Regorafenib synergizes with TAS102 against multiple gastrointestinal cancers: Study

by Impact Journals LLCTAS102 in combination with regorafenib inhibits ERK1/2 and STAT3 signaling. Credit: 2024 Zhang et al.A new research paper waspublishedinOncotargettitled,

Updated on: July 10,2024

Regorafenib synergizes with TAS102 against multiple gastrointestinal cancers: Study

by Impact Journals LLCTAS102 in combination with regorafenib inhibits ERK1/2 and STAT3 signaling. Credit: 2024 Zhang et al.A new research paper waspublishedinOncotargettitled,

Updated on:July 10,2024

Researchers identify protein with DYRK1A-inhibiting effect that may have implications for Down syndrome

by Kyoto UniversityDYRK1A bound to FAM53C in the cytoplasm is less active. DYRK1A not bound to FAM53C in the nucleus is highly active. Functional abnormalities cause various neuropsychiatric deve

Updated on: February 20,2024

Researchers identify protein with DYRK1A-inhibiting effect that may have implications for Down syndrome

by Kyoto UniversityDYRK1A bound to FAM53C in the cytoplasm is less active. DYRK1A not bound to FAM53C in the nucleus is highly active. Functional abnormalities cause various neuropsychiatric deve

Updated on:February 20,2024

Researchers study the risk of false positives in colon cancer screening

by IDIBELL-Bellvitge Biomedical Research InstituteCancer—Histopathologic image of colonic carcinoid. Credit: Wikipedia/CC BY-SA 3.0Colorectal cancer can develop for months without producing any s

Updated on: June 04,2024

Researchers study the risk of false positives in colon cancer screening

by IDIBELL-Bellvitge Biomedical Research InstituteCancer—Histopathologic image of colonic carcinoid. Credit: Wikipedia/CC BY-SA 3.0Colorectal cancer can develop for months without producing any s

Updated on:June 04,2024

New treatment for a rare and aggressive cancer improves survival rates in breakthrough clinical trial

FEBRUARY 15, 2024byQueen Mary, University of LondonCredit: Pixabay/CC0 Public DomainAn innovative treatment significantly increases the survival of people with malignant mesothelioma, a rare but

Updated on: March 29,2024

New treatment for a rare and aggressive cancer improves survival rates in breakthrough clinical trial

FEBRUARY 15, 2024byQueen Mary, University of LondonCredit: Pixabay/CC0 Public DomainAn innovative treatment significantly increases the survival of people with malignant mesothelioma, a rare but

Updated on:March 29,2024

Researchers identify mechanism that allow ketamine to act both fast and slow

by Northwestern UniversityMultiple doses of ketamine do not increase the activity of immature neurons. Credit:Cellular and Molecular Life Sciences(2024). DOI: 10.1007/s00018-024-05121

Updated on: May 16,2024

Researchers identify mechanism that allow ketamine to act both fast and slow

by Northwestern UniversityMultiple doses of ketamine do not increase the activity of immature neurons. Credit:Cellular and Molecular Life Sciences(2024). DOI: 10.1007/s00018-024-05121

Updated on:May 16,2024

Treating Alzheimer's, Parkinson's, type 2 diabetes by eliminating protein aggregation in brain, pancreas

by Steve Martin,Purdue UniversityCredit: Wikimedia CommonsPurdue University researchers have taken the first steps to treat Alzheimer's disease, Parkinson's disease and Type 2 diabetes b

Updated on: May 06,2024

Treating Alzheimer's, Parkinson's, type 2 diabetes by eliminating protein aggregation in brain, pancreas

by Steve Martin,Purdue UniversityCredit: Wikimedia CommonsPurdue University researchers have taken the first steps to treat Alzheimer's disease, Parkinson's disease and Type 2 diabetes b

Updated on:May 06,2024

Study in mice examines impact of reused cooking oil on breast cancer progression

by Sharita Forrest ,University of Illinois at Urbana-ChampaignThe compounds in frying oils that are repeatedly reheated to high temperatures may trigger cell proliferation and metastases i

Updated on: April 23,2024

Study in mice examines impact of reused cooking oil on breast cancer progression

by Sharita Forrest ,University of Illinois at Urbana-ChampaignThe compounds in frying oils that are repeatedly reheated to high temperatures may trigger cell proliferation and metastases i

Updated on:April 23,2024

Surprising connection between COVID-19 and cancer regression

byNorthwestern UniversityCredit:Journal of Clinical Investigation(2024). DOI: 10.1172/JCI179527A new study led by scientists from the Northwestern Medicine Canning Thoracic Institute

Updated on: December 01,2024

Surprising connection between COVID-19 and cancer regression

byNorthwestern UniversityCredit:Journal of Clinical Investigation(2024). DOI: 10.1172/JCI179527A new study led by scientists from the Northwestern Medicine Canning Thoracic Institute

Updated on:December 01,2024

Localized genetic mutations may serve as biomarker for wide range of cancers

by Melissa Rohman,Northwestern UniversityCredit: Brianna Monroe/Northwestern UniversityA team of Northwestern Medicine investigators have successfully localized novel molecular mechanisms behind

Updated on: December 26,2023

Localized genetic mutations may serve as biomarker for wide range of cancers

by Melissa Rohman,Northwestern UniversityCredit: Brianna Monroe/Northwestern UniversityA team of Northwestern Medicine investigators have successfully localized novel molecular mechanisms behind

Updated on:December 26,2023

Understanding breast cancer recurrence, metastatic spread

byUniversity of CincinnatiCredit: Unsplash/CC0 Public DomainDespite advancements in cancer detection and treatment, breast cancer that comes back or spreads still presents a challenge to researc

Updated on: December 28,2023

Understanding breast cancer recurrence, metastatic spread

byUniversity of CincinnatiCredit: Unsplash/CC0 Public DomainDespite advancements in cancer detection and treatment, breast cancer that comes back or spreads still presents a challenge to researc

Updated on:December 28,2023

Unique insights into differences between primary and metastatic cancer by large-scale DNA data analyses

by Hartwig Medical FoundationInference of HLA-I tumor status with LILAC. a, Representation of the six immune escape pathways considered in the present study alongside their associated genes (adapted f

Updated on: January 07,2024

Unique insights into differences between primary and metastatic cancer by large-scale DNA data analyses

by Hartwig Medical FoundationInference of HLA-I tumor status with LILAC. a, Representation of the six immune escape pathways considered in the present study alongside their associated genes (adapted f

Updated on:January 07,2024

Delivering oxygen to tumors may be key in overcoming radiation therapy resistance

by National Institute of Biomedical Imaging and BioengineeringOxygen in tumors is necessary for radiotherapy to effectively treat cancer, but when tumors are hypoxic, this method can fail. A new strat

Updated on: January 10,2024

Delivering oxygen to tumors may be key in overcoming radiation therapy resistance

by National Institute of Biomedical Imaging and BioengineeringOxygen in tumors is necessary for radiotherapy to effectively treat cancer, but when tumors are hypoxic, this method can fail. A new strat

Updated on:January 10,2024