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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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Adcetris FDA approval expanded to include later-stage Hodgkin's

Adcetris FDA approval expanded to include later-stage Hodgkin's

(HealthDay)—U.S. Food and Drug Administration approval of Adcetris (brentuximab vedotin) has been expanded to include adults with untreated stage III or IV classical Hodgkin's lymphoma, the agency

Adcetris FDA approval expanded to include later-stage Hodgkin's

(HealthDay)—U.S. Food and Drug Administration approval of Adcetris (brentuximab vedotin) has been expanded to include adults with untreated stage III or IV classical Hodgkin's lymphoma, the agency
Researchers identify novel gene networks associated with aggressive type of breast cancer

Researchers identify novel gene networks associated with aggressive type of breast cancer

by Savannah Williamson,Georgia Institute of TechnologyGene enrichment for select Basal-like network modules. Network diagram for eight nonconserved Basal-like modules that include OS genes. Node

Researchers identify novel gene networks associated with aggressive type of breast cancer

by Savannah Williamson,Georgia Institute of TechnologyGene enrichment for select Basal-like network modules. Network diagram for eight nonconserved Basal-like modules that include OS genes. Node
Metastasizing cancer cells modify bone remodeling with small RNA secretion

Metastasizing cancer cells modify bone remodeling with small RNA secretion

by Tokyo Medical and Dental UniversityIn the bone metastatic microenvironment, the crosstalk between metastasized cancer cells and the surrounding bone cells is critical for the formation of the osteo

Metastasizing cancer cells modify bone remodeling with small RNA secretion

by Tokyo Medical and Dental UniversityIn the bone metastatic microenvironment, the crosstalk between metastasized cancer cells and the surrounding bone cells is critical for the formation of the osteo
Age, cancer type affect COVID-19 vaccine uptake in cancer patients

Age, cancer type affect COVID-19 vaccine uptake in cancer patients

by Elana GotkineFor patients with cancer, age, cancer type, and comorbidity are associated with differential COVID-19 vaccine uptake rates, according to a study published online March 15 inCance

Age, cancer type affect COVID-19 vaccine uptake in cancer patients

by Elana GotkineFor patients with cancer, age, cancer type, and comorbidity are associated with differential COVID-19 vaccine uptake rates, according to a study published online March 15 inCance
Scientists consider fighting potentially lethal form of breast cancer with chemical produced by the disease

Scientists consider fighting potentially lethal form of breast cancer with chemical produced by the disease

by Delthia Ricks , Medical XpressSchematic model of GDP-M regulating HRD and immunity through promoting BRCA2 degradation. Credit:Science Translational Medicine(2024). DOI: 10.1126/scitran

Scientists consider fighting potentially lethal form of breast cancer with chemical produced by the disease

by Delthia Ricks , Medical XpressSchematic model of GDP-M regulating HRD and immunity through promoting BRCA2 degradation. Credit:Science Translational Medicine(2024). DOI: 10.1126/scitran
New review on p53 biology and reactivation in blood cancers

New review on p53 biology and reactivation in blood cancers

byKarolinska InstitutetA simplified scheme of p53 regulation in cells upon stress and the drugs currently evaluated in clinical trials for p53 reactivation for improved therapy in MDS and AML. C

New review on p53 biology and reactivation in blood cancers

byKarolinska InstitutetA simplified scheme of p53 regulation in cells upon stress and the drugs currently evaluated in clinical trials for p53 reactivation for improved therapy in MDS and AML. C
Study identifies new treatment target for metastatic cancer

Study identifies new treatment target for metastatic cancer

by Elizabeth Chapin,University of KentuckySuccinate levels are elevated during EMT. (A) Expression of EMT markers was assessed by western blot in control, Snail1- and Twist1-expressing HMLE cell

Study identifies new treatment target for metastatic cancer

by Elizabeth Chapin,University of KentuckySuccinate levels are elevated during EMT. (A) Expression of EMT markers was assessed by western blot in control, Snail1- and Twist1-expressing HMLE cell
Researchers identify a new biomarker for personalised treatments against cancer

Researchers identify a new biomarker for personalised treatments against cancer

by Institute for Research in Biomedicine (IRB Barcelona)Different localization of the proteins involved in apoptosis in basal (Ctrl) and upon death receptor induction with TRAIL. Credit: Saška Iv

Researchers identify a new biomarker for personalised treatments against cancer

by Institute for Research in Biomedicine (IRB Barcelona)Different localization of the proteins involved in apoptosis in basal (Ctrl) and upon death receptor induction with TRAIL. Credit: Saška Iv
Experimental monoclonal antibodies can coax aggressive prostate and breast cancers into submission, finds research

Experimental monoclonal antibodies can coax aggressive prostate and breast cancers into submission, finds research

by Delthia Ricks , Medical XpressTherapeutic inhibition of VEGF binding to NRP2 activates anti-tumor immunity in a syngeneic model of prostate cancer that is resistant to aPD-L1 therapy. (A) Shown is

Experimental monoclonal antibodies can coax aggressive prostate and breast cancers into submission, finds research

by Delthia Ricks , Medical XpressTherapeutic inhibition of VEGF binding to NRP2 activates anti-tumor immunity in a syngeneic model of prostate cancer that is resistant to aPD-L1 therapy. (A) Shown is
Study: B cells promote liver cancer with dangerous dual strategy

Study: B cells promote liver cancer with dangerous dual strategy

byGerman Cancer Research CenterGraphical Abstract. Credit:Journal of Hepatology(2023). DOI: 10.1016/j.jhep.2023.04.037Inflammatory fatty liver disease (NASH, non alcoholic steatohepa

Study: B cells promote liver cancer with dangerous dual strategy

byGerman Cancer Research CenterGraphical Abstract. Credit:Journal of Hepatology(2023). DOI: 10.1016/j.jhep.2023.04.037Inflammatory fatty liver disease (NASH, non alcoholic steatohepa

by Niigata UniversityCredit: Unsplash/CC0 Public DomainAn international team led by the Department of Neurosurgery, Niigata University, has identified a new gene called Schlafen11 (SLFN11) whose expre

by Niigata UniversityCredit: Unsplash/CC0 Public DomainAn international team led by the Department of Neurosurgery, Niigata University, has identified a new gene called Schlafen11 (SLFN11) whose expre
Researchers to test novel drug combination against toughest breast cancers

Researchers to test novel drug combination against toughest breast cancers

by University of California - San DiegoThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Credit: National Ins

Researchers to test novel drug combination against toughest breast cancers

by University of California - San DiegoThree-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Credit: National Ins