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Oncology
Prevention and treatment of tumors, and caring for cancer patients.
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Treatment of aggressive breast cancer improved by immunotherapy-chemotherapy combination

Treatment of aggressive breast cancer improved by immunotherapy-chemotherapy combination

byUniversity of Pittsburgh Schools of the Health SciencesLeisha Emens, M.D., Ph.D., co-leader of the UPMC Hillman Cancer Immunology and Immunotherapy Program. Credit: UPMCPatients with an aggres

Treatment of aggressive breast cancer improved by immunotherapy-chemotherapy combination

byUniversity of Pittsburgh Schools of the Health SciencesLeisha Emens, M.D., Ph.D., co-leader of the UPMC Hillman Cancer Immunology and Immunotherapy Program. Credit: UPMCPatients with an aggres
GZ17-6.02 with bexarotene kills mycosis fungoides cells: Study

GZ17-6.02 with bexarotene kills mycosis fungoides cells: Study

by Impact Journals LLCCombined macroautophagy and CD95 death receptor signaling facilitate additional tumor cell killing by GZ17-6.02. Credit: 2024 Booth et al.A new research paper titled "GZ17-6

GZ17-6.02 with bexarotene kills mycosis fungoides cells: Study

by Impact Journals LLCCombined macroautophagy and CD95 death receptor signaling facilitate additional tumor cell killing by GZ17-6.02. Credit: 2024 Booth et al.A new research paper titled "GZ17-6
Novel combination therapy has similar response rates to chemotherapy for high-risk luminal B breast cancer

Novel combination therapy has similar response rates to chemotherapy for high-risk luminal B breast cancer

byAmerican Association for Cancer ResearchNeoadjuvant treatment with the CDK4/6 inhibitor ribociclib (Kisqali) and the aromatase inhibitor letrozole (Femara) produced response rates similar to m

Novel combination therapy has similar response rates to chemotherapy for high-risk luminal B breast cancer

byAmerican Association for Cancer ResearchNeoadjuvant treatment with the CDK4/6 inhibitor ribociclib (Kisqali) and the aromatase inhibitor letrozole (Femara) produced response rates similar to m
Entrectinib effective, well-tolerated against ROS1 and NTRK lung cancers, especially with brain metastases

Entrectinib effective, well-tolerated against ROS1 and NTRK lung cancers, especially with brain metastases

by Garth Sundem,CU Anschutz Medical CampusRobert C. Doebele, MD, PhD. Credit: CU Anschutz Medical CampusPooled analysis of three phase 1 and 2 clinical trials published online ahead of print in

Entrectinib effective, well-tolerated against ROS1 and NTRK lung cancers, especially with brain metastases

by Garth Sundem,CU Anschutz Medical CampusRobert C. Doebele, MD, PhD. Credit: CU Anschutz Medical CampusPooled analysis of three phase 1 and 2 clinical trials published online ahead of print in
Researchers test previously approved FDA drugs to treat Lowe syndrome

Researchers test previously approved FDA drugs to treat Lowe syndrome

by Purdue UniversityR. Claudio Aguilar, a Purdue University researcher, has developed a patented therapeutic strategy for Lowe syndrome by repurposing two drugs previously approved by the U.S. Fo

Researchers test previously approved FDA drugs to treat Lowe syndrome

by Purdue UniversityR. Claudio Aguilar, a Purdue University researcher, has developed a patented therapeutic strategy for Lowe syndrome by repurposing two drugs previously approved by the U.S. Fo
Unraveling predisposition in bilateral Wilms tumor

Unraveling predisposition in bilateral Wilms tumor

bySt. Jude Children's Research HospitalSummary of Proposed Mechanisms for Bilateral Wilms tumor development. Credit:Nature Communications(2023). DOI: 10.1038/s41467-023-43730-0Ch

Unraveling predisposition in bilateral Wilms tumor

bySt. Jude Children's Research HospitalSummary of Proposed Mechanisms for Bilateral Wilms tumor development. Credit:Nature Communications(2023). DOI: 10.1038/s41467-023-43730-0Ch
Physical exercise prevents nerve damage during chemotherapy, sports scientist shows

Physical exercise prevents nerve damage during chemotherapy, sports scientist shows

byUniversity of BaselSports therapy to combat side effects: Fiona Streckmann with a patient during a neurological examination. A tuning fork is used to test vibration sensation, which can be alt

Physical exercise prevents nerve damage during chemotherapy, sports scientist shows

byUniversity of BaselSports therapy to combat side effects: Fiona Streckmann with a patient during a neurological examination. A tuning fork is used to test vibration sensation, which can be alt
Time of death or personal autonomy? Cancer patients prefer knowing functional prognosis over life expectancy

Time of death or personal autonomy? Cancer patients prefer knowing functional prognosis over life expectancy

byUniversity of TsukubaCredit: AI-generated imageProviding prognostic information is a vital component of cancer patient care. However, the specific information cancer patients prefer to receive

Time of death or personal autonomy? Cancer patients prefer knowing functional prognosis over life expectancy

byUniversity of TsukubaCredit: AI-generated imageProviding prognostic information is a vital component of cancer patient care. However, the specific information cancer patients prefer to receive
A promising treatment for ovarian cancer

A promising treatment for ovarian cancer

by Erin Matthews,Canadian Light SourceOvary. Credit: Public DomainOver 20,000 women across the U.S. and Canada are diagnosed with ovarian cancer annually. The symptoms of this disease are often

A promising treatment for ovarian cancer

by Erin Matthews,Canadian Light SourceOvary. Credit: Public DomainOver 20,000 women across the U.S. and Canada are diagnosed with ovarian cancer annually. The symptoms of this disease are often
Scientists reveal how different cancer cells 'team up' to help incurable childhood brain tumor spread

Scientists reveal how different cancer cells 'team up' to help incurable childhood brain tumor spread

byInstitute of Cancer ResearchSimulating cellular invasion (A) Illustration of simulation flow. (B) Summary statistics used to measure invasion: (i)traveling-wave solution to reaction-diff

Scientists reveal how different cancer cells 'team up' to help incurable childhood brain tumor spread

byInstitute of Cancer ResearchSimulating cellular invasion (A) Illustration of simulation flow. (B) Summary statistics used to measure invasion: (i)traveling-wave solution to reaction-diff
Conversation tool to help cancer patients with treatment choices

Conversation tool to help cancer patients with treatment choices

byLeiden UniversityCredit: Pixabay/CC0 Public DomainResearchers at the Leiden Institute of Advanced Computer Science (LIACS) are collaborating on the development of a conversation tool for patie

Conversation tool to help cancer patients with treatment choices

byLeiden UniversityCredit: Pixabay/CC0 Public DomainResearchers at the Leiden Institute of Advanced Computer Science (LIACS) are collaborating on the development of a conversation tool for patie
COVID-19 antiviral treatment should be taken for longer, says study

COVID-19 antiviral treatment should be taken for longer, says study

by University College LondonViral and spike antibody dynamics in molnupiravir (purple) and Usual Care (gray) arms. a) Median viral load ±95%CI with time, below limit of quantification (BLOQ) meas

COVID-19 antiviral treatment should be taken for longer, says study

by University College LondonViral and spike antibody dynamics in molnupiravir (purple) and Usual Care (gray) arms. a) Median viral load ±95%CI with time, below limit of quantification (BLOQ) meas