Drug combination provides a one-two punch attack against colorectal cancer

by National Cancer InstituteOn the left,SN38, the active metabolite of irinotecan, traps TOP1 on DNA, forming TOP1 cleavage complexes that are degraded upon their formation, as seen by the

Updated on: January 29,2024

Drug combination provides a one-two punch attack against colorectal cancer

by National Cancer InstituteOn the left,SN38, the active metabolite of irinotecan, traps TOP1 on DNA, forming TOP1 cleavage complexes that are degraded upon their formation, as seen by the

Updated on:January 29,2024

Potent results from a new immune treatment seen in patients with hard-to-treat blood cancers

by Peter MacCallum Cancer CentreCredit: Pixabay/CC0 Public DomainAll patients in the Phase I / II clinical trial of glofitamab had Diffuse Large B-Cell Lymphoma (DLBCL) and their cancer had relapsed o

Updated on: January 29,2024

Potent results from a new immune treatment seen in patients with hard-to-treat blood cancers

by Peter MacCallum Cancer CentreCredit: Pixabay/CC0 Public DomainAll patients in the Phase I / II clinical trial of glofitamab had Diffuse Large B-Cell Lymphoma (DLBCL) and their cancer had relapsed o

Updated on:January 29,2024

Triple-drug therapy for post-transplant management of multiple myeloma

by University of Chicago Medical CenterCredit: Unsplash/CC0 Public DomainResearchers from the University of Chicago Medicine Comprehensive Cancer Center and colleagues in Poland report promising

Updated on: February 18,2024

Triple-drug therapy for post-transplant management of multiple myeloma

by University of Chicago Medical CenterCredit: Unsplash/CC0 Public DomainResearchers from the University of Chicago Medicine Comprehensive Cancer Center and colleagues in Poland report promising

Updated on:February 18,2024

A new approach to targeting tumors and tracking their spread

by Massachusetts Institute of TechnologyKiller T cells surround a cancer cell. Credit: NIHThe spread of malignant cells from an original tumor to other parts of the body, known as metastasis, is

Updated on: May 20,2024

A new approach to targeting tumors and tracking their spread

by Massachusetts Institute of TechnologyKiller T cells surround a cancer cell. Credit: NIHThe spread of malignant cells from an original tumor to other parts of the body, known as metastasis, is

Updated on:May 20,2024

Researchers develop affordable, rapid blood test for brain cancer

by Brandi Wampler,University of Notre DameThe biochip is used to detect biomarkers for glioblastoma, a fast-growing brain cancer. Credit: Matt Cashore / University of Notre DameResearchers at th

Updated on: September 07,2024

Researchers develop affordable, rapid blood test for brain cancer

by Brandi Wampler,University of Notre DameThe biochip is used to detect biomarkers for glioblastoma, a fast-growing brain cancer. Credit: Matt Cashore / University of Notre DameResearchers at th

Updated on:September 07,2024

Colorectal cancer: New approach for better efficacy of immunotherapies

byMedical University of ViennaSingle-cell RNA- and TCR sequencing reveal favored Vδ1+ usage with expanded CDR3 identity patterns in γδ T cells of MSS CRC. Credit:Nature Communications&nbsp

Updated on: September 07,2024

Colorectal cancer: New approach for better efficacy of immunotherapies

byMedical University of ViennaSingle-cell RNA- and TCR sequencing reveal favored Vδ1+ usage with expanded CDR3 identity patterns in γδ T cells of MSS CRC. Credit:Nature Communications&nbsp

Updated on:September 07,2024

Researchers identify a process responsible for therapeutic resistance in breast cancer

by McGill UniversityMammograms showing a normal breast (left) and a breast with cancer (right). Credit: Public DomainResearchers at the Lady Davis Institute have identified a key protein that is

Updated on: March 01,2024

Researchers identify a process responsible for therapeutic resistance in breast cancer

by McGill UniversityMammograms showing a normal breast (left) and a breast with cancer (right). Credit: Public DomainResearchers at the Lady Davis Institute have identified a key protein that is

Updated on:March 01,2024

Researchers identify women with twice the risk of cancer in both breasts

by Mayo ClinicCumulative incidence of CBC risk in PV carriers. Cumulative incidence plots for first contralateral breast cancers after primary breast cancer. Cumulative incidence is plotted again

Updated on: February 18,2024

Researchers identify women with twice the risk of cancer in both breasts

by Mayo ClinicCumulative incidence of CBC risk in PV carriers. Cumulative incidence plots for first contralateral breast cancers after primary breast cancer. Cumulative incidence is plotted again

Updated on:February 18,2024

Combination therapy outperforms chemotherapy in clinical trial for patients with chronic lymphocytic leukemia

by University of AmsterdamCredit: Unsplash/CC0 Public DomainChemotherapy has been the most effective treatment to date for young and fit patients with chronic lymphocytic leukemia (CLL). The dise

Updated on: February 03,2024

Combination therapy outperforms chemotherapy in clinical trial for patients with chronic lymphocytic leukemia

by University of AmsterdamCredit: Unsplash/CC0 Public DomainChemotherapy has been the most effective treatment to date for young and fit patients with chronic lymphocytic leukemia (CLL). The dise

Updated on:February 03,2024

Nudging both clinicians and patients may increase serious illness conversations

by Lori SolomonCombining clinician- and patient-directed nudges may help to promote serious illness conversations (SICs) in cancer care, according to a studypublishedonline July 1 in

Updated on: July 05,2024

Nudging both clinicians and patients may increase serious illness conversations

by Lori SolomonCombining clinician- and patient-directed nudges may help to promote serious illness conversations (SICs) in cancer care, according to a studypublishedonline July 1 in

Updated on:July 05,2024

Combination therapy overcomes BET inhibitor resistance, shows study

bySt. Jude Children's Research HospitalStudy first author Shaela Fields (Wright), from the lab of Chunliang, Li, PhD, St. Jude Department of Tumor Cell Biology, led research to understand BE

Updated on: January 16,2024

Combination therapy overcomes BET inhibitor resistance, shows study

bySt. Jude Children's Research HospitalStudy first author Shaela Fields (Wright), from the lab of Chunliang, Li, PhD, St. Jude Department of Tumor Cell Biology, led research to understand BE

Updated on:January 16,2024

Researchers identify innovative strategy with potential to enhance bowel cancer treatment

by University of GalwayGraphical Abstract. Credit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.112475Researchers at University of Galway studying cell interactions in bowel cancer h

Updated on: February 18,2024

Researchers identify innovative strategy with potential to enhance bowel cancer treatment

by University of GalwayGraphical Abstract. Credit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.112475Researchers at University of Galway studying cell interactions in bowel cancer h

Updated on:February 18,2024