New anti-cancer 'degrader' targets protein essential to infant leukemia

byVan Andel Research InstituteDiscovery of a first-in-class, highly potent VHL-recruiting ENL PROTAC degrader, MS41. Credit:Science Advances(2024). DOI: 10.1126/sciadv.ado1432Scienti

Updated on: September 10,2024 0

New anti-cancer 'degrader' targets protein essential to infant leukemia

byVan Andel Research InstituteDiscovery of a first-in-class, highly potent VHL-recruiting ENL PROTAC degrader, MS41. Credit:Science Advances(2024). DOI: 10.1126/sciadv.ado1432Scienti

Updated on:September 10,2024 0

Cancer patients may face greater risk of shingles

(HealthDay)—Newly diagnosed cancer patients may be at increased risk for the painful skin condition shingles, a new study finds.Experts say development of new vaccines might help prevent shingles in&n

Updated on: March 01,2024 19

Cancer patients may face greater risk of shingles

(HealthDay)—Newly diagnosed cancer patients may be at increased risk for the painful skin condition shingles, a new study finds.Experts say development of new vaccines might help prevent shingles in&n

Updated on:March 01,2024 19

Vaccine boosts response of engineered T cells, may help eradicate solid tumors

by Massachusetts Institute of TechnologyCredit: CC0 Public DomainEngineering T cells to destroy cancer cells has shown success in treating some types of cancer, such as leukemia and lymphoma. How

Updated on: January 30,2024 18

Vaccine boosts response of engineered T cells, may help eradicate solid tumors

by Massachusetts Institute of TechnologyCredit: CC0 Public DomainEngineering T cells to destroy cancer cells has shown success in treating some types of cancer, such as leukemia and lymphoma. How

Updated on:January 30,2024 18

Study finds Black patients wait longer for uterine cancer testing, diagnosis

by Mallory Locklear,Yale UniversityCredit: Unsplash/CC0 Public DomainEarly diagnosis of uterine cancer is known to improve a patient's chances for survival, but previous research has found t

Updated on: February 18,2024 10

Study finds Black patients wait longer for uterine cancer testing, diagnosis

by Mallory Locklear,Yale UniversityCredit: Unsplash/CC0 Public DomainEarly diagnosis of uterine cancer is known to improve a patient's chances for survival, but previous research has found t

Updated on:February 18,2024 10

Study may explain why once-promising cancer drugs failed

by Duke UniversityInvading cells (green) in the lab wormC. elegans(purple) can change their tactics to get around cancer drugs called MMP inhibitors and trespass into other tissues. T

Updated on: May 21,2024 3

Study may explain why once-promising cancer drugs failed

by Duke UniversityInvading cells (green) in the lab wormC. elegans(purple) can change their tactics to get around cancer drugs called MMP inhibitors and trespass into other tissues. T

Updated on:May 21,2024 3

More aggressive treatment doesn't impact quality of life for metastatic colorectal cancer patients, says new study

by National Comprehensive Cancer NetworkCredit: Unsplash/CC0 Public DomainNewresearchin the October 2023 issue ofJournal of the National Comprehensive Cancer Networkfinds that

Updated on: May 21,2024 3

More aggressive treatment doesn't impact quality of life for metastatic colorectal cancer patients, says new study

by National Comprehensive Cancer NetworkCredit: Unsplash/CC0 Public DomainNewresearchin the October 2023 issue ofJournal of the National Comprehensive Cancer Networkfinds that

Updated on:May 21,2024 3

Opinion: The urgent need to secure the future of the 'post-pandemic child'

by Monash UniversityCredit: Unsplash/CC0 Public DomainIn 2028, it will be eight years since COVID-19 was first detected in Australia. Today's post-pandemic child will be a teenager, facing a

Updated on: May 11,2024 6

Opinion: The urgent need to secure the future of the 'post-pandemic child'

by Monash UniversityCredit: Unsplash/CC0 Public DomainIn 2028, it will be eight years since COVID-19 was first detected in Australia. Today's post-pandemic child will be a teenager, facing a

Updated on:May 11,2024 6

Breast cancer researchers find bacteria imbalance link

by Cleveland ClinicCharis Eng, M.D., Ph.D., chair of the Cleveland Clinic's Genomic Medicine Institute. Credit: Cleveland ClinicResearchers in the United States have uncovered differences in

Updated on: June 15,2024 7

Breast cancer researchers find bacteria imbalance link

by Cleveland ClinicCharis Eng, M.D., Ph.D., chair of the Cleveland Clinic's Genomic Medicine Institute. Credit: Cleveland ClinicResearchers in the United States have uncovered differences in

Updated on:June 15,2024 7

Researchers identify cell signaling pathways controlling melanoma cell metastasis to the brain

by H. Lee Moffitt Cancer Center & Research InstituteHDAC8 increases the establishment of melanoma brain metastases.a–cHDAC8 and EV expressing WM164 cells were introduced into NOD.

Updated on: June 22,2024 3

Researchers identify cell signaling pathways controlling melanoma cell metastasis to the brain

by H. Lee Moffitt Cancer Center & Research InstituteHDAC8 increases the establishment of melanoma brain metastases.a–cHDAC8 and EV expressing WM164 cells were introduced into NOD.

Updated on:June 22,2024 3

Stress-tolerant cells shown to drive tumor initiation in pancreatic cancer

by University of California - San DiegoTumor-initiating cells (blue) produce an extracellular matrix containing fibronectin (pink) which gives them increased stress tolerance, drug resistance and

Updated on: February 23,2024 16

Stress-tolerant cells shown to drive tumor initiation in pancreatic cancer

by University of California - San DiegoTumor-initiating cells (blue) produce an extracellular matrix containing fibronectin (pink) which gives them increased stress tolerance, drug resistance and

Updated on:February 23,2024 16

Growing brain cancer in a dish

by Austrian Academy of SciencesNeoplastic cerebral organoid with GFP-positive tumor regions (green), which demonstrates glioblastoma-like cellularity. Credit: Austrian Academy of SciencesFor the first

Updated on: April 22,2024 12

Growing brain cancer in a dish

by Austrian Academy of SciencesNeoplastic cerebral organoid with GFP-positive tumor regions (green), which demonstrates glioblastoma-like cellularity. Credit: Austrian Academy of SciencesFor the first

Updated on:April 22,2024 12

Allogeneic hematopoietic cell transplant outcomes improved from 2005 to 2019: Study

by Lori SolomonOutcomes of allogeneic hematopoietic cell transplantation (allo-HCT) in patients with acute myeloid leukemia (AML) and second complete remission (CR2) have significantly improved over t

Updated on: February 18,2024 17

Allogeneic hematopoietic cell transplant outcomes improved from 2005 to 2019: Study

by Lori SolomonOutcomes of allogeneic hematopoietic cell transplantation (allo-HCT) in patients with acute myeloid leukemia (AML) and second complete remission (CR2) have significantly improved over t

Updated on:February 18,2024 17