KIT Inhibitors Lead to Shift in Treatment of Systemic Mastocytosis

September 26, 2023Pankit Vachhani, MDPrithviraj Bose, MDThe hematologic neoplasm systemic mastocytosis is marked by the clonal proliferation of mast cells in the skin, bone marrow, gastrointestinal tr

Updated on: October 24,2023

KIT Inhibitors Lead to Shift in Treatment of Systemic Mastocytosis

September 26, 2023Pankit Vachhani, MDPrithviraj Bose, MDThe hematologic neoplasm systemic mastocytosis is marked by the clonal proliferation of mast cells in the skin, bone marrow, gastrointestinal tr

Updated on:October 24,2023

Intracellular recycling: The key to surviving potent anti-cancer drugs

byTokyo Medical and Dental UniversityER-phagy alleviates anthracycline cardiotoxicity. Credit: Department of Cardiovascular Medicine, TMDUA cell contains many specialized subunits, called organe

Updated on: January 10,2024

Intracellular recycling: The key to surviving potent anti-cancer drugs

byTokyo Medical and Dental UniversityER-phagy alleviates anthracycline cardiotoxicity. Credit: Department of Cardiovascular Medicine, TMDUA cell contains many specialized subunits, called organe

Updated on:January 10,2024

Timing androgen-deprivation therapy with radiation therapy improves outcomes in localized prostate cancer

byUniversity of California, Los AngelesUnadjusted Kaplan-Meier and cumulative incidence curves evaluating the associations between concurrent/adjuvant versus neoadjuvant/concurrent ADT sequencin

Updated on: December 20,2023

Timing androgen-deprivation therapy with radiation therapy improves outcomes in localized prostate cancer

byUniversity of California, Los AngelesUnadjusted Kaplan-Meier and cumulative incidence curves evaluating the associations between concurrent/adjuvant versus neoadjuvant/concurrent ADT sequencin

Updated on:December 20,2023

Study unveils the role of gamma-delta T cells in cancer immunology

byH. Lee Moffitt Cancer Center & Research InstituteComprehensive pan-cancer analysis of γδ TCRs. Credit:Cell Reports Medicine(2024). DOI: 10.1016/j.xcrm.2024.101764A new study pu

Updated on: October 26,2024

Study unveils the role of gamma-delta T cells in cancer immunology

byH. Lee Moffitt Cancer Center & Research InstituteComprehensive pan-cancer analysis of γδ TCRs. Credit:Cell Reports Medicine(2024). DOI: 10.1016/j.xcrm.2024.101764A new study pu

Updated on:October 26,2024

Overlooked strategy shows promise for treating KRAS-mutated colon cancer

Updated on: June 14,2025

Overlooked strategy shows promise for treating KRAS-mutated colon cancer

Updated on:June 14,2025

High BMI may improve cancer survival

byFlinders UniversityDr. Ganessan Kichenadasse from the Flinders Centre for Innovation in Cancer, South Australia. Credit: Flinders UniversityAbove average or high BMI—often linked to cancers, d

Updated on: December 20,2023

High BMI may improve cancer survival

byFlinders UniversityDr. Ganessan Kichenadasse from the Flinders Centre for Innovation in Cancer, South Australia. Credit: Flinders UniversityAbove average or high BMI—often linked to cancers, d

Updated on:December 20,2023

Pinpointing the prevalence of mismatch repair (MMR)-deficient rectal adenocarcinomas

byBrigham and Women's HospitalCredit: Pixabay/CC0 Public DomainA widely-circulated clinical trial published earlier this year in theNew England Journal of Medicine (NEJM)describe

Updated on: December 26,2023

Pinpointing the prevalence of mismatch repair (MMR)-deficient rectal adenocarcinomas

byBrigham and Women's HospitalCredit: Pixabay/CC0 Public DomainA widely-circulated clinical trial published earlier this year in theNew England Journal of Medicine (NEJM)describe

Updated on:December 26,2023

Researchers elucidate roles of TP63 and SOX2 in squamous cell cancer progression

byNational University of SingaporeCredit: CC0 Public DomainSquamous cell carcinomas (SCCs) are aggressive malignancies arising from the squamous epithelium of various organs, such as the esophag

Updated on: December 18,2023

Researchers elucidate roles of TP63 and SOX2 in squamous cell cancer progression

byNational University of SingaporeCredit: CC0 Public DomainSquamous cell carcinomas (SCCs) are aggressive malignancies arising from the squamous epithelium of various organs, such as the esophag

Updated on:December 18,2023

As medical debt rises, so do cancer death rates

by Dennis ThompsonFolks who are loaded down with medical debt are less likely to survive a bout of cancer, a new study reports.Researchers found that U.S. counties where more residents have medical de

Updated on: January 04,2024

As medical debt rises, so do cancer death rates

by Dennis ThompsonFolks who are loaded down with medical debt are less likely to survive a bout of cancer, a new study reports.Researchers found that U.S. counties where more residents have medical de

Updated on:January 04,2024

Differences in animal biology can affect cancer drug development

byWeill Cornell Medical CollegeDifferential co-occurrence and effects of KRAS, TP53 and LKB1 mutations on human and mouse LUADs (A) MSK Impact oncoprint of co-occurrence of KRAS, TP53 and LKB1 m

Updated on: December 20,2023

Differences in animal biology can affect cancer drug development

byWeill Cornell Medical CollegeDifferential co-occurrence and effects of KRAS, TP53 and LKB1 mutations on human and mouse LUADs (A) MSK Impact oncoprint of co-occurrence of KRAS, TP53 and LKB1 m

Updated on:December 20,2023

Coffee might give some men an edge battling prostate cancer

by Cara MurezFor some men battlingprostate cancer,drinking coffee may offer not just a quick pick-me-up but longer survival.Research is still in the early phases, but a new study finds an

Updated on: December 26,2023

Coffee might give some men an edge battling prostate cancer

by Cara MurezFor some men battlingprostate cancer,drinking coffee may offer not just a quick pick-me-up but longer survival.Research is still in the early phases, but a new study finds an

Updated on:December 26,2023

New clue discovered as to how and why cancer cells spread

by Gillian Rutherford,University of AlbertaViscosity enhances cell migration and promotes an ARP2/3-mediated dense actin network at the leading edge.a,b, Speeds of MDA-MB-231 cells (a) and

Updated on: December 22,2023

New clue discovered as to how and why cancer cells spread

by Gillian Rutherford,University of AlbertaViscosity enhances cell migration and promotes an ARP2/3-mediated dense actin network at the leading edge.a,b, Speeds of MDA-MB-231 cells (a) and

Updated on:December 22,2023