Study highlights promising drug combination for treating resistant breast cancer

by Lisa Marshall,University of Colorado at BoulderCredit:Cell(2023). DOI: 10.1016/j.cell.2023.05.013Cancer cells are even smarter than scientists previously believed, according to ne

Updated on: February 03,2024 15

Study highlights promising drug combination for treating resistant breast cancer

by Lisa Marshall,University of Colorado at BoulderCredit:Cell(2023). DOI: 10.1016/j.cell.2023.05.013Cancer cells are even smarter than scientists previously believed, according to ne

Updated on:February 03,2024 15

Research raises hopes for new treatment of fusion-driven cancer

by Aarhus UniversityFusion-gene disruption strategy.ADual intron-targeting CRISPR-Cas9-mediated disruption ofRUNX1-RUNX1T1. sgRNAs targeting intron 4 ofRUNX1(orange)

Updated on: February 03,2024 10

Research raises hopes for new treatment of fusion-driven cancer

by Aarhus UniversityFusion-gene disruption strategy.ADual intron-targeting CRISPR-Cas9-mediated disruption ofRUNX1-RUNX1T1. sgRNAs targeting intron 4 ofRUNX1(orange)

Updated on:February 03,2024 10

Researchers identify needs of rural-based physicians to optimize cancer survivorship care

by University of MissouriCredit: Unsplash/CC0 Public DomainThe vast majority of cancer survivors rely on primary care clinicians for follow-up treatments, especially in rural areas, according to

Updated on: February 03,2024 13

Researchers identify needs of rural-based physicians to optimize cancer survivorship care

by University of MissouriCredit: Unsplash/CC0 Public DomainThe vast majority of cancer survivors rely on primary care clinicians for follow-up treatments, especially in rural areas, according to

Updated on:February 03,2024 13

Neutralizing the side effects of epidermal growth factor inhibitor drugs

by Justin Jackson , Medical XpressIdentifying compounds that block anti-EGFR monoclonal antibodies binding to EGFR. (A) Illustration of the process used to identify lead compounds. "Hit" mol

Updated on: February 03,2024 19

Neutralizing the side effects of epidermal growth factor inhibitor drugs

by Justin Jackson , Medical XpressIdentifying compounds that block anti-EGFR monoclonal antibodies binding to EGFR. (A) Illustration of the process used to identify lead compounds. "Hit" mol

Updated on:February 03,2024 19

Study discovers novel molecular mechanism driving chemoresistance and tumor recurrence in gastric cancer

by The University of Hong KongProposed model for chemoresistance driven by ADAR1-upregulated SCD1 in gastric cancer. Credit:Nature Communications(2023). DOI: 10.1038/s41467-023-38581-

Updated on: February 03,2024 15

Study discovers novel molecular mechanism driving chemoresistance and tumor recurrence in gastric cancer

by The University of Hong KongProposed model for chemoresistance driven by ADAR1-upregulated SCD1 in gastric cancer. Credit:Nature Communications(2023). DOI: 10.1038/s41467-023-38581-

Updated on:February 03,2024 15

Researchers advance CRISPR technology to replicate human diseases with unprecedented accuracy

by Walter and Eliza Hall Institute of Medical ResearchGeneration and validation of pdCas9a-SAM construct in Eµ-Myc lymphoma cell lines. a Schematic representation of the pdCas9a-SAM lentiviral co

Updated on: February 03,2024 19

Researchers advance CRISPR technology to replicate human diseases with unprecedented accuracy

by Walter and Eliza Hall Institute of Medical ResearchGeneration and validation of pdCas9a-SAM construct in Eµ-Myc lymphoma cell lines. a Schematic representation of the pdCas9a-SAM lentiviral co

Updated on:February 03,2024 19

Researchers discover crucial step in creating blood stem cells

by Iowa State UniversityBlood stem cells show forming in the trunk of a zebrafish embryo. The blood stem cells are yellow, with the red tubes are the aorta on the top and a vein on the bottom. Cr

Updated on: February 03,2024 20

Researchers discover crucial step in creating blood stem cells

by Iowa State UniversityBlood stem cells show forming in the trunk of a zebrafish embryo. The blood stem cells are yellow, with the red tubes are the aorta on the top and a vein on the bottom. Cr

Updated on:February 03,2024 20

Study provides new look at why rare cancer often evades treatments

by Boston Medical CenterCharacterizing the cellular landscape of pancreatic, small intestinal, and gNETs. (A) NET scRNA-seq workflow. Resected tumor fragments were dissociated into single-cell su

Updated on: February 03,2024 14

Study provides new look at why rare cancer often evades treatments

by Boston Medical CenterCharacterizing the cellular landscape of pancreatic, small intestinal, and gNETs. (A) NET scRNA-seq workflow. Resected tumor fragments were dissociated into single-cell su

Updated on:February 03,2024 14

Study explains how 'zombie' cancer cells revive themselves

by Andrew Smith,Rutgers UniversityGraphical abstract. Credit:Cell Genomics(2023). DOI: 10.1016/j.xgen.2023.100293Mutating cells can prevent the spread of cancer by flipping themselve

Updated on: February 03,2024 14

Study explains how 'zombie' cancer cells revive themselves

by Andrew Smith,Rutgers UniversityGraphical abstract. Credit:Cell Genomics(2023). DOI: 10.1016/j.xgen.2023.100293Mutating cells can prevent the spread of cancer by flipping themselve

Updated on:February 03,2024 14

Team identifies the cells responsible for colon cancer relapse

by Institute for Research in Biomedicine (IRB Barcelona)Colorectal cancer organoids, edited to express a tdTomato reporter in cells with high Epithelial membrane protein 1 (Emp1) expression, were

Updated on: February 03,2024 14

Team identifies the cells responsible for colon cancer relapse

by Institute for Research in Biomedicine (IRB Barcelona)Colorectal cancer organoids, edited to express a tdTomato reporter in cells with high Epithelial membrane protein 1 (Emp1) expression, were

Updated on:February 03,2024 14

Survival similar for Black, White prostate cancer patients in clinical trial setting

by Elana GotkineFor metastatic castration-sensitive prostate cancer (mCSPC), overall survival and progression-free survival are similar for Black and White patients receiving first- or second-generati

Updated on: February 03,2024 15

Survival similar for Black, White prostate cancer patients in clinical trial setting

by Elana GotkineFor metastatic castration-sensitive prostate cancer (mCSPC), overall survival and progression-free survival are similar for Black and White patients receiving first- or second-generati

Updated on:February 03,2024 15

Research reveals potential targets for therapeutic development for glioblastoma

by Amy Richardson,University of Alabama at BirminghamGraphical abstract. Credit:JCI Insight(2022). DOI: 10.1172/jci.insight.148717The University of Alabama at Birmingham Marnix E. He

Updated on: February 03,2024 18

Research reveals potential targets for therapeutic development for glioblastoma

by Amy Richardson,University of Alabama at BirminghamGraphical abstract. Credit:JCI Insight(2022). DOI: 10.1172/jci.insight.148717The University of Alabama at Birmingham Marnix E. He

Updated on:February 03,2024 18