Novel cell 'switches' found to promote lung cancer growth, treatment resistance

by Melissa Rohman,Northwestern UniversitySCLC cell lines have divergent gene regulatory networks and phenotypes. (A) Hierarchical clustering was performed using 53 SCLC cell lines. Silhouette wi

Updated on: December 21,2023 15

Novel cell 'switches' found to promote lung cancer growth, treatment resistance

by Melissa Rohman,Northwestern UniversitySCLC cell lines have divergent gene regulatory networks and phenotypes. (A) Hierarchical clustering was performed using 53 SCLC cell lines. Silhouette wi

Updated on:December 21,2023 15

Understanding lung cancer

by Jason HowlandCredit: Pixabay/CC0 Public DomainNovember is Lung Cancer Awareness Month. Lung cancer is the leading cause of cancer deaths worldwide. Each year, more people die from lung cancer than

Updated on: December 17,2023 10

Understanding lung cancer

by Jason HowlandCredit: Pixabay/CC0 Public DomainNovember is Lung Cancer Awareness Month. Lung cancer is the leading cause of cancer deaths worldwide. Each year, more people die from lung cancer than

Updated on:December 17,2023 10

EMA Accepts Marketing Application for Odronextamab in R/R DLBCL or Follicular Lymphoma

August 17, 2023Chris RyanThe European Medicines Agency has accepted a marketing authorization application seeking the approval of odronextamab for the treatment of adult patients with relapsed/refract

Updated on: October 12,2023 6

EMA Accepts Marketing Application for Odronextamab in R/R DLBCL or Follicular Lymphoma

August 17, 2023Chris RyanThe European Medicines Agency has accepted a marketing authorization application seeking the approval of odronextamab for the treatment of adult patients with relapsed/refract

Updated on:October 12,2023 6

Splicing deregulation detected and targeted in type of childhood leukemia

byUniversity of California - San DiegoA micrograph depicts acute myeloid leukemia cells. Though treatments have dramatically advanced, AML in children can become resistant to therapy. New resear

Updated on: December 21,2023 10

Splicing deregulation detected and targeted in type of childhood leukemia

byUniversity of California - San DiegoA micrograph depicts acute myeloid leukemia cells. Though treatments have dramatically advanced, AML in children can become resistant to therapy. New resear

Updated on:December 21,2023 10

Predicting lymphoma patients' treatment outcomes

byCedars-Sinai Medical CenterDistinct spatially resolved TME features according to relapse status. (A) Proportion for the indicated immune cell population by IMC-based cluster assignment. (B) Th

Updated on: December 26,2023 9

Predicting lymphoma patients' treatment outcomes

byCedars-Sinai Medical CenterDistinct spatially resolved TME features according to relapse status. (A) Proportion for the indicated immune cell population by IMC-based cluster assignment. (B) Th

Updated on:December 26,2023 9

Dual-action drug produces positive results in patients with advanced neuroendocrine tumors

byDana-Farber Cancer InstituteCredit: Pixabay/CC0 Public DomainA drug that simultaneously strikes cancer cells' growth circuits and pipeline to the bloodstream produced encouraging results i

Updated on: October 23,2023 33

Dual-action drug produces positive results in patients with advanced neuroendocrine tumors

byDana-Farber Cancer InstituteCredit: Pixabay/CC0 Public DomainA drug that simultaneously strikes cancer cells' growth circuits and pipeline to the bloodstream produced encouraging results i

Updated on:October 23,2023 33

Advancing Against Melanoma With Microneedles Technology

byColleen Fleisson August 22, 2023A novel strategy that combines a painless, minimally invasivemicroneedleplatform with the ability to absorb biomarker-rich fluid from the skin

Updated on: December 19,2023 42

Advancing Against Melanoma With Microneedles Technology

byColleen Fleisson August 22, 2023A novel strategy that combines a painless, minimally invasivemicroneedleplatform with the ability to absorb biomarker-rich fluid from the skin

Updated on:December 19,2023 42

Why does a leukemic mutation not always lead to leukemia? A new clue from a mouse study

byKeck School of Medicine of USCCredit: Pixabay/CC0 Public DomainWhy do some people with a genetic mutation associated with leukemia remain healthy, while others with the same mutation develop t

Updated on: January 08,2024 8

Why does a leukemic mutation not always lead to leukemia? A new clue from a mouse study

byKeck School of Medicine of USCCredit: Pixabay/CC0 Public DomainWhy do some people with a genetic mutation associated with leukemia remain healthy, while others with the same mutation develop t

Updated on:January 08,2024 8

ICI-Treated Synchronous mRCC Is Associated With Negative Survival Outcomes

July 17, 2023Ashling WahnerPatients with synchronous metastatic renal cell carcinoma who received first-line immunotherapy had worse survival outcomes compared with those with metachronous metastatic

Updated on: October 15,2023 156

ICI-Treated Synchronous mRCC Is Associated With Negative Survival Outcomes

July 17, 2023Ashling WahnerPatients with synchronous metastatic renal cell carcinoma who received first-line immunotherapy had worse survival outcomes compared with those with metachronous metastatic

Updated on:October 15,2023 156

Frontline Immunotherapy, Delayed Nephrectomy May Allow for Improved Disease Control in mRCC

July 14, 2023Caroline SeymourNeoadjuvant immunotherapy–based combinations led to reductions in tumor size and pathologic necrosis at the time of cytoreductive nephrectomy in patients with metastatic r

Updated on: October 12,2023 261

Frontline Immunotherapy, Delayed Nephrectomy May Allow for Improved Disease Control in mRCC

July 14, 2023Caroline SeymourNeoadjuvant immunotherapy–based combinations led to reductions in tumor size and pathologic necrosis at the time of cytoreductive nephrectomy in patients with metastatic r

Updated on:October 12,2023 261

Technology that determines success of CAR T-cell immunotherapy could advance treatment of lymphoma

by Laurie Fickman,University of HoustonNavin Varadarajan, M.D. Anderson Professor of chemical and biomolecular engineering, studied the dynamic interactions between T cells and tumor cells to de

Updated on: December 26,2023 8

Technology that determines success of CAR T-cell immunotherapy could advance treatment of lymphoma

by Laurie Fickman,University of HoustonNavin Varadarajan, M.D. Anderson Professor of chemical and biomolecular engineering, studied the dynamic interactions between T cells and tumor cells to de

Updated on:December 26,2023 8

Scalp Cooling for Chemo Hair Loss Strikes Out With Patients

M. Alexander Otto, PA, MMSTOPLINE:Most women withbreast cancerwho received scalp cooling did not perceive benefits in preventing hair loss, overall quality of life, body image, and other o

Updated on: October 26,2023 37

Scalp Cooling for Chemo Hair Loss Strikes Out With Patients

M. Alexander Otto, PA, MMSTOPLINE:Most women withbreast cancerwho received scalp cooling did not perceive benefits in preventing hair loss, overall quality of life, body image, and other o

Updated on:October 26,2023 37