How cancer cells die: Scientists explore new pathways of pyroptosis, killer kin of apoptosis

by Delthia Ricks , Medical XpressLymphoid BLaER1 cells undergo PANX1-dominant lysis. (A to C) BLaER1 cells were treated with topoisomerase poisons doxorubicin (2 μM) or etoposide (50 μM) for 24 hours.

Updated on: December 18,2023 8

How cancer cells die: Scientists explore new pathways of pyroptosis, killer kin of apoptosis

by Delthia Ricks , Medical XpressLymphoid BLaER1 cells undergo PANX1-dominant lysis. (A to C) BLaER1 cells were treated with topoisomerase poisons doxorubicin (2 μM) or etoposide (50 μM) for 24 hours.

Updated on:December 18,2023 8

Scientists describe how iron helps drive tumor development in colorectal cancer

by Michael Haederle,University of New MexicoTFRC is increased in human CRC and is positively correlated with the CTNNB1 protein expression. Detection of TFRC expression in human normal (n = 5–8)

Updated on: December 27,2023 10

Scientists describe how iron helps drive tumor development in colorectal cancer

by Michael Haederle,University of New MexicoTFRC is increased in human CRC and is positively correlated with the CTNNB1 protein expression. Detection of TFRC expression in human normal (n = 5–8)

Updated on:December 27,2023 10

Timing androgen-deprivation therapy with radiation therapy improves outcomes in localized prostate cancer

byUniversity of California, Los AngelesUnadjusted Kaplan-Meier and cumulative incidence curves evaluating the associations between concurrent/adjuvant versus neoadjuvant/concurrent ADT sequencin

Updated on: December 20,2023 12

Timing androgen-deprivation therapy with radiation therapy improves outcomes in localized prostate cancer

byUniversity of California, Los AngelesUnadjusted Kaplan-Meier and cumulative incidence curves evaluating the associations between concurrent/adjuvant versus neoadjuvant/concurrent ADT sequencin

Updated on:December 20,2023 12

Childhood cancer deaths in the United States have declined six-fold over the last seventy years

Childhood cancer deaths in the United States have fallen dramatically over time, as shown in the chart. It presents annual cancer death rates in children under five years old.

Updated on: January 15,2025 0

Childhood cancer deaths in the United States have declined six-fold over the last seventy years

Childhood cancer deaths in the United States have fallen dramatically over time, as shown in the chart. It presents annual cancer death rates in children under five years old.

Updated on:January 15,2025 0

Looking at the role epigenetics plays in the ways cancer behaves

by Bob Yirka , Medical XpressGenetic control of expression with eQTL. a, The number of genes with significant models for each data type. b, Distribution of regression coefficients (effect sizes) for e

Updated on: December 27,2023 12

Looking at the role epigenetics plays in the ways cancer behaves

by Bob Yirka , Medical XpressGenetic control of expression with eQTL. a, The number of genes with significant models for each data type. b, Distribution of regression coefficients (effect sizes) for e

Updated on:December 27,2023 12

Researchers identify immune-suppressing target in glioblastoma

byUniversity of Texas M. D. Anderson Cancer CenterGlioblastoma (histology slide). Credit: Wikipedia/CC BY-SA 3.0Researchers at The University of Texas MD Anderson Cancer Center have identified a

Updated on: December 23,2023 15

Researchers identify immune-suppressing target in glioblastoma

byUniversity of Texas M. D. Anderson Cancer CenterGlioblastoma (histology slide). Credit: Wikipedia/CC BY-SA 3.0Researchers at The University of Texas MD Anderson Cancer Center have identified a

Updated on:December 23,2023 15

New imaging system and artificial intelligence algorithm accurately identify brain tumors

byNYU Langone HealthStimulated Raman histologic images of diffuse astrocytoma (left) and meningioma (right). Credit: Daniel Orringer, NYU Langone HealthA novel method of combining advanced optic

Updated on: December 22,2023 11

New imaging system and artificial intelligence algorithm accurately identify brain tumors

byNYU Langone HealthStimulated Raman histologic images of diffuse astrocytoma (left) and meningioma (right). Credit: Daniel Orringer, NYU Langone HealthA novel method of combining advanced optic

Updated on:December 22,2023 11

New study suggests 21-gene recurrence score may help in radiation decision-making

by SWOGA new study shows that a test physicians commonly used to guide chemotherapy treatment for post-breast cancer surgery patients may also help them decide whether radiation therapy may be of bene

Updated on: December 20,2023 24

New study suggests 21-gene recurrence score may help in radiation decision-making

by SWOGA new study shows that a test physicians commonly used to guide chemotherapy treatment for post-breast cancer surgery patients may also help them decide whether radiation therapy may be of bene

Updated on:December 20,2023 24

Novel genetic signature that can predict some kinds of breast cancer is identified

by Maria Fernanda Ziegler,FAPESPBlood vessels from the retina of a mouse with retinopathy, normal and pathological vessels stained green and red respectively. Credit: Ricardo GiordanoResearchers

Updated on: December 22,2023 12

Novel genetic signature that can predict some kinds of breast cancer is identified

by Maria Fernanda Ziegler,FAPESPBlood vessels from the retina of a mouse with retinopathy, normal and pathological vessels stained green and red respectively. Credit: Ricardo GiordanoResearchers

Updated on:December 22,2023 12

Local radiotherapy improves survival in metastatic prostate cancer with low disease burden

byEuropean Society for Medical OncologyRadiotherapy to the prostate improves overall survival in men newly diagnosed with metastatic prostate cancer who have a low metastatic disease burden but

Updated on: December 18,2023 13

Local radiotherapy improves survival in metastatic prostate cancer with low disease burden

byEuropean Society for Medical OncologyRadiotherapy to the prostate improves overall survival in men newly diagnosed with metastatic prostate cancer who have a low metastatic disease burden but

Updated on:December 18,2023 13

Combination drug therapy shows promise for a treatment-resistant cancer

by Johns Hopkins University School of MedicineChristine Pratilas, M.D., in the lab. Credit: Frederick W. Dubs, Johns Hopkins Pathology Photography & GraphicsA combination of two cancer drugs

Updated on: May 21,2024 4

Combination drug therapy shows promise for a treatment-resistant cancer

by Johns Hopkins University School of MedicineChristine Pratilas, M.D., in the lab. Credit: Frederick W. Dubs, Johns Hopkins Pathology Photography & GraphicsA combination of two cancer drugs

Updated on:May 21,2024 4

CRISPR-Cas9 datasets analysis leads to largest genetic screen resource for cancer research

byWellcome Trust Sanger InstituteCredit: CC0 Public DomainA comprehensive map of genes necessary for cancer survival is one step closer, following the validation of the two largest CRISPR-Cas9 g

Updated on: December 22,2023 12

CRISPR-Cas9 datasets analysis leads to largest genetic screen resource for cancer research

byWellcome Trust Sanger InstituteCredit: CC0 Public DomainA comprehensive map of genes necessary for cancer survival is one step closer, following the validation of the two largest CRISPR-Cas9 g

Updated on:December 22,2023 12