Novel biomarker for immune checkpoint inhibitors identified in human lethal cancers

by Liu Jia,Chinese Academy of SciencesA model depicting how the SETD2 inactivation sensitizes cancer cells to immune checkpoint blockade through the NR2F1-STAT1 pathway. Credit: Prof. Wang Yuexi

Updated on: January 26,2024

Novel biomarker for immune checkpoint inhibitors identified in human lethal cancers

by Liu Jia,Chinese Academy of SciencesA model depicting how the SETD2 inactivation sensitizes cancer cells to immune checkpoint blockade through the NR2F1-STAT1 pathway. Credit: Prof. Wang Yuexi

Updated on:January 26,2024

Researchers develop scalable synthesis of cancer-fighting compounds

byH. Lee Moffitt Cancer Center & Research InstituteCredit:Science Advances(2024). DOI: 10.1126/sciadv.adp9375Withanolides, a class of naturally occurring compounds found in plant

Updated on: July 08,2024

Researchers develop scalable synthesis of cancer-fighting compounds

byH. Lee Moffitt Cancer Center & Research InstituteCredit:Science Advances(2024). DOI: 10.1126/sciadv.adp9375Withanolides, a class of naturally occurring compounds found in plant

Updated on:July 08,2024

New hope for prostate cancer: New form of immunotherapy could prevent resistance to hormone therapy

byUniversity of SheffieldADT stimulates the PV accumulation of FR-β+ TAMs in mouse (Myc-CaP) and localized, human prostate tumors. Credit:Journal for ImmunoTherapy of Cancer(2024). D

Updated on: August 28,2024

New hope for prostate cancer: New form of immunotherapy could prevent resistance to hormone therapy

byUniversity of SheffieldADT stimulates the PV accumulation of FR-β+ TAMs in mouse (Myc-CaP) and localized, human prostate tumors. Credit:Journal for ImmunoTherapy of Cancer(2024). D

Updated on:August 28,2024

'3D mammography' almost halves the incidence of breast cancer between two screening tests in clinical trial

byUniversity of CórdobaDBT interval carcinoma. A 60-year-old asymptomatic patient who underwent a repeat mammographic study 20months after the screening study interpreted as normal due to

Updated on: March 30,2024

'3D mammography' almost halves the incidence of breast cancer between two screening tests in clinical trial

byUniversity of CórdobaDBT interval carcinoma. A 60-year-old asymptomatic patient who underwent a repeat mammographic study 20months after the screening study interpreted as normal due to

Updated on:March 30,2024

How much sun can (and should) I get?

by Katie Lee and Rachel Neale,The ConversationCredit: Unsplash/CC0 Public DomainAs we slide of out summer, you might be wondering how careful you need to be about sun exposure. Excessive exposur

Updated on: March 30,2024

How much sun can (and should) I get?

by Katie Lee and Rachel Neale,The ConversationCredit: Unsplash/CC0 Public DomainAs we slide of out summer, you might be wondering how careful you need to be about sun exposure. Excessive exposur

Updated on:March 30,2024

PSA levels after treatment may not be reliable predictor of survival for patients with prostate cancer

by University of California, Los AngelesCredit: Unsplash/CC0 Public DomainA UCLA-led study has found treatments that reduce the risk of being diagnosed with a cancer recurrence based on rising pr

Updated on: February 18,2024

PSA levels after treatment may not be reliable predictor of survival for patients with prostate cancer

by University of California, Los AngelesCredit: Unsplash/CC0 Public DomainA UCLA-led study has found treatments that reduce the risk of being diagnosed with a cancer recurrence based on rising pr

Updated on:February 18,2024

Researchers investigate cancer cluster in Alabama town

by Lindsey Piercy,University of KentuckyCredit: Unsplash/CC0 Public DomainFruithurst is your quintessential small town. Located in Cleburne County, Alabama—just five miles on the other side of t

Updated on: February 20,2024

Researchers investigate cancer cluster in Alabama town

by Lindsey Piercy,University of KentuckyCredit: Unsplash/CC0 Public DomainFruithurst is your quintessential small town. Located in Cleburne County, Alabama—just five miles on the other side of t

Updated on:February 20,2024

Trial results show PARP inhibitor benefit in 'BRCA-like' breast cancer

by SWOG Cancer Research NetworkCredit: Unsplash/CC0 Public DomainResults from the SWOG S1416 clinical trial show that adding veliparib to chemotherapy can significantly extend progression-free surviva

Updated on: January 04,2024

Trial results show PARP inhibitor benefit in 'BRCA-like' breast cancer

by SWOG Cancer Research NetworkCredit: Unsplash/CC0 Public DomainResults from the SWOG S1416 clinical trial show that adding veliparib to chemotherapy can significantly extend progression-free surviva

Updated on:January 04,2024

Computational method used to directly measure tumors shows hypertranscription is ubiquitous across cancers

by Bob Yirka , Medical XpressOverview of RNA output analysis with RNAmp. (A) Hypertranscription occurs when cancer cells elevate their RNA output above normal cell levels (left). Upon RNA extraction f

Updated on: February 20,2024

Computational method used to directly measure tumors shows hypertranscription is ubiquitous across cancers

by Bob Yirka , Medical XpressOverview of RNA output analysis with RNAmp. (A) Hypertranscription occurs when cancer cells elevate their RNA output above normal cell levels (left). Upon RNA extraction f

Updated on:February 20,2024

Enlarged genotype-phenotype correlation for a three-base pair deletion in neurofibromatosis type 1

by Jeff Hansen,University of Alabama at BirminghamLudwine Messiaen, Ph.D., left, and Magdalena Koczkowska, Ph.D. Credit: University of Alabama at BirminghamInternational collaborative research l

Updated on: March 14,2024

Enlarged genotype-phenotype correlation for a three-base pair deletion in neurofibromatosis type 1

by Jeff Hansen,University of Alabama at BirminghamLudwine Messiaen, Ph.D., left, and Magdalena Koczkowska, Ph.D. Credit: University of Alabama at BirminghamInternational collaborative research l

Updated on:March 14,2024

Exploring how gene mutations in tumors impact radiation sensitivity

byNorthwestern UniversityHigh-content irradiation platform reproducibility for the duration of the profiling effort. The signal-to-noise ratio (SNR), in blue represents the in-plate ratio of rad

Updated on: January 07,2024

Exploring how gene mutations in tumors impact radiation sensitivity

byNorthwestern UniversityHigh-content irradiation platform reproducibility for the duration of the profiling effort. The signal-to-noise ratio (SNR), in blue represents the in-plate ratio of rad

Updated on:January 07,2024

As patients live longer, new criteria needed for prostate cancer trials

JANUARY 26, 2024by Olivia Dimmer,Northwestern UniversityKaplan-Meier curves for (A) OS and rPFS and (B) OS and cPFS. cPFS=clinical progression-free survival; OS=overall survival; rPFS=radiograph

Updated on: March 25,2024

As patients live longer, new criteria needed for prostate cancer trials

JANUARY 26, 2024by Olivia Dimmer,Northwestern UniversityKaplan-Meier curves for (A) OS and rPFS and (B) OS and cPFS. cPFS=clinical progression-free survival; OS=overall survival; rPFS=radiograph

Updated on:March 25,2024