Extracellular cell matrix stiffness may induce drug resistance of breast cancer cells

by Shanghai Jiao Tong University Journal CenterCredit:Mechanobiology in Medicine(2023). DOI: 10.1016/j.mbm.2023.100023A new study, led by Prof. Liu from the department of pharmacy, Univers

Updated on: April 30,2024

Extracellular cell matrix stiffness may induce drug resistance of breast cancer cells

by Shanghai Jiao Tong University Journal CenterCredit:Mechanobiology in Medicine(2023). DOI: 10.1016/j.mbm.2023.100023A new study, led by Prof. Liu from the department of pharmacy, Univers

Updated on:April 30,2024

Researchers image live drug response and resistant 'pockets' in pancreatic cancer

by Garvan Institute of Medical ResearchSchematic of spatiotemporal AKT activity mapping in several organ systems in vivo.Optical window–mediated intravital assessment of metabolic and malignancy-

Updated on: February 18,2024

Researchers image live drug response and resistant 'pockets' in pancreatic cancer

by Garvan Institute of Medical ResearchSchematic of spatiotemporal AKT activity mapping in several organ systems in vivo.Optical window–mediated intravital assessment of metabolic and malignancy-

Updated on:February 18,2024

How communication in the tumor microenvironment influences tumor development

by Goethe UniversityTissue section of a lung tumor showing different cells in the tumor microenvironment: macrophages (red), collagen-producing macrophages or fibrocytes (yellow), fibroblasts (green).

Updated on: January 23,2024

How communication in the tumor microenvironment influences tumor development

by Goethe UniversityTissue section of a lung tumor showing different cells in the tumor microenvironment: macrophages (red), collagen-producing macrophages or fibrocytes (yellow), fibroblasts (green).

Updated on:January 23,2024

Metabolic reprogramming of tumor-associated macrophages

by Cactus CommunicationsThe article discusses the metabolic pathways involved in reprograming tumor-associated macrophages, immune cells which contribute to tumor growth. Credit: Yi Zhang from Zhengzh

Updated on: January 22,2024

Metabolic reprogramming of tumor-associated macrophages

by Cactus CommunicationsThe article discusses the metabolic pathways involved in reprograming tumor-associated macrophages, immune cells which contribute to tumor growth. Credit: Yi Zhang from Zhengzh

Updated on:January 22,2024

Peripheral surrogates of tumor burden to guide therapeutic strategies for HPV-associated malignancies

by Impact Journals LLCTumor intrinsic and extrinsic factors in the periphery that can serve as proxies of tumor burden. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28487A new review

Updated on: January 22,2024

Peripheral surrogates of tumor burden to guide therapeutic strategies for HPV-associated malignancies

by Impact Journals LLCTumor intrinsic and extrinsic factors in the periphery that can serve as proxies of tumor burden. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28487A new review

Updated on:January 22,2024

Repurposing heart drugs to target cancer cells

by MRC London Institute of Medical SciencesCredit: CC0 Public DomainSenescence is a cellular stress response that results in the stable growth arrest of old and damaged cells. The past decade has reve

Updated on: April 07,2024

Repurposing heart drugs to target cancer cells

by MRC London Institute of Medical SciencesCredit: CC0 Public DomainSenescence is a cellular stress response that results in the stable growth arrest of old and damaged cells. The past decade has reve

Updated on:April 07,2024

Ancient viruses could help kill cancers

by The Francis Crick InstituteHeatmap showing expression of melanoma-specific transcripts across a range of cancer types. The three columns with high expression are from melanoma samples. Credit:

Updated on: March 30,2024

Ancient viruses could help kill cancers

by The Francis Crick InstituteHeatmap showing expression of melanoma-specific transcripts across a range of cancer types. The three columns with high expression are from melanoma samples. Credit:

Updated on:March 30,2024

Vaccine boosts response of engineered T cells, may help eradicate solid tumors

by Massachusetts Institute of TechnologyCredit: CC0 Public DomainEngineering T cells to destroy cancer cells has shown success in treating some types of cancer, such as leukemia and lymphoma. How

Updated on: January 30,2024

Vaccine boosts response of engineered T cells, may help eradicate solid tumors

by Massachusetts Institute of TechnologyCredit: CC0 Public DomainEngineering T cells to destroy cancer cells has shown success in treating some types of cancer, such as leukemia and lymphoma. How

Updated on:January 30,2024

Researchers study how altered protein degradation contributes to the development of tumors

by Institute for Research in Biomedicine (IRB Barcelona)To ensure adequate levels of proteins in the cell, a strict quality control system is responsible for tagging the proteins with ubiquitin f

Updated on: March 06,2024

Researchers study how altered protein degradation contributes to the development of tumors

by Institute for Research in Biomedicine (IRB Barcelona)To ensure adequate levels of proteins in the cell, a strict quality control system is responsible for tagging the proteins with ubiquitin f

Updated on:March 06,2024

Study shows checkpoint inhibitor prolongs survival in patients with certain head and neck cancers

by Anne Doerr,Yale UniversityCredit: stock.adobe.comThe checkpoint inhibitor pembrolizumab (Keytruda) increases the survival time of patients with advanced head and neck cancers, according to a

Updated on: May 31,2024

Study shows checkpoint inhibitor prolongs survival in patients with certain head and neck cancers

by Anne Doerr,Yale UniversityCredit: stock.adobe.comThe checkpoint inhibitor pembrolizumab (Keytruda) increases the survival time of patients with advanced head and neck cancers, according to a

Updated on:May 31,2024

Researchers find new cancer gene drivers

by Bill Hathaway,Yale UniversityYale researchers exploring the structure of proteins have found evidence of how some genes drive the progression of cancer. Credit: Yale UniversityScientists have

Updated on: June 19,2024

Researchers find new cancer gene drivers

by Bill Hathaway,Yale UniversityYale researchers exploring the structure of proteins have found evidence of how some genes drive the progression of cancer. Credit: Yale UniversityScientists have

Updated on:June 19,2024

Researchers advance CRISPR technology to replicate human diseases with unprecedented accuracy

by Walter and Eliza Hall Institute of Medical ResearchGeneration and validation of pdCas9a-SAM construct in Eµ-Myc lymphoma cell lines. a Schematic representation of the pdCas9a-SAM lentiviral co

Updated on: February 03,2024

Researchers advance CRISPR technology to replicate human diseases with unprecedented accuracy

by Walter and Eliza Hall Institute of Medical ResearchGeneration and validation of pdCas9a-SAM construct in Eµ-Myc lymphoma cell lines. a Schematic representation of the pdCas9a-SAM lentiviral co

Updated on:February 03,2024