Researcher: Big data, networks identify cell signaling pathways in lung cancer

by University of MontanaThe cover of the May 22 issue ofScience Signalingfeatures a three-dimensional representation of lung cancer protein modifications produced by the machine learn

Updated on: June 24,2024

Researcher: Big data, networks identify cell signaling pathways in lung cancer

by University of MontanaThe cover of the May 22 issue ofScience Signalingfeatures a three-dimensional representation of lung cancer protein modifications produced by the machine learn

Updated on:June 24,2024

The impact of cohesin mutations: Insights into a hidden regulator of alternative splicing in leukemia

by Justin Jackson , Medical XpressCohesin regulates alternative splicing. (A) Flowchart showing the experimental protocol, as detailed in Materials and Methods. (B) Schematic showing five different cl

Updated on: January 02,2024

The impact of cohesin mutations: Insights into a hidden regulator of alternative splicing in leukemia

by Justin Jackson , Medical XpressCohesin regulates alternative splicing. (A) Flowchart showing the experimental protocol, as detailed in Materials and Methods. (B) Schematic showing five different cl

Updated on:January 02,2024

Loss of Y chromosome in men enables cancer to grow, finds new study

by Cedars-Sinai Medical CenterCredit: Pixabay/CC0 Public DomainAs men age, some of their cells lose the very thing that makes them biological males—the Y chromosome—and this loss hampers the body

Updated on: January 30,2024

Loss of Y chromosome in men enables cancer to grow, finds new study

by Cedars-Sinai Medical CenterCredit: Pixabay/CC0 Public DomainAs men age, some of their cells lose the very thing that makes them biological males—the Y chromosome—and this loss hampers the body

Updated on:January 30,2024

A new blood test could detect early stage melanoma in more than 80% of patients

by Mel Ziman,The ConversationCredit: AI-generated imageMelanoma killsmore than 1,700 Australians every year, which is more than thenational road toll. But the good news is it's t

Updated on: May 21,2024

A new blood test could detect early stage melanoma in more than 80% of patients

by Mel Ziman,The ConversationCredit: AI-generated imageMelanoma killsmore than 1,700 Australians every year, which is more than thenational road toll. But the good news is it's t

Updated on:May 21,2024

A potential therapeutic vaccine strategy for a subset of myeloproliferative neoplasms

by Ludwig Cancer ResearchCredit: CC0 Public DomainThe cells of a subset of myeloproliferative neoplasms (MPNs), slow-growing blood cancers, have frameshift mutations in their calreticulin (CALR)

Updated on: January 29,2024

A potential therapeutic vaccine strategy for a subset of myeloproliferative neoplasms

by Ludwig Cancer ResearchCredit: CC0 Public DomainThe cells of a subset of myeloproliferative neoplasms (MPNs), slow-growing blood cancers, have frameshift mutations in their calreticulin (CALR)

Updated on:January 29,2024

Killing pancreatic cancer with T cells that supercharge themselves

by University of California, San FranciscoTherapeutic T cells engineered with tumor-triggered IL-2 production infiltrate and clear immune-excluded tumors. (A) We hypothesized that cell autonomous

Updated on: February 18,2024

Killing pancreatic cancer with T cells that supercharge themselves

by University of California, San FranciscoTherapeutic T cells engineered with tumor-triggered IL-2 production infiltrate and clear immune-excluded tumors. (A) We hypothesized that cell autonomous

Updated on:February 18,2024

Investigators build a better targeted drug therapy using the power of computation

by Brigham and Women's HospitalCancer cell during cell division. Credit: National Institutes of HealthAntibody drug conjugates (ADCs)—cancer drugs that are designed to target and destroy canc

Updated on: June 08,2024

Investigators build a better targeted drug therapy using the power of computation

by Brigham and Women's HospitalCancer cell during cell division. Credit: National Institutes of HealthAntibody drug conjugates (ADCs)—cancer drugs that are designed to target and destroy canc

Updated on:June 08,2024

ASCO: Pembrolizumab superior for initial Tx of advanced NSCLC

(HealthDay)—For patients with programmed death ligand 1 (PD-L1)-expressing locally advanced or metastatic non-small-cell lung cancer (NSCLC), pembrolizumab is associated with better overall survival t

Updated on: March 30,2024

ASCO: Pembrolizumab superior for initial Tx of advanced NSCLC

(HealthDay)—For patients with programmed death ligand 1 (PD-L1)-expressing locally advanced or metastatic non-small-cell lung cancer (NSCLC), pembrolizumab is associated with better overall survival t

Updated on:March 30,2024

Novel allogeneic CAR T cell therapy shows promising results in patients with metastatic clear cell renal cell carcinoma

byUniversity of Texas M. D. Anderson Cancer CenterCredit: Pixabay/CC0 Public DomainThe CD70-targeting allogeneic chimeric antigen receptor (CAR) T cell therapy, ALLO-316, demonstrated encouragin

Updated on: January 15,2024

Novel allogeneic CAR T cell therapy shows promising results in patients with metastatic clear cell renal cell carcinoma

byUniversity of Texas M. D. Anderson Cancer CenterCredit: Pixabay/CC0 Public DomainThe CD70-targeting allogeneic chimeric antigen receptor (CAR) T cell therapy, ALLO-316, demonstrated encouragin

Updated on:January 15,2024

Researchers show potential liver cancer treatment by targeting cancer stem-like cells

by National University of SingaporeLiver cancer stem-like cells grown as tumourspheres that are sensitive to JAK/STAT small molecule inhibitors. Credit: National University of SingaporeLiver canc

Updated on: March 01,2024

Researchers show potential liver cancer treatment by targeting cancer stem-like cells

by National University of SingaporeLiver cancer stem-like cells grown as tumourspheres that are sensitive to JAK/STAT small molecule inhibitors. Credit: National University of SingaporeLiver canc

Updated on:March 01,2024

Major breakthrough in quest for cancer vaccine

by University of MontrealCredit: CC0 Public DomainThe idea of a cancer vaccine is something researchers have been working on for over 50 years, but until recently they were never able to prove ex

Updated on: March 06,2024

Major breakthrough in quest for cancer vaccine

by University of MontrealCredit: CC0 Public DomainThe idea of a cancer vaccine is something researchers have been working on for over 50 years, but until recently they were never able to prove ex

Updated on:March 06,2024

New marker could detect fatal breast cancer up to one year earlier than current methods

by BioMed CentralMammograms showing a normal breast (left) and a breast with cancer (right). Credit: Public DomainA new marker that could be used to diagnose fatal breast cancer up to one year ah

Updated on: March 01,2024

New marker could detect fatal breast cancer up to one year earlier than current methods

by BioMed CentralMammograms showing a normal breast (left) and a breast with cancer (right). Credit: Public DomainA new marker that could be used to diagnose fatal breast cancer up to one year ah

Updated on:March 01,2024