Evaluation of ruxolitinib, a JAK inhibitor, in multiple myeloma

by Impact Journals LLCRuxolitinib exerts its anti-myeloma effects through several mechanisms. Credit:Oncotarget(2024). DOI: 10.18632/oncotarget.28547A new research perspective titled &quot

Updated on: May 07,2024

Evaluation of ruxolitinib, a JAK inhibitor, in multiple myeloma

by Impact Journals LLCRuxolitinib exerts its anti-myeloma effects through several mechanisms. Credit:Oncotarget(2024). DOI: 10.18632/oncotarget.28547A new research perspective titled &quot

Updated on:May 07,2024

CEACAMS 1, 5, and 6 in disease and cancer: Interactions with pathogens

by Impact Journals LLCSignaling of dimeric CEACAM1 long tail isoform in epithelial cells and T cells. Credit:Genes & Cancer(2023). DOI: 10.18632/genesandcancer.230A new review was rece

Updated on: December 25,2023

CEACAMS 1, 5, and 6 in disease and cancer: Interactions with pathogens

by Impact Journals LLCSignaling of dimeric CEACAM1 long tail isoform in epithelial cells and T cells. Credit:Genes & Cancer(2023). DOI: 10.18632/genesandcancer.230A new review was rece

Updated on:December 25,2023

Fat fuels aggressive brain cancers

byCardiff UniversityGliobastoma (astrocytoma) WHO grade IV—MRI coronal view, post contrast. 15 year old boy. Credit: Christaras A/ Wikipedia.Fat is powering tumour growth in brain cancer, finds

Updated on: December 18,2023

Fat fuels aggressive brain cancers

byCardiff UniversityGliobastoma (astrocytoma) WHO grade IV—MRI coronal view, post contrast. 15 year old boy. Credit: Christaras A/ Wikipedia.Fat is powering tumour growth in brain cancer, finds

Updated on:December 18,2023

New pancreatic cancer research could boost survival rates

byCU Anschutz Medical CampusGraphical abstract. Credit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.04.001A unique treatment combining radiation and immunotherapy can eradicate pancr

Updated on: January 13,2024

New pancreatic cancer research could boost survival rates

byCU Anschutz Medical CampusGraphical abstract. Credit:Cancer Cell(2023). DOI: 10.1016/j.ccell.2023.04.001A unique treatment combining radiation and immunotherapy can eradicate pancr

Updated on:January 13,2024

Patient step counts predict lung cancer treatment outcomes, study finds

byAmerican Society for Radiation OncologyCredit: CC0 Public DomainNumerous studies have shown that monitoring physical activity promotes better health—from reducing body mass index to watching f

Updated on: December 20,2023

Patient step counts predict lung cancer treatment outcomes, study finds

byAmerican Society for Radiation OncologyCredit: CC0 Public DomainNumerous studies have shown that monitoring physical activity promotes better health—from reducing body mass index to watching f

Updated on:December 20,2023

Five key medical advances related to bone marrow transplantation

by Heather Carlson Kehren,Mayo ClinicCredit: Mayo ClinicIn the six decades since blood and marrow transplantation was used to treat patients with blood cancers, this once experimental treatment

Updated on: January 30,2024

Five key medical advances related to bone marrow transplantation

by Heather Carlson Kehren,Mayo ClinicCredit: Mayo ClinicIn the six decades since blood and marrow transplantation was used to treat patients with blood cancers, this once experimental treatment

Updated on:January 30,2024

Modular chimeric cytokine receptors improve CAR T-cell therapy for solid tumors

bySt. Jude Children's Research HospitalTwo leucine zipper motifs endow ZipRs with constitutive signal transduction.a, Schematic of IL-2 receptor-based Zip2Rs with phosphorylated (p) JA

Updated on: January 26,2024

Modular chimeric cytokine receptors improve CAR T-cell therapy for solid tumors

bySt. Jude Children's Research HospitalTwo leucine zipper motifs endow ZipRs with constitutive signal transduction.a, Schematic of IL-2 receptor-based Zip2Rs with phosphorylated (p) JA

Updated on:January 26,2024

Inhibition of prmt5 by repurposing market drugs: A fresh therapeutic pathway for cancer treatment

by TranSpreadDevelopment of AlphaLISA HTS screen to identify specific PRMT5 inhibitors. (A) Principle of AlphaLISA technique adapted to HTS. Biotinylated histone H4 (a well-known PRMT5 substrate) was

Updated on: January 04,2024

Inhibition of prmt5 by repurposing market drugs: A fresh therapeutic pathway for cancer treatment

by TranSpreadDevelopment of AlphaLISA HTS screen to identify specific PRMT5 inhibitors. (A) Principle of AlphaLISA technique adapted to HTS. Biotinylated histone H4 (a well-known PRMT5 substrate) was

Updated on:January 04,2024

Fewer cases of melanoma observed among people taking vitamin D supplements

byUniversity of Eastern FinlandCredit: Unsplash/CC0 Public DomainFewer cases of melanoma were observed among regular users of vitamin D supplements than among non-users, a new study finds. Peopl

Updated on: December 22,2023

Fewer cases of melanoma observed among people taking vitamin D supplements

byUniversity of Eastern FinlandCredit: Unsplash/CC0 Public DomainFewer cases of melanoma were observed among regular users of vitamin D supplements than among non-users, a new study finds. Peopl

Updated on:December 22,2023

New form of immunotherapy under investigation for cancer that resists conventional T cell therapies

by Delthia Ricks , Medical XpressAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainMedical investigators are theorizing that a combination of t

Updated on: January 25,2024

New form of immunotherapy under investigation for cancer that resists conventional T cell therapies

by Delthia Ricks , Medical XpressAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainMedical investigators are theorizing that a combination of t

Updated on:January 25,2024

As cancer treatment advances, patients and doctors push back against drugs' harsh side effects

by Carla K. JohnsonJill Feldman, 54, poses for a photo at her home in Deerfield, Ill., Friday, Jan. 19, 2024. Lung cancer patient and advocate Jill Feldman takes pills at home that shrink tumors by bl

Updated on: June 25,2024

As cancer treatment advances, patients and doctors push back against drugs' harsh side effects

by Carla K. JohnsonJill Feldman, 54, poses for a photo at her home in Deerfield, Ill., Friday, Jan. 19, 2024. Lung cancer patient and advocate Jill Feldman takes pills at home that shrink tumors by bl

Updated on:June 25,2024

Chemically 'poisoned' protein acts as a molecular switch to spur cancer formation

byThe Scripps Research InstituteResearchers discovered that when the protein DNMT3B becomes S-nitrosylated in the presence of nitric oxide (NO), cancer-related genes become activated, leading to

Updated on: December 25,2023

Chemically 'poisoned' protein acts as a molecular switch to spur cancer formation

byThe Scripps Research InstituteResearchers discovered that when the protein DNMT3B becomes S-nitrosylated in the presence of nitric oxide (NO), cancer-related genes become activated, leading to

Updated on:December 25,2023