Study reveals how stem cells respond to environmental signals, with implications for IBD and colorectal cancer

byThe Hospital for Sick ChildrenModel for PIEZO mechanosensing of the ISC niche. Credit:Science(2024). DOI: 10.1126/science.adj7615A new study from The Hospital for Sick Children (Si

Updated on: December 10,2024

Study reveals how stem cells respond to environmental signals, with implications for IBD and colorectal cancer

byThe Hospital for Sick ChildrenModel for PIEZO mechanosensing of the ISC niche. Credit:Science(2024). DOI: 10.1126/science.adj7615A new study from The Hospital for Sick Children (Si

Updated on:December 10,2024

Jumping genes for early detection of gastric cancer

by Braulio Valdebenito-MaturanaExample of a transposable element following cancer development on spatially resolved data. In green the normal epithelium, in brown the serrated lesion, and in red the t

Updated on: December 02,2024

Jumping genes for early detection of gastric cancer

by Braulio Valdebenito-MaturanaExample of a transposable element following cancer development on spatially resolved data. In green the normal epithelium, in brown the serrated lesion, and in red the t

Updated on:December 02,2024

Innovative test that detects complex DNA patterns may improve mesothelioma detection rate in blood

by Susan Murphy,Mayo ClinicStudy design. Our study involved detecting junctions that result from chromosomal rearrangements, insertions and deletions in mesothelioma in Step 1, then designing pr

Updated on: December 02,2024

Innovative test that detects complex DNA patterns may improve mesothelioma detection rate in blood

by Susan Murphy,Mayo ClinicStudy design. Our study involved detecting junctions that result from chromosomal rearrangements, insertions and deletions in mesothelioma in Step 1, then designing pr

Updated on:December 02,2024

All in the blood: New way to detect drug resistance in ovarian cancer patients

byWalter and Eliza Hall InstituteThe "splicing" mechanism in cancer cells allows them to repair their DNA and avoid the cell death caused by PARP inhibitor therapy, resulting in drug r

Updated on: December 02,2024

All in the blood: New way to detect drug resistance in ovarian cancer patients

byWalter and Eliza Hall InstituteThe "splicing" mechanism in cancer cells allows them to repair their DNA and avoid the cell death caused by PARP inhibitor therapy, resulting in drug r

Updated on:December 02,2024

Scientists create an scRNA-seq atlas of the multiple myeloma immune microenvironment across disease stages

byVIB (the Flanders Institute for Biotechnology)The MM microenvironment is characterized by the presence of T cells with an exhausted phenotype. Credit:Journal of Hematology & Oncology

Updated on: December 02,2024

Scientists create an scRNA-seq atlas of the multiple myeloma immune microenvironment across disease stages

byVIB (the Flanders Institute for Biotechnology)The MM microenvironment is characterized by the presence of T cells with an exhausted phenotype. Credit:Journal of Hematology & Oncology

Updated on:December 02,2024

Research highlights breast cancer risk for female firefighters

bySilent Spring InstituteCredit: Pixabay/CC0 Public DomainIt's well documented that firefighters have significantly higher rates of cancer than the general population, and these elevated rat

Updated on: December 02,2024

Research highlights breast cancer risk for female firefighters

bySilent Spring InstituteCredit: Pixabay/CC0 Public DomainIt's well documented that firefighters have significantly higher rates of cancer than the general population, and these elevated rat

Updated on:December 02,2024

New therapeutic vaccine gives hope against an aggressive breast cancer

by Dennis ThompsonAn experimental vaccine could offer fresh hope to women diagnosed with an aggressive and hard-to-treat form of breast cancer, new research suggests.The vaccine appears to be safe and

Updated on: December 02,2024

New therapeutic vaccine gives hope against an aggressive breast cancer

by Dennis ThompsonAn experimental vaccine could offer fresh hope to women diagnosed with an aggressive and hard-to-treat form of breast cancer, new research suggests.The vaccine appears to be safe and

Updated on:December 02,2024

Neoantigen DNA vaccine shows promise against aggressive breast cancer in clinical trial

by Julia Evangelou Strait,Washington University School of MedicineA small clinical trial conducted at WashU Medicine shows promising results for patients with triple-negative breast cancer who r

Updated on: December 02,2024

Neoantigen DNA vaccine shows promise against aggressive breast cancer in clinical trial

by Julia Evangelou Strait,Washington University School of MedicineA small clinical trial conducted at WashU Medicine shows promising results for patients with triple-negative breast cancer who r

Updated on:December 02,2024

Novel CAR T-cell therapy demonstrates efficacy and safety in preclinical models of HER2-positive solid tumors

byVall d'Hebron Institute of OncologyGeneration and characterization of p95HER2.CART cells. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-53265-7One-third of

Updated on: December 02,2024

Novel CAR T-cell therapy demonstrates efficacy and safety in preclinical models of HER2-positive solid tumors

byVall d'Hebron Institute of OncologyGeneration and characterization of p95HER2.CART cells. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-53265-7One-third of

Updated on:December 02,2024

Why alarm is easing over a rise in pancreatic cancer among the young

by Robin FosterExperts have been concerned by rising rates of pancreatic cancer in young adults, but new research reveals the jump in cases has not been accompanied by any increase in deaths from the

Updated on: December 02,2024

Why alarm is easing over a rise in pancreatic cancer among the young

by Robin FosterExperts have been concerned by rising rates of pancreatic cancer in young adults, but new research reveals the jump in cases has not been accompanied by any increase in deaths from the

Updated on:December 02,2024

New microfluidic device shows tumor shape predicts cancer aggressiveness

byUniversity of TorontoThe image shows culture, release and transfer of the tumoroids from the ReSCUE platform, as well as the released breast cancer disk-, rod-, and U-shaped tumoroids cultured

Updated on: December 02,2024

New microfluidic device shows tumor shape predicts cancer aggressiveness

byUniversity of TorontoThe image shows culture, release and transfer of the tumoroids from the ReSCUE platform, as well as the released breast cancer disk-, rod-, and U-shaped tumoroids cultured

Updated on:December 02,2024

Research concentrates on genes that cause tumors in the Meibomian gland

byTufts UniversityDr. Cornelia Peterson calibrates a piece of equipment used to measure intraocular pressure during an ocular toxicity study in animals. Credit: Noah MossDr. Cornelia Peterson is

Updated on: December 01,2024

Research concentrates on genes that cause tumors in the Meibomian gland

byTufts UniversityDr. Cornelia Peterson calibrates a piece of equipment used to measure intraocular pressure during an ocular toxicity study in animals. Credit: Noah MossDr. Cornelia Peterson is

Updated on:December 01,2024