Diabetes drug reduces drug resistance in lung cancer, improving chemotherapy effectiveness

byUniversity of MissouriCredit: Pixabay/CC0 Public DomainA medication used to treat diabetic neuropathy may make chemotherapy treatments more effective for patients with lung cancer, according t

Updated on: August 01,2024

Diabetes drug reduces drug resistance in lung cancer, improving chemotherapy effectiveness

byUniversity of MissouriCredit: Pixabay/CC0 Public DomainA medication used to treat diabetic neuropathy may make chemotherapy treatments more effective for patients with lung cancer, according t

Updated on:August 01,2024

Scientists discover how satellite RNA leads to cancer

by Salk InstituteCell with injected hSATa RNA (left) shows a high level of a marker for DNA damage, γH2AX (middle). Merge image (right) shows satellite RNA and γH2AX in cells; DNA is blue. Credit

Updated on: March 12,2024

Scientists discover how satellite RNA leads to cancer

by Salk InstituteCell with injected hSATa RNA (left) shows a high level of a marker for DNA damage, γH2AX (middle). Merge image (right) shows satellite RNA and γH2AX in cells; DNA is blue. Credit

Updated on:March 12,2024

Researchers design 'prodrug' that targets cancer cells' big appetite for glutamine, leaving healthy cells unharmed

by Johns Hopkins University School of MedicineSchematic showing DRP-104's bio-activation to DON in tumor and bio-inactivation to an inert metabolite in GI tissues. Credit: Jennifer E. Fairman

Updated on: February 18,2024

Researchers design 'prodrug' that targets cancer cells' big appetite for glutamine, leaving healthy cells unharmed

by Johns Hopkins University School of MedicineSchematic showing DRP-104's bio-activation to DON in tumor and bio-inactivation to an inert metabolite in GI tissues. Credit: Jennifer E. Fairman

Updated on:February 18,2024

Exploring ferroptosis and its implications in lung cancer

by Cactus CommunicationsEven with advances in diagnosis and treatments, the survival rate of patients with lung cancer, remains to be low. Ferroptosis is a type of iron-dependent programmed cell death

Updated on: March 30,2024

Exploring ferroptosis and its implications in lung cancer

by Cactus CommunicationsEven with advances in diagnosis and treatments, the survival rate of patients with lung cancer, remains to be low. Ferroptosis is a type of iron-dependent programmed cell death

Updated on:March 30,2024

Study shows how circulating tumor cells target distant organs

by University of Southern CaliforniaDevelopment of brain metastasis is a complex process in which metastatic cells (green) overcome the protective effect of immune cells (red). Credit: University

Updated on: May 31,2024

Study shows how circulating tumor cells target distant organs

by University of Southern CaliforniaDevelopment of brain metastasis is a complex process in which metastatic cells (green) overcome the protective effect of immune cells (red). Credit: University

Updated on:May 31,2024

Why a promising breast cancer drug doesn't work—and how to improve it

by Katherine Fenz,Rockefeller UniversityER-mediated transcriptional resistance to BD inhibition. Credit:Nature Structural & Molecular Biology(2024). DOI: 10.1038/s41594-024-01384

Updated on: September 28,2024

Why a promising breast cancer drug doesn't work—and how to improve it

by Katherine Fenz,Rockefeller UniversityER-mediated transcriptional resistance to BD inhibition. Credit:Nature Structural & Molecular Biology(2024). DOI: 10.1038/s41594-024-01384

Updated on:September 28,2024

Polyploidy study reveals why some cancers are resistant to therapeutic drugs

byOsaka UniversityOverview of the study. (A) We created unique cells with double the usual number of chromosomes to investigate the relationship between polyploidy and DNA damage. (B) After trea

Updated on: November 09,2024

Polyploidy study reveals why some cancers are resistant to therapeutic drugs

byOsaka UniversityOverview of the study. (A) We created unique cells with double the usual number of chromosomes to investigate the relationship between polyploidy and DNA damage. (B) After trea

Updated on:November 09,2024

How pancreatic cancer defies treatment by leveraging a protein

by University of California - San DiegoPancreatic cancer cells (nuclei in blue) are shown growing as a sphere encased in membranes (red). Credit: National Cancer InstitutePancreatic cancer is the

Updated on: January 30,2024

How pancreatic cancer defies treatment by leveraging a protein

by University of California - San DiegoPancreatic cancer cells (nuclei in blue) are shown growing as a sphere encased in membranes (red). Credit: National Cancer InstitutePancreatic cancer is the

Updated on:January 30,2024

Protein linked to aggressive skin cancer

by Lund UniversityMelanoma in skin biopsy with H&E stain—this case may represent superficial spreading melanoma. Credit: Wikipedia/CC BY-SA 3.0Almost 300,000 people worldwide develop malignan

Updated on: May 07,2024

Protein linked to aggressive skin cancer

by Lund UniversityMelanoma in skin biopsy with H&E stain—this case may represent superficial spreading melanoma. Credit: Wikipedia/CC BY-SA 3.0Almost 300,000 people worldwide develop malignan

Updated on:May 07,2024

Artificial intelligence tool developed to predict risk of lung cancer

byMassachusetts General HospitalCredit: CC0 Public DomainLung cancer is the leading cause of cancer death in the United States and around the world. Low-dose chest computed tomography (LDCT) is

Updated on: January 02,2024

Artificial intelligence tool developed to predict risk of lung cancer

byMassachusetts General HospitalCredit: CC0 Public DomainLung cancer is the leading cause of cancer death in the United States and around the world. Low-dose chest computed tomography (LDCT) is

Updated on:January 02,2024

New drug could be advance against glioma brain tumors

by Dennis ThompsonAn experimental targeted therapy can dramatically slow the progress of common slow-growing brain cancers, a new clinical trial finds.The oral drug vorasidenib nearly tripled progress

Updated on: February 18,2024

New drug could be advance against glioma brain tumors

by Dennis ThompsonAn experimental targeted therapy can dramatically slow the progress of common slow-growing brain cancers, a new clinical trial finds.The oral drug vorasidenib nearly tripled progress

Updated on:February 18,2024

A naturally-occurring molecule shows promise as effective first-line treatment for prostate cancer

JANUARY 5, 2024byNottingham Trent UniversityLive-cell cytotoxicity analysis shows that carnosine induces the death of PC346Flu1 (A) and TRAMP-C1 (B) cells. Carnosine inhibited cell growth in a d

Updated on: March 28,2024

A naturally-occurring molecule shows promise as effective first-line treatment for prostate cancer

JANUARY 5, 2024byNottingham Trent UniversityLive-cell cytotoxicity analysis shows that carnosine induces the death of PC346Flu1 (A) and TRAMP-C1 (B) cells. Carnosine inhibited cell growth in a d

Updated on:March 28,2024