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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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Men over 40 with BRCA2 gene fault should get regular PSA screening, experts say

Men over 40 with BRCA2 gene fault should get regular PSA screening, experts say

by Institute of Cancer Research, LondonCredit: CC0 Public DomainGuidelines should change so that all men over the age of 40 with faults in the BRCA2 gene should be offered regular PSA testing to detec

Men over 40 with BRCA2 gene fault should get regular PSA screening, experts say

by Institute of Cancer Research, LondonCredit: CC0 Public DomainGuidelines should change so that all men over the age of 40 with faults in the BRCA2 gene should be offered regular PSA testing to detec
RNA splicing strategy corrects tumor suppressor gene in neuroendocrine cancers

RNA splicing strategy corrects tumor suppressor gene in neuroendocrine cancers

byOsaka UniversityGraphical abstracts. REST_SSO directly modifies REST splicing and RE1 gene expression, whereas both REST_SSO and SRRM4_ASO exhibit antitumor effects in SCLC/NEPCa. Credit: 2024

RNA splicing strategy corrects tumor suppressor gene in neuroendocrine cancers

byOsaka UniversityGraphical abstracts. REST_SSO directly modifies REST splicing and RE1 gene expression, whereas both REST_SSO and SRRM4_ASO exhibit antitumor effects in SCLC/NEPCa. Credit: 2024
Researchers report results in rare gynecologic cancers from DART immunotherapy trial

Researchers report results in rare gynecologic cancers from DART immunotherapy trial

by SWOG Cancer Research NetworkCredit: Unsplash/CC0 Public DomainResults from the S1609 DART clinical trial, which tested an immunotherapy combination of ipilimumab plus nivolumab in 53 cohorts of pat

Researchers report results in rare gynecologic cancers from DART immunotherapy trial

by SWOG Cancer Research NetworkCredit: Unsplash/CC0 Public DomainResults from the S1609 DART clinical trial, which tested an immunotherapy combination of ipilimumab plus nivolumab in 53 cohorts of pat
Heart disease prevention is particularly important in cancer patients

Heart disease prevention is particularly important in cancer patients

by Johannes Angerer,Medical University of ViennaBaseline cardiovascular toxicity risk assessment checklist. BNP, B-type natriuretic peptide; cTn, cardiac troponin; CTR-CVT, cancer therapy-relate

Heart disease prevention is particularly important in cancer patients

by Johannes Angerer,Medical University of ViennaBaseline cardiovascular toxicity risk assessment checklist. BNP, B-type natriuretic peptide; cTn, cardiac troponin; CTR-CVT, cancer therapy-relate
Rogue immune cells linked to leukemia found to be a key driver of autoimmune diseases

Rogue immune cells linked to leukemia found to be a key driver of autoimmune diseases

by Garvan Institute of Medical ResearchA killer T cell (centre) hunting a target cell. Credit: NIH Image GalleryGene variants associated with leukemia can produce "rogue" immune cells t

Rogue immune cells linked to leukemia found to be a key driver of autoimmune diseases

by Garvan Institute of Medical ResearchA killer T cell (centre) hunting a target cell. Credit: NIH Image GalleryGene variants associated with leukemia can produce "rogue" immune cells t
Study validates first-ever predictive AI biomarker of androgen deprivation therapy benefit in prostate cancer

Study validates first-ever predictive AI biomarker of androgen deprivation therapy benefit in prostate cancer

by University Hospitals Cleveland Medical CenterProstate cancer cells. Credit: NIH Image GalleryData from a new study published inNEJM Evidenceshows promise for personalized use of sh

Study validates first-ever predictive AI biomarker of androgen deprivation therapy benefit in prostate cancer

by University Hospitals Cleveland Medical CenterProstate cancer cells. Credit: NIH Image GalleryData from a new study published inNEJM Evidenceshows promise for personalized use of sh
How to lower your risk of breast cancer recurrence

How to lower your risk of breast cancer recurrence

by Leslie Orr,University of Rochester Medical CenterCredit: Unsplash/CC0 Public DomainMost women treated for breast cancer have something else in common: they worry about the cancer coming back.

How to lower your risk of breast cancer recurrence

by Leslie Orr,University of Rochester Medical CenterCredit: Unsplash/CC0 Public DomainMost women treated for breast cancer have something else in common: they worry about the cancer coming back.
Tumor-infiltrating lymphocyte therapy marks a milestone in cancer treatment, researchers say

Tumor-infiltrating lymphocyte therapy marks a milestone in cancer treatment, researchers say

byH. Lee Moffitt Cancer Center & Research InstituteCancer cell during cell division. Credit: National Institutes of HealthThe recent U.S. Food and Drug Administration approval of lifileucel,

Tumor-infiltrating lymphocyte therapy marks a milestone in cancer treatment, researchers say

byH. Lee Moffitt Cancer Center & Research InstituteCancer cell during cell division. Credit: National Institutes of HealthThe recent U.S. Food and Drug Administration approval of lifileucel,
Are the benefits of new cancer drugs worth the cost?

Are the benefits of new cancer drugs worth the cost?

by Sbarro Health Research Organization (SHRO)The rate of growth in costs (red) vs. outcomes (green) of cancer care, is here expressed as the derivative D[fx0] of both functions (i.e.: the angular coef

Are the benefits of new cancer drugs worth the cost?

by Sbarro Health Research Organization (SHRO)The rate of growth in costs (red) vs. outcomes (green) of cancer care, is here expressed as the derivative D[fx0] of both functions (i.e.: the angular coef
Research shows PSMA PET/CT imaging changes management for close to 50% of prostate cancer patients

Research shows PSMA PET/CT imaging changes management for close to 50% of prostate cancer patients

by Society of Nuclear Medicine and Molecular ImagingGraphical Abstract: Patients with detectable PSA (0.2-2.0 ng/mL) post-prostatectomy considered for salvage radiotherapy undergoing18F-DCFPyL P

Research shows PSMA PET/CT imaging changes management for close to 50% of prostate cancer patients

by Society of Nuclear Medicine and Molecular ImagingGraphical Abstract: Patients with detectable PSA (0.2-2.0 ng/mL) post-prostatectomy considered for salvage radiotherapy undergoing18F-DCFPyL P
How post-feeding breasts bounce back from the brink of death to kick-start milk production

How post-feeding breasts bounce back from the brink of death to kick-start milk production

byUniversity of SheffieldDelayed alveolar regression in Rac1−/− glands in involution. (A-D) Carmine staining of whole-mounted mammary glands of WT (A, C) and Rac1−/− (B, D) mice at postlactation

How post-feeding breasts bounce back from the brink of death to kick-start milk production

byUniversity of SheffieldDelayed alveolar regression in Rac1−/− glands in involution. (A-D) Carmine staining of whole-mounted mammary glands of WT (A, C) and Rac1−/− (B, D) mice at postlactation
Largest-ever atlas of normal breast cells brings unprecedented insights into mammary biology

Largest-ever atlas of normal breast cells brings unprecedented insights into mammary biology

by University of Texas M. D. Anderson Cancer CenterCredit: Unsplash/CC0 Public DomainA new study led by researchers at The University of Texas MD Anderson Cancer, University of California, Irvine

Largest-ever atlas of normal breast cells brings unprecedented insights into mammary biology

by University of Texas M. D. Anderson Cancer CenterCredit: Unsplash/CC0 Public DomainA new study led by researchers at The University of Texas MD Anderson Cancer, University of California, Irvine