186/s12967-024-05627-4In a pioneerin

Updated on: October 24,2024 0

Cellular power-up: Stem cells provide T cells a lifeline as cancer champions

by University of Los AndesExperimental workflow of MitoT to native and CAR engineered T cells. Credit:Journal of Translational Medicine(2024). DOI: 10.1186/s12967-024-05627-4In a pioneerin

Updated on:October 24,2024 0

Researchers publish preclinical data on new drug combination to treat neuroblastoma

by Texas Tech UniversityTTUHSC's C. Patrick Reynolds, M.D., Ph.D., recently published preclinical data on a new drug combination to treat neuroblastoma. Credit: TTUHSCNeuroblastoma is the mos

Updated on: June 15,2024 8

Researchers publish preclinical data on new drug combination to treat neuroblastoma

by Texas Tech UniversityTTUHSC's C. Patrick Reynolds, M.D., Ph.D., recently published preclinical data on a new drug combination to treat neuroblastoma. Credit: TTUHSCNeuroblastoma is the mos

Updated on:June 15,2024 8

Researchers use AI to establish molecular tumor classification and prognosis in patients with colorectal cancer

by University of ZurichThe image-based consensus molecular subtypes (imCMS) model can be used to predict the molecular classification of each individual image region in patient tumor samples. Thi

Updated on: June 08,2024 6

Researchers use AI to establish molecular tumor classification and prognosis in patients with colorectal cancer

by University of ZurichThe image-based consensus molecular subtypes (imCMS) model can be used to predict the molecular classification of each individual image region in patient tumor samples. Thi

Updated on:June 08,2024 6