Novel combination therapy has similar response rates to chemotherapy for high-risk luminal B breast cancer

byAmerican Association for Cancer ResearchNeoadjuvant treatment with the CDK4/6 inhibitor ribociclib (Kisqali) and the aromatase inhibitor letrozole (Femara) produced response rates similar to m

Updated on: December 22,2023 10

Novel combination therapy has similar response rates to chemotherapy for high-risk luminal B breast cancer

byAmerican Association for Cancer ResearchNeoadjuvant treatment with the CDK4/6 inhibitor ribociclib (Kisqali) and the aromatase inhibitor letrozole (Femara) produced response rates similar to m

Updated on:December 22,2023 10

Finding familiar pathways in kidney cancer

byThomas Jefferson UniversityCredit: CC0 Public Domainp53 is the most famous cancer gene, not least because it's involved in causing over 50% of all cancers. When a cell loses its p53 gene—w

Updated on: December 22,2023 20

Finding familiar pathways in kidney cancer

byThomas Jefferson UniversityCredit: CC0 Public Domainp53 is the most famous cancer gene, not least because it's involved in causing over 50% of all cancers. When a cell loses its p53 gene—w

Updated on:December 22,2023 20

Scientists identify the mechanisms leading to resistance to lung cancer treatment with Sotorasib

byThe Spanish National Cancer Research CentreSotorasib-resistant lung cancer cells displaying multiple copies of the mutated KRAS gene (in red) / CICANCER. Credit: CICANCERAccording to recent fi

Updated on: December 27,2023 10

Scientists identify the mechanisms leading to resistance to lung cancer treatment with Sotorasib

byThe Spanish National Cancer Research CentreSotorasib-resistant lung cancer cells displaying multiple copies of the mutated KRAS gene (in red) / CICANCER. Credit: CICANCERAccording to recent fi

Updated on:December 27,2023 10

Resiliency, family support help Hispanic breast cancer survivors manage lymphedema

byUniversity of MissouriCredit: Unsplash/CC0 Public DomainAs a cancer nurse in the U.S. Army for more than 29 years, Elizabeth Anderson saw firsthand how chemotherapy, radiation and surgeries im

Updated on: December 20,2023 10

Resiliency, family support help Hispanic breast cancer survivors manage lymphedema

byUniversity of MissouriCredit: Unsplash/CC0 Public DomainAs a cancer nurse in the U.S. Army for more than 29 years, Elizabeth Anderson saw firsthand how chemotherapy, radiation and surgeries im

Updated on:December 20,2023 10

A new role for a triple-negative breast cancer target

by Katherine Unger Baillie,University of PennsylvaniaLed by Penn Vet scientists, a new study reveals that the protein deltaNp63, whichfosters the initiation and progression of triple-negat

Updated on: December 22,2023 14

A new role for a triple-negative breast cancer target

by Katherine Unger Baillie,University of PennsylvaniaLed by Penn Vet scientists, a new study reveals that the protein deltaNp63, whichfosters the initiation and progression of triple-negat

Updated on:December 22,2023 14

Surgery may add months or years of survival for adults with rare and deadly brain cancers

by Amy Mone,Johns Hopkins UniversityCredit: Alicia Ortega, MSFor adult patients with brainstem high-grade gliomas—one of the rarest and deadliest forms of brain cancer—surgically removing the en

Updated on: December 20,2023 24

Surgery may add months or years of survival for adults with rare and deadly brain cancers

by Amy Mone,Johns Hopkins UniversityCredit: Alicia Ortega, MSFor adult patients with brainstem high-grade gliomas—one of the rarest and deadliest forms of brain cancer—surgically removing the en

Updated on:December 20,2023 24

Concentration of surgical care to one research hospital shown to improve operations for childhood cancer

by Princess Máxima Center for Pediatric OncologyEstimated event-free survival (EFS) for neuroblastoma provided by Kaplan Meier's methodology (log rank 0.260). Credit: European Journal of Surgical

Updated on: December 26,2023 9

Concentration of surgical care to one research hospital shown to improve operations for childhood cancer

by Princess Máxima Center for Pediatric OncologyEstimated event-free survival (EFS) for neuroblastoma provided by Kaplan Meier's methodology (log rank 0.260). Credit: European Journal of Surgical

Updated on:December 26,2023 9

When combined, a novel LSD1 inhibitor and an existing therapy enhance each other's anti-cancer effects

by Jaclyn Dunne,Medical University of South CarolinaGraphical abstract. Credit:European Journal of Medicinal Chemistry(2022). DOI: 10.1016/j.ejmech.2022.114818A Medical University of

Updated on: December 20,2023 10

When combined, a novel LSD1 inhibitor and an existing therapy enhance each other's anti-cancer effects

by Jaclyn Dunne,Medical University of South CarolinaGraphical abstract. Credit:European Journal of Medicinal Chemistry(2022). DOI: 10.1016/j.ejmech.2022.114818A Medical University of

Updated on:December 20,2023 10

Research reveals pro-phagocytic function and structural basis of GPR84 signaling

by University of Science and Technology of ChinaGPR84-Gi signaling facilitates cancer cell phagocytosis. Credit:Nature Communications(2023). DOI: 10.1038/s41467-023-41201-0A recent study,

Updated on: January 28,2024 12

Research reveals pro-phagocytic function and structural basis of GPR84 signaling

by University of Science and Technology of ChinaGPR84-Gi signaling facilitates cancer cell phagocytosis. Credit:Nature Communications(2023). DOI: 10.1038/s41467-023-41201-0A recent study,

Updated on:January 28,2024 12

Longer wait for some forms of cancer diagnosis for Black and Asian patients

byUniversity of ExeterSite-specific box and Whisker plots showing ethnic differences in the number of days to diagnosis (lower adjacent value, 25th, 50th, and 75th centiles, and upper adjacent v

Updated on: December 24,2023 12

Longer wait for some forms of cancer diagnosis for Black and Asian patients

byUniversity of ExeterSite-specific box and Whisker plots showing ethnic differences in the number of days to diagnosis (lower adjacent value, 25th, 50th, and 75th centiles, and upper adjacent v

Updated on:December 24,2023 12

Organ transplant does not worsen prostate cancer outcome

(HealthDay)—Among older men with prostate cancer, an organ transplant is associated with higher overall mortality, but not prostate cancer-specific mortality (PCSM), according to a study published onl

Updated on: December 22,2023 12

Organ transplant does not worsen prostate cancer outcome

(HealthDay)—Among older men with prostate cancer, an organ transplant is associated with higher overall mortality, but not prostate cancer-specific mortality (PCSM), according to a study published onl

Updated on:December 22,2023 12

Head and neck cancer survivors at increased risk of suicide

by Maggie Rotermund,Saint Louis UniversityNosayaba Osazuwa-Peters, BDS, PH.D., MPH, is an assistant professor of otolaryngology at Saint Louis University School of Medicine and faculty member at

Updated on: December 18,2023 23

Head and neck cancer survivors at increased risk of suicide

by Maggie Rotermund,Saint Louis UniversityNosayaba Osazuwa-Peters, BDS, PH.D., MPH, is an assistant professor of otolaryngology at Saint Louis University School of Medicine and faculty member at

Updated on:December 18,2023 23