Tackling resistance to HIF2 drugs with an RNA-based therapy

byUT Southwestern Medical CenterDownregulation of HIF2α by ARO-HIF2 in patient tumor biopsies. Credit: Dr. Payal KapurExpected to be diagnosed in 2% of men and 1% of women in the U.S., kidney ca

Updated on: December 28,2023

Tackling resistance to HIF2 drugs with an RNA-based therapy

byUT Southwestern Medical CenterDownregulation of HIF2α by ARO-HIF2 in patient tumor biopsies. Credit: Dr. Payal KapurExpected to be diagnosed in 2% of men and 1% of women in the U.S., kidney ca

Updated on:December 28,2023

CAR T cell immunotherapy for solid tumors? First, you have to break the cancers' sugar shield

by Delthia Ricks , Medical XpressModeling of the impact of tumor N-glycans on the targeting by CAR T cells. Left, the N-glycan decoration of tumors 1) repels CAR T cells by impeding immunological syna

Updated on: April 09,2024

CAR T cell immunotherapy for solid tumors? First, you have to break the cancers' sugar shield

by Delthia Ricks , Medical XpressModeling of the impact of tumor N-glycans on the targeting by CAR T cells. Left, the N-glycan decoration of tumors 1) repels CAR T cells by impeding immunological syna

Updated on:April 09,2024

Study shows elevated cancer risk for women with endometriosis

byHuntsman Cancer InstituteCredit: CC0 Public DomainA landmark study from researchers at Huntsman Cancer Institute at the University of Utah (the U), the Spencer Fox Eccles School of Medicine at

Updated on: August 03,2024

Study shows elevated cancer risk for women with endometriosis

byHuntsman Cancer InstituteCredit: CC0 Public DomainA landmark study from researchers at Huntsman Cancer Institute at the University of Utah (the U), the Spencer Fox Eccles School of Medicine at

Updated on:August 03,2024

Chemo drug may cause significant hearing loss in longtime cancer survivors

byUniversity of South FloridaCredit: Unsplash/CC0 Public DomainAn interdisciplinary study led by researchers at the University of South Florida and Indiana University has uncovered significant f

Updated on: July 08,2024

Chemo drug may cause significant hearing loss in longtime cancer survivors

byUniversity of South FloridaCredit: Unsplash/CC0 Public DomainAn interdisciplinary study led by researchers at the University of South Florida and Indiana University has uncovered significant f

Updated on:July 08,2024

Novel late-stage colorectal cancer treatment proves effective in preclinical models

by Angel Mendez,University of Minnesota Medical SchoolThe low T cells are due to exosomal, immunosuppressive miRNAs that disrupt T cell function and loss of T cells in the tumor environment. Cre

Updated on: April 29,2024

Novel late-stage colorectal cancer treatment proves effective in preclinical models

by Angel Mendez,University of Minnesota Medical SchoolThe low T cells are due to exosomal, immunosuppressive miRNAs that disrupt T cell function and loss of T cells in the tumor environment. Cre

Updated on:April 29,2024

Is the pap smear on the way out?

by Steven Reinberg, Healthday Reporter(HealthDay)—The Pap test, used for over 50 years to spot the early signs of cervical cancer, may soon become a thing of the past, new research suggests.Its replac

Updated on: April 01,2024

Is the pap smear on the way out?

by Steven Reinberg, Healthday Reporter(HealthDay)—The Pap test, used for over 50 years to spot the early signs of cervical cancer, may soon become a thing of the past, new research suggests.Its replac

Updated on:April 01,2024

'Magic bullet' takes aim at pancreatic cancer

by University of South AustraliaAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainEvery day, more than 1200 people worldwide are told they

Updated on: March 14,2024

'Magic bullet' takes aim at pancreatic cancer

by University of South AustraliaAxial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domainEvery day, more than 1200 people worldwide are told they

Updated on:March 14,2024

Modeling the use of beta radiation in cancer treatment

bySpringerIllustration of beta decay proceeding against the backdrop of a Monte Carlo simulation. Credit: Robert LeaTreating superficial skin tumors especially when they are located above cartil

Updated on: January 02,2024

Modeling the use of beta radiation in cancer treatment

bySpringerIllustration of beta decay proceeding against the backdrop of a Monte Carlo simulation. Credit: Robert LeaTreating superficial skin tumors especially when they are located above cartil

Updated on:January 02,2024

Subtypes of fibroblasts associated with skin cancer could lead to novel immunotherapies

byMedical University of ViennaSchematic summary of spatial distribution of distinct CAF subsets in human skin cancer. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-5390

Updated on: December 01,2024

Subtypes of fibroblasts associated with skin cancer could lead to novel immunotherapies

byMedical University of ViennaSchematic summary of spatial distribution of distinct CAF subsets in human skin cancer. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-5390

Updated on:December 01,2024

Pulsed electromagnetic field application technique for preventing bone loss due to radiotherapy

by Bob Yirka , Medical XpressPEMF ameliorates focal radiation–induced bone loss by modulating osteoblasts. (A) Schematic representation of focal radiation and PEMF administration. (B) Representative m

Updated on: December 28,2023

Pulsed electromagnetic field application technique for preventing bone loss due to radiotherapy

by Bob Yirka , Medical XpressPEMF ameliorates focal radiation–induced bone loss by modulating osteoblasts. (A) Schematic representation of focal radiation and PEMF administration. (B) Representative m

Updated on:December 28,2023

Study reveals mechanism linking heart disease to cancer development

byTel-Aviv UniversityCredit: CC0 Public DomainResearchers at Tel Aviv University (TAU) and the Leviev Cardiothoracic and Vascular Center at the Sheba Medical Center have found a mechanism respon

Updated on: April 28,2024

Study reveals mechanism linking heart disease to cancer development

byTel-Aviv UniversityCredit: CC0 Public DomainResearchers at Tel Aviv University (TAU) and the Leviev Cardiothoracic and Vascular Center at the Sheba Medical Center have found a mechanism respon

Updated on:April 28,2024

High-resolution brain tumor mapping reveals possible reason why some patients don't respond to new drug

byWeizmann Institute of ScienceGraphical abstract. Credit:Cell(2024). DOI: 10.1016/j.cell.2024.03.029The cells that make up cancerous brain tumors are extremely varied and sometimes

Updated on: September 10,2024

High-resolution brain tumor mapping reveals possible reason why some patients don't respond to new drug

byWeizmann Institute of ScienceGraphical abstract. Credit:Cell(2024). DOI: 10.1016/j.cell.2024.03.029The cells that make up cancerous brain tumors are extremely varied and sometimes

Updated on:September 10,2024