Scientists develop a peptide that targets lung tumors and delivers therapeutics inside cells

bySRI InternationalMonomeric and tetrameric MGS4 have similar binding, internalization and subcellular location. a, Binding and internalization of tetrameric MGS4_V1 and monomeric MGS4_V2 on liv

Updated on: December 27,2023 10

Scientists develop a peptide that targets lung tumors and delivers therapeutics inside cells

bySRI InternationalMonomeric and tetrameric MGS4 have similar binding, internalization and subcellular location. a, Binding and internalization of tetrameric MGS4_V1 and monomeric MGS4_V2 on liv

Updated on:December 27,2023 10

New model identifies drugs that shouldn't be taken together

by Massachusetts Institute of TechnologyCredit: CC0 Public DomainAny drug that is taken orally must pass through the lining of the digestive tract. Transporter proteins found on cells that line t

Updated on: March 21,2024 13

New model identifies drugs that shouldn't be taken together

by Massachusetts Institute of TechnologyCredit: CC0 Public DomainAny drug that is taken orally must pass through the lining of the digestive tract. Transporter proteins found on cells that line t

Updated on:March 21,2024 13

The architectural role of p53: Early 3D chromatin remodeling to trigger cellular stress response

byJosep Carreras Leukaemia Research InstituteTAD dynamics along p53 activation. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-46666-1The simplest explanation of cancer

Updated on: April 28,2024 0

The architectural role of p53: Early 3D chromatin remodeling to trigger cellular stress response

byJosep Carreras Leukaemia Research InstituteTAD dynamics along p53 activation. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-46666-1The simplest explanation of cancer

Updated on:April 28,2024 0

Breakaway breast cancer cells can travel to the brain: Scientists plot path in quest to block entry

by Delthia Ricks , Medical XpressIn vitro characterization of in vivo / ex vivo-derived 4T1 metastatic cell lines. (A) Schematic representation of the procedure used to generate the 4T1-BM2 metastatic

Updated on: December 22,2023 9

Breakaway breast cancer cells can travel to the brain: Scientists plot path in quest to block entry

by Delthia Ricks , Medical XpressIn vitro characterization of in vivo / ex vivo-derived 4T1 metastatic cell lines. (A) Schematic representation of the procedure used to generate the 4T1-BM2 metastatic

Updated on:December 22,2023 9

Researchers design new hydrogel for more targeted cancer treatments

by Safa Jinje,University of TorontoGraphical abstract. Credit:Materials Today(2022). DOI: 10.1016/j.mattod.2022.01.023University of Toronto researchers have designed a new way to gro

Updated on: December 22,2023 22

Researchers design new hydrogel for more targeted cancer treatments

by Safa Jinje,University of TorontoGraphical abstract. Credit:Materials Today(2022). DOI: 10.1016/j.mattod.2022.01.023University of Toronto researchers have designed a new way to gro

Updated on:December 22,2023 22

Breast cancer patients to be evaluated for genetic testing

byVanderbilt University Medical CenterCredit: CC0 Public DomainAccording to a statement on behalf of the American College of Medical Genetics and Genomics (ACMG) published Dec. 13 in the organiz

Updated on: December 22,2023 24

Breast cancer patients to be evaluated for genetic testing

byVanderbilt University Medical CenterCredit: CC0 Public DomainAccording to a statement on behalf of the American College of Medical Genetics and Genomics (ACMG) published Dec. 13 in the organiz

Updated on:December 22,2023 24

For first time in 40 years, cure for acute leukemia within reach

by Tali Aronsky,Hebrew University of JerusalemBone marrow aspirate showing acute myeloid leukemia. Several blasts have Auer rods. Credit: WikipediaAcute myeloid leukemia is one of the most aggre

Updated on: March 14,2024 14

For first time in 40 years, cure for acute leukemia within reach

by Tali Aronsky,Hebrew University of JerusalemBone marrow aspirate showing acute myeloid leukemia. Several blasts have Auer rods. Credit: WikipediaAcute myeloid leukemia is one of the most aggre

Updated on:March 14,2024 14

Obesity is a risk factor for cardiotoxicity in chemotherapy-treated patients with breast cancer

byPublic Library of ScienceObesity is associated with a three-fold increased risk of cardiotoxicity in chemotherapy-treated patients with early-stage breast cancer, regardless of other predictor

Updated on: December 22,2023 17

Obesity is a risk factor for cardiotoxicity in chemotherapy-treated patients with breast cancer

byPublic Library of ScienceObesity is associated with a three-fold increased risk of cardiotoxicity in chemotherapy-treated patients with early-stage breast cancer, regardless of other predictor

Updated on:December 22,2023 17

Breast cancer risk from menopause hormones may last decades

by Marilynn MarchioneIn this May 6, 2010 file photo, a radiologist checks mammograms in in Los Angeles. Women who use certain types of hormones after menopause still have an increased risk of developi

Updated on: December 22,2023 12

Breast cancer risk from menopause hormones may last decades

by Marilynn MarchioneIn this May 6, 2010 file photo, a radiologist checks mammograms in in Los Angeles. Women who use certain types of hormones after menopause still have an increased risk of developi

Updated on:December 22,2023 12

Non-hormonal therapy reduces hot flashes and night sweats in women who have been diagnosed with breast cancer

by Cheryl Critchley,Monash UniversityCredit: Pixabay/CC0 Public DomainA Monash University-led trial of a new drug known as Q-122 therapy significantly reduced the number and severity of hot flas

Updated on: December 22,2023 10

Non-hormonal therapy reduces hot flashes and night sweats in women who have been diagnosed with breast cancer

by Cheryl Critchley,Monash UniversityCredit: Pixabay/CC0 Public DomainA Monash University-led trial of a new drug known as Q-122 therapy significantly reduced the number and severity of hot flas

Updated on:December 22,2023 10

Marker found for condition that causes numerous tumors

by Cathy Frisinger,UT Southwestern Medical CenterCutaneous neurofibromas cover the back of a patient. Credit: UTSWUT Southwestern researchers have made a major advance in uncovering the biology

Updated on: December 18,2023 16

Marker found for condition that causes numerous tumors

by Cathy Frisinger,UT Southwestern Medical CenterCutaneous neurofibromas cover the back of a patient. Credit: UTSWUT Southwestern researchers have made a major advance in uncovering the biology

Updated on:December 18,2023 16

Olaparib maintenance extends PFS by estimated three years in advanced ovarian cancer

byEuropean Society for Medical OncologyTwo-year maintenance therapy with olaparib, a PARP (poly ADP ribose polymerase) inhibitor, olaparib, led to a substantial, unprecedented improvement in pro

Updated on: December 18,2023 13

Olaparib maintenance extends PFS by estimated three years in advanced ovarian cancer

byEuropean Society for Medical OncologyTwo-year maintenance therapy with olaparib, a PARP (poly ADP ribose polymerase) inhibitor, olaparib, led to a substantial, unprecedented improvement in pro

Updated on:December 18,2023 13