BRCA Exchange aggregates data on thousands of BRCA variants to understand cancer risk

by National Cancer InstituteCredit: National Cancer InstituteA global resource that includes data on thousands of inherited variants in the BRCA1 and BRCA2 genes is available to the public. The B

Updated on: March 30,2024

BRCA Exchange aggregates data on thousands of BRCA variants to understand cancer risk

by National Cancer InstituteCredit: National Cancer InstituteA global resource that includes data on thousands of inherited variants in the BRCA1 and BRCA2 genes is available to the public. The B

Updated on:March 30,2024

When combined, a novel LSD1 inhibitor and an existing therapy enhance each other's anti-cancer effects

by Jaclyn Dunne,Medical University of South CarolinaGraphical abstract. Credit:European Journal of Medicinal Chemistry(2022). DOI: 10.1016/j.ejmech.2022.114818A Medical University of

Updated on: December 20,2023

When combined, a novel LSD1 inhibitor and an existing therapy enhance each other's anti-cancer effects

by Jaclyn Dunne,Medical University of South CarolinaGraphical abstract. Credit:European Journal of Medicinal Chemistry(2022). DOI: 10.1016/j.ejmech.2022.114818A Medical University of

Updated on:December 20,2023

Structural analysis reveals an unexpected mechanism for a cancer drug

by Tim Stephens,University of California - Santa CruzThe breast cancer drug palbociclib (grey) interacts with its target protein CDK4 (green) in this structural model. Binding of the activator p

Updated on: December 22,2023

Structural analysis reveals an unexpected mechanism for a cancer drug

by Tim Stephens,University of California - Santa CruzThe breast cancer drug palbociclib (grey) interacts with its target protein CDK4 (green) in this structural model. Binding of the activator p

Updated on:December 22,2023

Cancer biomarker data is not diverse, with implications for immunotherapy patients from underrepresented groups

byCell PressCredit: Pixabay/CC0 Public DomainHigh tumor mutational burden—the number of mutations found inside cancer cells—may not generalize as an accurate biomarker across diverse cancer pati

Updated on: December 18,2023

Cancer biomarker data is not diverse, with implications for immunotherapy patients from underrepresented groups

byCell PressCredit: Pixabay/CC0 Public DomainHigh tumor mutational burden—the number of mutations found inside cancer cells—may not generalize as an accurate biomarker across diverse cancer pati

Updated on:December 18,2023

Residual cancer burden after neoadjuvant therapy can accurately predict breast cancer survival

byUniversity of Texas M. D. Anderson Cancer CenterW. Fraser Symmans, M.D. Credit: MD Anderson Cancer CenterResearchers from The University of Texas MD Anderson Cancer Center today reported resul

Updated on: December 22,2023

Residual cancer burden after neoadjuvant therapy can accurately predict breast cancer survival

byUniversity of Texas M. D. Anderson Cancer CenterW. Fraser Symmans, M.D. Credit: MD Anderson Cancer CenterResearchers from The University of Texas MD Anderson Cancer Center today reported resul

Updated on:December 22,2023

Cancers engaged in evolutionary arms race with immune system

byInstitute of Cancer ResearchMultiplex immunohistochemistry image of T-cells infiltrating stomach tumours. Credit: Katharina von Loga, Biomedical Research CentreAggressive, highly mutated cance

Updated on: December 22,2023

Cancers engaged in evolutionary arms race with immune system

byInstitute of Cancer ResearchMultiplex immunohistochemistry image of T-cells infiltrating stomach tumours. Credit: Katharina von Loga, Biomedical Research CentreAggressive, highly mutated cance

Updated on:December 22,2023

Experts assess promise of vamorolone to treat Duchenne muscular dystrophy

by IOS PressSkeletal muscle fibers. Credit: Berkshire Community College Bioscience Image Library / Public domainThe drug vamorolone (Agamree) has been hailed as a promising new drug to treat Duch

Updated on: May 26,2024

Experts assess promise of vamorolone to treat Duchenne muscular dystrophy

by IOS PressSkeletal muscle fibers. Credit: Berkshire Community College Bioscience Image Library / Public domainThe drug vamorolone (Agamree) has been hailed as a promising new drug to treat Duch

Updated on:May 26,2024

Researchers identify path to prevent cognitive decline after radiation

by Kelsie Smith Hayduk,University of Rochester Medical CenterCredit: Pixabay/CC0 Public DomainResearchers at the Del Monte Institute for Neuroscience at the University of Rochester find that mic

Updated on: January 09,2024

Researchers identify path to prevent cognitive decline after radiation

by Kelsie Smith Hayduk,University of Rochester Medical CenterCredit: Pixabay/CC0 Public DomainResearchers at the Del Monte Institute for Neuroscience at the University of Rochester find that mic

Updated on:January 09,2024

Non-hormonal therapy reduces hot flashes and night sweats in women who have been diagnosed with breast cancer

by Cheryl Critchley,Monash UniversityCredit: Pixabay/CC0 Public DomainA Monash University-led trial of a new drug known as Q-122 therapy significantly reduced the number and severity of hot flas

Updated on: December 22,2023

Non-hormonal therapy reduces hot flashes and night sweats in women who have been diagnosed with breast cancer

by Cheryl Critchley,Monash UniversityCredit: Pixabay/CC0 Public DomainA Monash University-led trial of a new drug known as Q-122 therapy significantly reduced the number and severity of hot flas

Updated on:December 22,2023

Researchers discover compound that fights leukemia and lymphoma

JANUARY 12, 2024byUniversity of Texas at El PasoRenato Aguilera, Ph.D., a professor in the Department of Biological Sciences at The University of Texas at El Paso, is the principal investigator

Updated on: March 28,2024

Researchers discover compound that fights leukemia and lymphoma

JANUARY 12, 2024byUniversity of Texas at El PasoRenato Aguilera, Ph.D., a professor in the Department of Biological Sciences at The University of Texas at El Paso, is the principal investigator

Updated on:March 28,2024

Serotonin-producing neurons regulate malignancy in ependymoma brain tumors

byBaylor College of MedicineStimulation of serotonergic neurons suppresses EPN tumorigenesis. Credit:Nature(2024). DOI: 10.1038/s41586-024-07751-zA study published inNature&nbs

Updated on: August 26,2024

Serotonin-producing neurons regulate malignancy in ependymoma brain tumors

byBaylor College of MedicineStimulation of serotonergic neurons suppresses EPN tumorigenesis. Credit:Nature(2024). DOI: 10.1038/s41586-024-07751-zA study published inNature&nbs

Updated on:August 26,2024

Point-of-care biosensor rapidly detects oral cancer

byAmerican Institute of PhysicsPhoto of the group’s circuit board for the biosensor. Credit: Minghan Xian, Jenna L. Stephany, Chan-Wen Chiu, Chao-Cing Chiang, Fan Ren, Cheng-Tse Tsai, Siang-Sin

Updated on: December 25,2023

Point-of-care biosensor rapidly detects oral cancer

byAmerican Institute of PhysicsPhoto of the group’s circuit board for the biosensor. Credit: Minghan Xian, Jenna L. Stephany, Chan-Wen Chiu, Chao-Cing Chiang, Fan Ren, Cheng-Tse Tsai, Siang-Sin

Updated on:December 25,2023