Lost metabolic fitness of CAR NK cells is key mechanism of tumor resistance, study discovers

byUniversity of Texas M. D. Anderson Cancer CenterCAR-NK cells have a distinct single-cell transcriptome and metabolic profile. Credit:Science Advances(2023). DOI: 10.1126/sciadv.add

Updated on: January 23,2024

Lost metabolic fitness of CAR NK cells is key mechanism of tumor resistance, study discovers

byUniversity of Texas M. D. Anderson Cancer CenterCAR-NK cells have a distinct single-cell transcriptome and metabolic profile. Credit:Science Advances(2023). DOI: 10.1126/sciadv.add

Updated on:January 23,2024

Using donor CAR T cells shows promise in treating myeloma patients in phase I trial

by Bob Yirka , Medical XpressCAR T Cell Concentrations Stratified by Response. (a) CAR T cell concentrations among ALLO-715 DL3 patients that received any fludarabine/cyclophosphamide/ALLO-647 (FCA) l

Updated on: February 03,2024

Using donor CAR T cells shows promise in treating myeloma patients in phase I trial

by Bob Yirka , Medical XpressCAR T Cell Concentrations Stratified by Response. (a) CAR T cell concentrations among ALLO-715 DL3 patients that received any fludarabine/cyclophosphamide/ALLO-647 (FCA) l

Updated on:February 03,2024

Researchers investigate effects of pharmacological antioxidant compound DPDT on tumor cells

by Impact Journals LLCApoptosis induction by DPDT. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28465A new research paper has been published in the journalOncotargetentitled, &q

Updated on: February 18,2024

Researchers investigate effects of pharmacological antioxidant compound DPDT on tumor cells

by Impact Journals LLCApoptosis induction by DPDT. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28465A new research paper has been published in the journalOncotargetentitled, &q

Updated on:February 18,2024

Study finds behavior matters far more to lifetime exposure to cancer-causing radiation than previously believed

by Allie Miller,University of CalgaryResidential radon exposure periods modified by radon awareness behavior and test decision-making that can differ by age, sex/gender or parental status. Credi

Updated on: January 23,2024

Study finds behavior matters far more to lifetime exposure to cancer-causing radiation than previously believed

by Allie Miller,University of CalgaryResidential radon exposure periods modified by radon awareness behavior and test decision-making that can differ by age, sex/gender or parental status. Credi

Updated on:January 23,2024

Second primary malignancy risk increased after cutaneous B-cell lymphoma

by Elana GotkinePatients with primary cutaneous B-cell lymphomas (PCBCLs) have an increased risk for second primary malignancies (SPMs), according to a studypublishedonline March 19 in the

Updated on: April 06,2024

Second primary malignancy risk increased after cutaneous B-cell lymphoma

by Elana GotkinePatients with primary cutaneous B-cell lymphomas (PCBCLs) have an increased risk for second primary malignancies (SPMs), according to a studypublishedonline March 19 in the

Updated on:April 06,2024

Specifically designed diets demonstrate a 'powerful ability' to prevent tumorigenesis, delay tumor growth

byThe Spanish National Cancer Research CentrePrecision nutrition in cancer therapyPrecision nutrition takes into account genetic, physiological and lifestyle factors to develop personalized diet

Updated on: January 22,2024

Specifically designed diets demonstrate a 'powerful ability' to prevent tumorigenesis, delay tumor growth

byThe Spanish National Cancer Research CentrePrecision nutrition in cancer therapyPrecision nutrition takes into account genetic, physiological and lifestyle factors to develop personalized diet

Updated on:January 22,2024

'Positive' trial for Pfizer-BioNTech COVID-flu jab

Credit: Unsplash/CC0 Public DomainGermany's BioNTech and US pharmaceutical giant Pfizer on Thursday announced "positive" results from initial trials of their combined mRNA vaccine agains

Updated on: March 01,2024

'Positive' trial for Pfizer-BioNTech COVID-flu jab

Credit: Unsplash/CC0 Public DomainGermany's BioNTech and US pharmaceutical giant Pfizer on Thursday announced "positive" results from initial trials of their combined mRNA vaccine agains

Updated on:March 01,2024

Merck, Moderna detail potential skin cancer vaccine progress

by Tom MurphyA sign marks an entrance to a Moderna building in Cambridge, Mass., on Monday, May 18, 2020. Shares of Merck and Moderna jumped early Tuesday, Dec. 13, 2022, after the drugmakers said a p

Updated on: January 02,2024

Merck, Moderna detail potential skin cancer vaccine progress

by Tom MurphyA sign marks an entrance to a Moderna building in Cambridge, Mass., on Monday, May 18, 2020. Shares of Merck and Moderna jumped early Tuesday, Dec. 13, 2022, after the drugmakers said a p

Updated on:January 02,2024

Intraventricular immunovirotherapy: A translational step forward

by Impact JournalsPutative mechanisms of toxicity. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28343A new research perspective titled "Intraventricular immunovirotherapy; a tran

Updated on: January 02,2024

Intraventricular immunovirotherapy: A translational step forward

by Impact JournalsPutative mechanisms of toxicity. Credit:Oncotarget(2023). DOI: 10.18632/oncotarget.28343A new research perspective titled "Intraventricular immunovirotherapy; a tran

Updated on:January 02,2024

New research results explore the safety of short-term cultivated CAR T cells in cancer immunotherapy

by Susanne Stöcker, Paul-Ehrlich-Institut - Bundesinstitut für Impfstoffe und biomedizinische ArzneimittelTo make CAR T cells available to all patients, various strategies facilitating the manufacturi

Updated on: March 30,2024

New research results explore the safety of short-term cultivated CAR T cells in cancer immunotherapy

by Susanne Stöcker, Paul-Ehrlich-Institut - Bundesinstitut für Impfstoffe und biomedizinische ArzneimittelTo make CAR T cells available to all patients, various strategies facilitating the manufacturi

Updated on:March 30,2024

Supercharging immunotherapy to stop breast cancer from spreading to the lung

byUniversity of GlasgowGraphical abstract. Credit:Journal of Experimental Medicine(2022). DOI: 10.1084/jem.20211431Breast cancer immunotherapy could be more effective if an immune ce

Updated on: January 02,2024

Supercharging immunotherapy to stop breast cancer from spreading to the lung

byUniversity of GlasgowGraphical abstract. Credit:Journal of Experimental Medicine(2022). DOI: 10.1084/jem.20211431Breast cancer immunotherapy could be more effective if an immune ce

Updated on:January 02,2024

Immune checkpoint blockade prior to surgery promising in multiple cancer types, finds study

byJohns Hopkins University School of MedicineThis graphic highlights the vast scientific research opportunities associated with neoadjuvant immune checkpoint blockade. Credit:Cancer CellTr

Updated on: January 23,2024

Immune checkpoint blockade prior to surgery promising in multiple cancer types, finds study

byJohns Hopkins University School of MedicineThis graphic highlights the vast scientific research opportunities associated with neoadjuvant immune checkpoint blockade. Credit:Cancer CellTr

Updated on:January 23,2024