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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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α-KG-dependent glycolysis activation by BCAT1 contributes to EGFR-TKI resistance in NSCLC
Oncology
α-KG-dependent glycolysis activation by BCAT1 contributes to EGFR-TKI resistance in NSCLC
November 28,2024
Latest Articles
Genomic variants study points to improved detection of thyroid cancer

Genomic variants study points to improved detection of thyroid cancer

by Gabrielle Giroday,University of TorontoCredit: Unsplash/CC0 Public DomainResearchers from Sinai Health and the University of Toronto have gleaned new insights into how thyroid cancer could be
Updated on: July 06,2024 0
Genomic variants study points to improved detection of thyroid cancer

Genomic variants study points to improved detection of thyroid cancer

by Gabrielle Giroday,University of TorontoCredit: Unsplash/CC0 Public DomainResearchers from Sinai Health and the University of Toronto have gleaned new insights into how thyroid cancer could be
Updated on:July 06,2024 0
RNA splicing strategy corrects tumor suppressor gene in neuroendocrine cancers

RNA splicing strategy corrects tumor suppressor gene in neuroendocrine cancers

byOsaka UniversityGraphical abstracts. REST_SSO directly modifies REST splicing and RE1 gene expression, whereas both REST_SSO and SRRM4_ASO exhibit antitumor effects in SCLC/NEPCa. Credit: 2024
Updated on: July 05,2024 0
RNA splicing strategy corrects tumor suppressor gene in neuroendocrine cancers

RNA splicing strategy corrects tumor suppressor gene in neuroendocrine cancers

byOsaka UniversityGraphical abstracts. REST_SSO directly modifies REST splicing and RE1 gene expression, whereas both REST_SSO and SRRM4_ASO exhibit antitumor effects in SCLC/NEPCa. Credit: 2024
Updated on:July 05,2024 0
Study describes how insulinomas, a rare type of pancreatic beta cell tumor, form

Study describes how insulinomas, a rare type of pancreatic beta cell tumor, form

byUniversitat Pompeu Fabra - BarcelonaClose-up of insulinoma cells expressing insulin (red). Credit: Pompeu Fabra University (UPF)A study led by Pompeu Fabra University describes the mechanism w
Updated on: July 05,2024 0
Study describes how insulinomas, a rare type of pancreatic beta cell tumor, form

Study describes how insulinomas, a rare type of pancreatic beta cell tumor, form

byUniversitat Pompeu Fabra - BarcelonaClose-up of insulinoma cells expressing insulin (red). Credit: Pompeu Fabra University (UPF)A study led by Pompeu Fabra University describes the mechanism w
Updated on:July 05,2024 0
Bowel cancer turns genetic switches on and off to outwit the immune system, new study finds

Bowel cancer turns genetic switches on and off to outwit the immune system, new study finds

byUniversity College LondonFrameshift switching of the MSH6 C8 coding homopolymer drives stochastic loss and restoration of MSH6 expression like a molecular ON/OFF switch. Credit:Nature Ge
Updated on: July 05,2024 0
Bowel cancer turns genetic switches on and off to outwit the immune system, new study finds

Bowel cancer turns genetic switches on and off to outwit the immune system, new study finds

byUniversity College LondonFrameshift switching of the MSH6 C8 coding homopolymer drives stochastic loss and restoration of MSH6 expression like a molecular ON/OFF switch. Credit:Nature Ge
Updated on:July 05,2024 0
Engineered plasma cells show long-lasting antileukemic activity in mice

Engineered plasma cells show long-lasting antileukemic activity in mice

byCell PressAcute myelocytic leukemia (AML). Credit: Unsplash/CC0 Public DomainResearchers show for the first time that engineered human plasma B cells can be used to treat a disease—specificall
Updated on: July 05,2024 0
Engineered plasma cells show long-lasting antileukemic activity in mice

Engineered plasma cells show long-lasting antileukemic activity in mice

byCell PressAcute myelocytic leukemia (AML). Credit: Unsplash/CC0 Public DomainResearchers show for the first time that engineered human plasma B cells can be used to treat a disease—specificall
Updated on:July 05,2024 0
Mediterranean diet linked to lower risk of mortality, especially from cardiovascular disease, in cancer survivors

Mediterranean diet linked to lower risk of mortality, especially from cardiovascular disease, in cancer survivors

by Istituto Neurologico Mediterraneo Neuromed I.R.C.C.S.Credit: Unsplash/CC0 Public DomainThe Mediterranean diet is a powerful ally for health even after a cancer diagnosis. This is the key result of
Updated on: July 05,2024 0
Mediterranean diet linked to lower risk of mortality, especially from cardiovascular disease, in cancer survivors

Mediterranean diet linked to lower risk of mortality, especially from cardiovascular disease, in cancer survivors

by Istituto Neurologico Mediterraneo Neuromed I.R.C.C.S.Credit: Unsplash/CC0 Public DomainThe Mediterranean diet is a powerful ally for health even after a cancer diagnosis. This is the key result of
Updated on:July 05,2024 0
Team develops AI model to improve patient response to cancer therapy

Team develops AI model to improve patient response to cancer therapy

byAustralian National UniversityDr. Danh-Tai Hoang. Credit: The Australian National University (ANU).A new artificial intelligence (AI) tool that can help physicians to select the most suitable
Updated on: July 05,2024 0
Team develops AI model to improve patient response to cancer therapy

Team develops AI model to improve patient response to cancer therapy

byAustralian National UniversityDr. Danh-Tai Hoang. Credit: The Australian National University (ANU).A new artificial intelligence (AI) tool that can help physicians to select the most suitable
Updated on:July 05,2024 0
Destroying cancer-causing RNA could lead to bespoke treatments, say scientists

Destroying cancer-causing RNA could lead to bespoke treatments, say scientists

byPeter MacCallum Cancer CentreThe efficiency of PspCas13b silencing is highly variable between crRNAs. Credit:Nature Structural & Molecular Biology(2024). DOI: 10.1038/s41594-02
Updated on: July 05,2024 0
Destroying cancer-causing RNA could lead to bespoke treatments, say scientists

Destroying cancer-causing RNA could lead to bespoke treatments, say scientists

byPeter MacCallum Cancer CentreThe efficiency of PspCas13b silencing is highly variable between crRNAs. Credit:Nature Structural & Molecular Biology(2024). DOI: 10.1038/s41594-02
Updated on:July 05,2024 0
Study reveals CREB3's role in hepatocellular carcinoma suppression via AKT signaling

Study reveals CREB3's role in hepatocellular carcinoma suppression via AKT signaling

by Sichuan International Medical Exchange and Promotion AssociationExpression of CREB3 is decreased in HCC tissues and correlated with better clinical outcome. (A) mRNA expression of CREB3 in HCC tiss
Updated on: July 05,2024 0
Study reveals CREB3's role in hepatocellular carcinoma suppression via AKT signaling

Study reveals CREB3's role in hepatocellular carcinoma suppression via AKT signaling

by Sichuan International Medical Exchange and Promotion AssociationExpression of CREB3 is decreased in HCC tissues and correlated with better clinical outcome. (A) mRNA expression of CREB3 in HCC tiss
Updated on:July 05,2024 0
30-minute exercise session found to increase proportion of tumor-killing white blood cells in the bloodstream

30-minute exercise session found to increase proportion of tumor-killing white blood cells in the bloodstream

byUniversity of TurkuExercise-induced changes in (A) total T cells, (B) CD4+helper T cells, (C) Th1 cells, (D) Th2 cells, (E) Th17 cells, (F) regulatory T cells, (G) CD8+cytotoxic T
Updated on: July 05,2024 0
30-minute exercise session found to increase proportion of tumor-killing white blood cells in the bloodstream

30-minute exercise session found to increase proportion of tumor-killing white blood cells in the bloodstream

byUniversity of TurkuExercise-induced changes in (A) total T cells, (B) CD4+helper T cells, (C) Th1 cells, (D) Th2 cells, (E) Th17 cells, (F) regulatory T cells, (G) CD8+cytotoxic T
Updated on:July 05,2024 0
Re-engineering cancerous tumors to self-destruct and kill drug-resistant cells

Re-engineering cancerous tumors to self-destruct and kill drug-resistant cells

byPennsylvania State UniversityCredit: Unsplash/CC0 Public DomainTreating cancer can sometimes feel like a game of Whac-A-Mole. The disease can become resistant to treatment, and clinicians neve
Updated on: July 05,2024 0
Re-engineering cancerous tumors to self-destruct and kill drug-resistant cells

Re-engineering cancerous tumors to self-destruct and kill drug-resistant cells

byPennsylvania State UniversityCredit: Unsplash/CC0 Public DomainTreating cancer can sometimes feel like a game of Whac-A-Mole. The disease can become resistant to treatment, and clinicians neve
Updated on:July 05,2024 0
Genetic test improves clinical care for children with cancer in England

Genetic test improves clinical care for children with cancer in England

byWellcome Trust Sanger InstituteCredit: Unsplash/CC0 Public DomainWhole genome sequencing has improved clinical care of some children with cancer in England by informing individual patient care
Updated on: July 05,2024 0
Genetic test improves clinical care for children with cancer in England

Genetic test improves clinical care for children with cancer in England

byWellcome Trust Sanger InstituteCredit: Unsplash/CC0 Public DomainWhole genome sequencing has improved clinical care of some children with cancer in England by informing individual patient care
Updated on:July 05,2024 0
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